A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation (Q36058628)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22675211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

title

A Notch-dependent molecular circuitry initiates pancreatic endocrine and ductal cell differentiation (English)

1 reference

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3 February 2020

1 reference

5

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3 February 2020

Anne Grapin-Botton

6

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3 February 2020

author name string

Hung Ping Shih

1

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3 February 2020

Janel L Kopp

2

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3 February 2020

Manbir Sandhu

3

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3 February 2020

Claire L Dubois

4

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3 February 2020

Maike Sander

7

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3 February 2020

language of work or name

English

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publication date

6 June 2012

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3 February 2020

number of pages

12

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inferred from page(s)

published in

Development

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3 February 2020

volume

139

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3 February 2020

issue

14

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3 February 2020

page(s)

2488-2499

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Ptf1a-mediated control of Dll1 reveals an alternative to the lateral inhibition mechanism

3 February 2020

cites work

1 reference

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Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development

2 October 2017

1 reference

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Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytes

2 October 2017

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Sox9-haploinsufficiency causes glucose intolerance in mice

2 October 2017

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A role for the primary cilium in Notch signaling and epidermal differentiation during skin development

2 October 2017

1 reference

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SOX9 induces and maintains neural stem cells

2 October 2017

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Nkx6 transcription factors and Ptf1a function as antagonistic lineage determinants in multipotent pancreatic progenitors.

2 October 2017

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Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

2 October 2017

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Conditional mutation of Pkd2 causes cystogenesis and upregulates beta-catenin

2 October 2017

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Impaired Wnt-beta-catenin signaling disrupts adult renal homeostasis and leads to cystic kidney ciliopathy

2 October 2017

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Notch signaling controls the balance of ciliated and secretory cell fates in developing airways

2 October 2017

1 reference

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Dynamic Notch signaling in neural progenitor cells and a revised view of lateral inhibition

2 October 2017

1 reference

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A dosage-dependent requirement for Sox9 in pancreatic endocrine cell formation

2 October 2017

1 reference

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Oscillations in notch signaling regulate maintenance of neural progenitors

2 October 2017

1 reference

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Myt1 and Ngn3 form a feed-forward expression loop to promote endocrine islet cell differentiation

2 October 2017

1 reference

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Sox9 coordinates a transcriptional network in pancreatic progenitor cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Preservation of proliferating pancreatic progenitor cells by Delta-Notch signaling in the embryonic chicken pancreas

2 October 2017

1 reference

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Physiological Notch signaling promotes gliogenesis in the developing peripheral and central nervous systems

2 October 2017

1 reference

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Cranial muscle defects of Pitx2 mutants result from specification defects in the first branchial arch

2 October 2017

1 reference

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Notch signaling, gamma-secretase inhibitors, and cancer therapy

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

SOX9 is required for maintenance of the pancreatic progenitor cell pool

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Osteopontin is a novel marker of pancreatic ductal tissues and of undifferentiated pancreatic precursors in mice

2 October 2017

1 reference

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The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas

2 October 2017

1 reference

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The Wnt signaling pathway in development and disease

2 October 2017

1 reference

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Skeletal defects in ringelschwanz mutant mice reveal that Lrp6 is required for proper somitogenesis and osteogenesis

2 October 2017

1 reference

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A transcriptional network in polycystic kidney disease

2 October 2017

1 reference

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Gene regulatory factors in pancreatic development

2 October 2017

1 reference

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Notch signaling controls multiple steps of pancreatic differentiation

2 October 2017

1 reference

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A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

2 October 2017

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Neurogenin3 activates the islet differentiation program while repressing its own expression

2 October 2017

1 reference

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Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development

2 October 2017

1 reference

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The transcription factor Sox9 has essential roles in successive steps of the chondrocyte differentiation pathway and is required for expression of Sox5 and Sox6

2 October 2017

1 reference

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Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop

2 October 2017

1 reference

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The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

2 October 2017

1 reference

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Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

2 October 2017

1 reference

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Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Regulation of the pancreatic pro-endocrine gene neurogenin3.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

An LDL-receptor-related protein mediates Wnt signalling in mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Notch gene expression during pancreatic organogenesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Cardiac defects and renal failure in mice with targeted mutations in Pkd2

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Control of endodermal endocrine development by Hes-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

The Notch-Hes pathway in mammalian neural development

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Notch signalling controls pancreatic cell differentiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Ngn3(+) endocrine progenitor cells control the fate and morphogenesis of pancreatic ductal epithelium

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Multiple, temporal-specific roles for HNF6 in pancreatic endocrine and ductal differentiation

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Jagged1 is a competitive inhibitor of Notch signaling in the embryonic pancreas

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

A highly efficient ligand-regulated Cre recombinase mouse line shows that LoxP recombination is position dependent

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Lineage tracing reveals the dynamic contribution of Hes1+ cells to the developing and adult pancreas.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Pancreatic exocrine duct cells give rise to insulin-producing beta cells during embryogenesis but not after birth

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Notch signaling controls liver development by regulating biliary differentiation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

A multipotent progenitor domain guides pancreatic organogenesis.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Temporal control of neurogenin3 activity in pancreas progenitors reveals competence windows for the generation of different endocrine cell types.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Notch signaling reveals developmental plasticity of Pax4(+) pancreatic endocrine progenitors and shunts them to a duct fate.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

A vHNF1/TCF2-HNF6 cascade regulates the transcription factor network that controls generation of pancreatic precursor cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Prox1 activity controls pancreas morphogenesis and participates in the production of "secondary transition" pancreatic endocrine cells.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Notch inhibits Ptf1 function and acinar cell differentiation in developing mouse and zebrafish pancreas

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Neurogenin 3-expressing progenitor cells in the gastrointestinal tract differentiate into both endocrine and non-endocrine cell types

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Conditional inactivation of Sox9: a mouse model for campomelic dysplasia.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

Conditional ablation of Notch signaling in pancreatic development

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3383226

The mesenchyme controls the timing of pancreatic beta-cell differentiation

5 December 2018

1 reference

12 December 2020

Rbp-j regulates expansion of pancreatic epithelial cells and their differentiation into exocrine cells during mouse development

1 reference

12 December 2020

Somatic inactivation of Pkd2 results in polycystic kidney disease

1 reference

12 December 2020

Notch/Rbp-j signaling prevents premature endocrine and ductal cell differentiation in the pancreas

1 reference

12 December 2020

Identifiers

DOI

10.1242/DEV.078634

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22675211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22675211%20AND%20SRC:MED&resulttype=core&format=json

3 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22675211%20AND%20SRC:MED&resulttype=core&format=json