ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain (Q36059093)

11 August 2017

ADP-Ribose Activates the TRPM2 Channel from the Sea Anemone Nematostella vectensis Independently of the NUDT9H Domain (English)

1 reference

Transient receptor potential cation channel subfamily M member 2

11 August 2017

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ligand-gated calcium channel activity

GOA release 2020-03-11

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GOA release 2020-03-11

Starlet sea anemone

object named as

Nematostella vectensis

1 reference

Frank J P Kühn

1

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11 August 2017

Cornelia Kühn

2

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11 August 2017

Mathis Winking

3

1 reference

11 August 2017

Daniel C Hoffmann

4

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11 August 2017

Andreas Lückhoff

5

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11 August 2017

language of work or name

English

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publication date

22 June 2016

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11 August 2017

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11 August 2017

11

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11 August 2017

e0158060

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11 August 2017

6

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Creative Commons Attribution 4.0 International

11 August 2017

start time

22 June 2016

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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Contribution of the S5-pore-S6 domain to the gating characteristics of the cation channels TRPM2 and TRPM8.

2 October 2017

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Two alleles of NF-kappaB in the sea anemone Nematostella vectensis are widely dispersed in nature and encode proteins with distinct activities

2 October 2017

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Intracellular calcium activates TRPM2 and its alternative spliced isoforms

2 October 2017

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The Poly(ADP-ribose) polymerase PARP-1 is required for oxidative stress-induced TRPM2 activation in lymphocytes

2 October 2017

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Three-dimensional reconstruction using transmission electron microscopy reveals a swollen, bell-shaped structure of transient receptor potential melastatin type 2 cation channel.

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Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization

2 October 2017

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The specific, submicromolar-Km ADP-ribose pyrophosphatase purified from human placenta is enzymically indistinguishable from recombinant NUDT9 protein, including a selectivity for Mn2+ as activating cation and increase in Km for ADP-ribose, both eli

2 October 2017

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Conserved cysteine residues in the pore region are obligatory for human TRPM2 channel function

2 October 2017

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Accumulation of free ADP-ribose from mitochondria mediates oxidative stress-induced gating of TRPM2 cation channels

2 October 2017

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Sites of the NUDT9-H domain critical for ADP-ribose activation of the cation channel TRPM2.

2 October 2017

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TRPM2 channel opening in response to oxidative stress is dependent on activation of poly(ADP-ribose) polymerase

2 October 2017

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The crystal structure and mutational analysis of human NUDT9

2 October 2017

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NUDT9, a member of the Nudix hydrolase family, is an evolutionarily conserved mitochondrial ADP-ribose pyrophosphatase.

2 October 2017

1 reference

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LTRPC2 Ca2+-permeable channel activated by changes in redox status confers susceptibility to cell death

2 October 2017

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Immunocyte Ca2+ influx system mediated by LTRPC2.

2 October 2017

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ADP-ribose gating of the calcium-permeable LTRPC2 channel revealed by Nudix motif homology

2 October 2017

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The MutT proteins or "Nudix" hydrolases, a family of versatile, widely distributed, "housecleaning" enzymes

2 October 2017

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Modulation of Diabetes-Induced Oxidative Stress, Apoptosis, and Ca2+ Entry Through TRPM2 and TRPV1 Channels in Dorsal Root Ganglion and Hippocampus of Diabetic Rats by Melatonin and Selenium

2 October 2017

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The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment.

23 September 2018

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Evolution of TRP channels inferred by their classification in diverse animal species

23 September 2018

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Surface expression and channel function of TRPM8 are cooperatively controlled by transmembrane segments S3 and S4.

23 September 2018

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Genomic survey of candidate stress-response genes in the estuarine anemone Nematostella vectensis

23 September 2018

1 reference

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Evolutionary determinants of divergent calcium selectivity of TRPM channels.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917252

Modulation of the Ca2 permeable cation channel TRPV4 by cytochrome P450 epoxygenases in vascular endothelium.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917252

Activation of the cation channel long transient receptor potential channel 2 (LTRPC2) by hydrogen peroxide. A splice variant reveals a mode of activation independent of ADP-ribose.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4917252

10.1371/JOURNAL.PONE.0158060

23 September 2018

Identifiers

DOI

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11 August 2017

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11 August 2017

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