Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? (Q34976913)

5 August 2017

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title

Gene regulation of connective tissue growth factor: new targets for antifibrotic therapy? (English)

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5 August 2017

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Ingrid E Blom

1

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PubMed ID

12392758

5 August 2017

Roel Goldschmeding

series ordinal

2

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PubMed ID

12392758

5 August 2017

Andrew Leask

series ordinal

3

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5 August 2017

1 October 2002

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5 August 2017

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5 August 2017

21

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5 August 2017

6

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5 August 2017

473-482

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Tumor necrosis factor alpha suppresses the induction of connective tissue growth factor by transforming growth factor-beta in normal and scleroderma fibroblasts

5 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Identification of human ccn2 (connective tissue growth factor) promoter polymorphisms

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

The modular architecture of a new family of growth regulators related to connective tissue growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Biology of TGF-beta in knockout and transgenic mouse models

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Thrombin is a potent inducer of connective tissue growth factor production via proteolytic activation of protease-activated receptor-1.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

The angiogenic factors Cyr61 and connective tissue growth factor induce adhesive signaling in primary human skin fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Connective tissue growth factor is secreted through the Golgi and is degraded in the endosome

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

CTGF expression in mesangial cells: involvement of SMADs, MAP kinase, and PKC.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Connective tissue growth factor: a novel regulator of mucosal repair and fibrosis in inflammatory bowel disease?

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Connective tissue growth factor mediates transforming growth factor beta-induced collagen synthesis: down-regulation by cAMP

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Increased MMP-2 expression in connective tissue growth factor over-expression vascular smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Peroxisome proliferator-activated receptor gamma inhibits transforming growth factor beta-induced connective tissue growth factor expression in human aortic smooth muscle cells by interfering with Smad3

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Regulation of connective tissue growth factor (ccn2; ctgf) gene expression in human mesangial cells: modulation by HMG CoA reductase inhibitors (statins).

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Differential expression, surface binding, and response to connective tissue growth factor in lung fibroblast subpopulations.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Calcium oxalate monohydrate crystals stimulate gene expression in renal epithelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Transforming growth factor-beta(1) induces apoptosis via connective tissue growth factor in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Overexpression of connective tissue growth factor gene induces apoptosis in human aortic smooth muscle cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Static pressure regulates connective tissue growth factor expression in human mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

CTGF and SMADs, maintenance of scleroderma phenotype is independent of SMAD signaling

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Direct thrombin inhibition reduces lung collagen, accumulation, and connective tissue growth factor mRNA levels in bleomycin-induced pulmonary fibrosis.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Nitric oxide down-regulates connective tissue growth factor in rat mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Fibroblasts in mechanically stressed collagen lattices assume a "synthetic" phenotype

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Cyr61 and Fisp12 are both ECM-associated signaling molecules: activities, metabolism, and localization during development

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Characterization of a mouse ctgf 3'-UTR segment that mediates repressive regulation of gene expression.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Novel mode of processing and secretion of connective tissue growth factor/ecogenin (CTGF/Hcs24) in chondrocytic HCS-2/8 cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Involvement of cis-acting repressive element(s) in the 3'-untranslated region of human connective tissue growth factor gene

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Identification of an RNA element that confers post-transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: similarities to retroviral RNA-protein interactions

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

The control of ccn2 (ctgf) gene expression in normal and scleroderma fibroblasts

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Molecular cloning of genes differentially regulated by TNF-alpha in bovine aortic endothelial cells, fibroblasts and smooth muscle cells.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

DNA microarray reveals changes in gene expression of shear stressed human umbilical vein endothelial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Suppression subtractive hybridization identifies high glucose levels as a stimulus for expression of connective tissue growth factor and other genes in human mesangial cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Demonstration of receptors specific for connective tissue growth factor on a human chondrocytic cell line (HCS-2/8).

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Human connective tissue growth factor is expressed in advanced atherosclerotic lesions

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Hydrogen peroxide is a novel inducer of connective tissue growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Differential gene expression in migrating renal epithelial cells after wounding

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Factor VIIa and thrombin induce the expression of Cyr61 and connective tissue growth factor, extracellular matrix signaling proteins that could act as possible downstream mediators in factor VIIa x tissue factor-induced signal transduction

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Des-Arg(10)-kallidin engagement of the B1 receptor stimulates type I collagen synthesis via stabilization of connective tissue growth factor mRNA.

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Mechanical stress is required for high-level expression of connective tissue growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Identification of connective tissue growth factor as a target of WT1 transcriptional regulation

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Characterization of cell-associated and soluble forms of connective tissue growth factor (CTGF) produced by fibroblast cells in vitro

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Iloprost suppresses connective tissue growth factor production in fibroblasts and in the skin of scleroderma patients

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Vascular endothelial growth factor induces expression of connective tissue growth factor via KDR, Flt1, and phosphatidylinositol 3-kinase-akt-dependent pathways in retinal vascular cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Lefty inhibits receptor-regulated Smad phosphorylation induced by the activated transforming growth factor-beta receptor

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Connective tissue growth factor in tubulointerstitial injury of diabetic nephropathy

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

Expression and differential regulation of connective tissue growth factor in pancreatic cancer cells

1 reference

https://api.crossref.org/works/10.1016%2FS0945-053X%2802%2900055-0

7 January 2021

10.1016/S0945-053X(02)00055-0

Identifiers

DOI

1 reference

5 August 2017

1 reference

PubMed ID

12392758