Can a single model explain both breast cancer and prostate cancer? (Q36054603)

11 August 2017

1 reference

3 December 2020

1 reference

PubMed publication ID

17678531

title

Can a single model explain both breast cancer and prostate cancer? (English)

1 reference

11 August 2017

1 reference

3 December 2020

1 reference

3 December 2020

1 reference

3 December 2020

A Edward Friedman

1

1 reference

11 August 2017

language of work or name

1 reference

1 August 2007

7 references

Theoretical Biology and Medical Modelling

11 August 2017

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

3 December 2020

7 references

11 August 2017

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

3 December 2020

4

1 reference

11 August 2017

28

1 reference

Creative Commons Attribution 2.0 Generic

11 August 2017

6 references

13 March 2019

3 April 2019

20 June 2019

17 June 2019

19 September 2019

on focus list of Wikimedia project

3 December 2020

copyright status

copyrighted

0 references

ScienceSource

0 references

cites work

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Membrane androgen receptor activation induces apoptotic regression of human prostate cancer cells in vitro and in vivo

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The human prostate cancer cell line LNCaP bears functional membrane testosterone receptors that increase PSA secretion and modify actin cytoskeleton

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2 October 2017

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Testosterone inhibits estrogen-induced mammary epithelial proliferation and suppresses estrogen receptor expression

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Androgen-induced proliferative quiescence in prostate cancer cells: the role of AS3 as its mediator

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p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis

2 October 2017

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Calreticulin expression is associated with androgen regulation of the sensitivity to calcium ionophore-induced apoptosis in LNCaP prostate cancer cells

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Progression of LNCaP prostate tumor cells during androgen deprivation: hormone-independent growth, repression of proliferation by androgen, and role for p27Kip1 in androgen-induced cell cycle arrest

2 October 2017

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2 October 2017

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2 October 2017

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Genistein-induced apoptosis of prostate cancer cells is preceded by a specific decrease in focal adhesion kinase activity

2 October 2017

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2 October 2017

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17 beta-estradiol stimulates a rapid Ca2+ influx in LNCaP human prostate cancer cells

2 October 2017

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Human prostate tumor growth in athymic mice: inhibition by androgens and stimulation by finasteride

2 October 2017

1 reference

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Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.

2 October 2017

1 reference

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Overexpression of bcl-2 protects prostate cancer cells from apoptosis in vitro and confers resistance to androgen depletion in vivo.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Aromatase in the normal breast and breast cancer

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Androgen-induced inhibition of proliferation in human breast cancer MCF7 cells transfected with androgen receptor.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Role of calcium in the programmed death of rat prostatic glandular cells

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Low serum testosterone and mortality in male veterans

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Serum testosterone and the risk of prostate cancer: potential implications for testosterone therapy

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Androgen receptor signaling and vitamin D receptor action in prostate cancer cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Genistein induces cell growth inhibition in prostate cancer through the suppression of telomerase activity

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Endogenous sex hormones and subsequent breast cancer in premenopausal women

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Low androgenization index in elderly women and elderly men with Alzheimer's disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Germ-line mutations in BRCA1 or BRCA2 in the normal breast are associated with altered expression of estrogen-responsive proteins and the predominance of progesterone receptor A.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Apoptosis induction by 1alpha,25-dihydroxyvitamin D3 in prostate cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Inhibition of 5alpha-reductase in rat prostate reveals differential regulation of androgen-response gene expression by testosterone and dihydrotestosterone

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Role of mitochondria and caspases in vitamin D-mediated apoptosis of MCF-7 breast cancer cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Sex hormone-induced prostatic carcinogenesis in the noble rat: the role of insulin-like growth factor-I (IGF-I) and vascular endothelial growth factor (VEGF) in the development of prostate cancer.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

The influence of progesterone on the conversion of 17-hydroxyprogesterone to testosterone in the mouse testis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

A randomized trial comparing radical prostatectomy with watchful waiting in early prostate cancer

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2014741

Induction of apoptosis by mifepristone and tamoxifen in human LNCaP prostate cancer cells in culture

5 December 2018

1 reference

12 December 2020

Malignant breast epithelial cells stimulate aromatase expression via promoter II in human adipose fibroblasts: an epithelial-stromal interaction in breast tumors mediated by CCAAT/enhancer binding protein beta

1 reference

12 December 2020

Characterization of the Cytosol Androgen Receptor of the Human Prostate*

1 reference

12 December 2020

Endogenous concentration and subcellular distribution of estrogens in normal and malignant human breast tissue

1 reference

12 December 2020

Aromatase mRNA levels in benign prostatic hyperplasia and prostate cancer

1 reference

12 December 2020

Evidence for an alternative mechanism for maintaining telomere length in human tumors and tumor-derived cell lines

1 reference

12 December 2020

Breast and prostate cancer: an analysis of common epidemiological, genetic, and biochemical features

1 reference

12 December 2020

Pretreatment total testosterone levels in patients with prostate cancer in the past two decades in Japan

1 reference

12 December 2020

Identifiers

DOI

10.1186/1742-4682-4-28

1 reference

Dimensions Publication ID

11 August 2017

0 references

1 reference

11 August 2017

PubMed publication ID

17678531

1 reference