Metabolic mechanisms of tumor resistance to T cell effector function (Q36075227)

12 August 2017

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title

Metabolic mechanisms of tumor resistance to T cell effector function (English)

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12 August 2017

Candace M Cham

1

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12 August 2017

Thomas F Gajewski

series ordinal

2

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12 August 2017

publication date

1 January 2005

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12 August 2017

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12 August 2017

volume

31

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12 August 2017

issue

2

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12 August 2017

page(s)

107-118

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Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase

12 August 2017

cites work

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12 December 2020

Nitric oxide and peroxynitrite interactions with mitochondria

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12 December 2020

Inhibition of indoleamine 2,3-dioxygenase activity in IFN-gamma stimulated astroglioma cells decreases intracellular NAD levels

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12 December 2020

Role of TGF-beta in immune-evasion of cancer

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12 December 2020

Genetic ablation of inducible nitric oxide synthase decreases mouse lung tumorigenesis.

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12 December 2020

c-Myc is required for the glucose-mediated induction of metabolic enzyme genes

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12 December 2020

Role of oxygen in T cell-mediated cytolysis

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12 December 2020

Th1/Th2-regulated expression of arginase isoforms in murine macrophages and dendritic cells

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12 December 2020

Aerobic glycolysis by proliferating cells: a protective strategy against reactive oxygen species.

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12 December 2020

Evidence for a tumoral immune resistance mechanism based on tryptophan degradation by indoleamine 2,3-dioxygenase

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12 December 2020

Role of nitric oxide in tumour progression: lessons from human tumours

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12 December 2020

The unique physiology of solid tumors: opportunities (and problems) for cancer therapy.

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12 December 2020

Causes and consequences of tumour acidity and implications for treatment

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12 December 2020

Role of oxygen vs. glucose in energy metabolism in a mammary carcinoma perfused ex vivo: direct measurement by 31P NMR.

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12 December 2020

The role of nitric oxide in cancer

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12 December 2020

L-arginine consumption by macrophages modulates the expression of CD3 zeta chain in T lymphocytes

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12 December 2020

Nitric oxide inhibits indoleamine 2,3-dioxygenase activity in interferon-gamma primed mononuclear phagocytes.

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12 December 2020

Increased vaccine-specific T cell frequency after peptide-based vaccination correlates with increased susceptibility to in vitro stimulation but does not lead to tumor regression

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12 December 2020

Metastatic melanoma cells escape from immunosurveillance through the novel mechanism of releasing nitric oxide to induce dysfunction of immunocytes

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12 December 2020

Inducible nitric oxide synthase (iNOS) expression and its prognostic value in prostate cancer

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12 December 2020

Suppression of tumorigenicity and metastasis of human renal carcinoma cells by infection with retroviral vectors harboring the murine inducible nitric oxide synthase gene

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12 December 2020

Arginase and ornithine, as markers in human non-small cell lung carcinoma

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12 December 2020

Sustained nitric oxide production in macrophages requires the arginine transporter CAT2

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12 December 2020

Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells

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12 December 2020

Natural killer cells and nitric oxide.

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12 December 2020

Calcium signaling mechanisms in T lymphocytes

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12 December 2020

Alpha-difluoromethylornithine (DFMO) as a potent arginase activity inhibitor in human colon carcinoma cells

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12 December 2020

CAT2-mediated L-arginine transport and nitric oxide production in activated macrophages.

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12 December 2020

Role of intracellular pH in proliferation, transformation, and apoptosis

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12 December 2020

Tryptophan catabolism and regulation of adaptive immunity

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

Expression of nitric oxide synthase, cyclooxygenase, and p53 in different stages of human gastric cancer

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12 December 2020

Immunity to cancer: attack and escape in T lymphocyte-tumor cell interaction

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12 December 2020

Analysis of the mechanisms of human cytotoxic T lymphocyte response inhibition by NO.

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12 December 2020

Pattern of recruitment of immunoregulatory antigen-presenting cells in malignant melanoma.

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12 December 2020

Nitric oxide inhibits apoptosis via AP-1-dependent CD95L transactivation

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12 December 2020

The CD28 signaling pathway regulates glucose metabolism

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12 December 2020

Arginine availability, arginase, and the immune response

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12 December 2020

Serum arginase level in patients with gastric cancer

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12 December 2020

Energy metabolism and T-cell-mediated cytolysis. I. Synergism between inhibitors of respiration and glycolysis

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12 December 2020

Human placental indoleamine 2,3-dioxygenase: cellular localization and characterization of an enzyme preventing fetal rejection.

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12 December 2020

Transcriptional regulation of genes encoding glycolytic enzymes by hypoxia-inducible factor 1

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12 December 2020

Inhibition of T cell proliferation by macrophage tryptophan catabolism

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12 December 2020

Direct demonstration of negative regulation of tumor growth and metastasis by host-inducible nitric oxide synthase

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12 December 2020

Deficiency of transporter for antigen presentation (TAP) in tumor cells allows evasion of immune surveillance and increases tumorigenesis.

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12 December 2020

The role of IL-10 and TGF-beta in the differentiation and effector function of T regulatory cells

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12 December 2020

Indoleamine 2,3-dioxygenase production by human dendritic cells results in the inhibition of T cell proliferation

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12 December 2020

What Is the Evidence That Tumors Are Angiogenesis Dependent?

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12 December 2020

Immune and metabolic effects of arginine in the surgical patient

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12 December 2020

Macrophage-derived nitric oxide regulates T cell activation via reversible disruption of the Jak3/STAT5 signaling pathway

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12 December 2020

Does nitric oxide modulate mitochondrial energy generation and apoptosis?

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12 December 2020

Signaling defects in T lymphocytes of patients with malignancy

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12 December 2020

T cell apoptosis by tryptophan catabolism

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12 December 2020

The metabolic basis of arginine nutrition and pharmacotherapy

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12 December 2020

Nitric oxide and the regulation of gene expression

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12 December 2020

THE role of indoleamine 2,3-dioxygenase in the anti-tumour activity of human interferon-γin vivo

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12 December 2020

Inducible nitric oxide synthase and nitrotyrosine in human metastatic melanoma tumors correlate with poor survival

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12 December 2020

Transport of molecules, particles, and cells in solid tumors

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12 December 2020

Antiapoptotic role of endogenous nitric oxide in human melanoma cells

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12 December 2020

Using positron emission tomography with [(18)F]FDG to predict tumor behavior in experimental colorectal cancer

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12 December 2020

Lymphocyte function in wound healing and following injury

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12 December 2020

Hypoxia regulates expression and activity of Kv1.3 channels in T lymphocytes: a possible role in T cell proliferation.

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12 December 2020

Role of nitric oxide in tumour progression with special reference to a murine breast cancer model

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12 December 2020

The contribution of lactic acid to acidification of tumours: studies of variant cells lacking lactate dehydrogenase

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12 December 2020

Functional dissociation between local and systemic immune response during anti-melanoma peptide vaccination

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12 December 2020

Regulatory role of arginase I and II in nitric oxide, polyamine, and proline syntheses in endothelial cells

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12 December 2020

Tryptophan deprivation sensitizes activated T cells to apoptosis prior to cell division

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12 December 2020

Lymphocytic infiltration and cytotoxicity under hypoxic conditions in the EMT6 mouse mammary tumor

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12 December 2020

Reduced recognition of metastatic melanoma cells by autologous MART-1 specific CTL: relationship to TAP expression

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12 December 2020

Nutritional pharmacology and malignant disease: a therapeutic modality in patients with cancer

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12 December 2020

Arginase activity in human breast cancer cell lines: N(omega)-hydroxy-L-arginine selectively inhibits cell proliferation and induces apoptosis in MDA-MB-468 cells

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12 December 2020

Tryptophan-derived catabolites are responsible for inhibition of T and natural killer cell proliferation induced by indoleamine 2,3-dioxygenase.

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12 December 2020

Interleukin-12 and interleukin-18 induce indoleamine 2,3-dioxygenase (IDO) activity in human osteosarcoma cell lines independently from interferon-gamma

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12 December 2020

Cancer-induced defective cytotoxic T lymphocyte effector function: another mechanism how antigenic tumors escape immune-mediated killing

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12 December 2020

'The metabolism of tumours': 70 years later

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12 December 2020

Induction of antigen-specific T cell anergy: An early event in the course of tumor progression

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12 December 2020

The role of the Crabtree effect and an endogenous fuel in the energy metabolism of resting and proliferating thymocytes

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12 December 2020

Selective blockers of voltage-gated K+ channels depolarize human T lymphocytes: mechanism of the antiproliferative effect of charybdotoxin

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12 December 2020

Redox signaling: nitrosylation and related target interactions of nitric oxide

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12 December 2020

Impaired immune responses and altered peptide repertoire in tapasin-deficient mice

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12 December 2020

Association of increased immunostaining for inducible nitric oxide synthase and nitrotyrosine with fibroblast growth factor transformation in pancreatic cancer

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12 December 2020

Indoleamine 2,3-dioxygenase contributes to tumor cell evasion of T cell-mediated rejection.

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12 December 2020

Gene array and protein expression profiles suggest post-transcriptional regulation during CD8+ T cell differentiation

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12 December 2020

Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production

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12 December 2020

Hypoxia affects cytokine production and proliferative responses by human peripheral mononuclear cells

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12 December 2020

Immune suppression by recombinant interleukin (rIL)-12 involves interferon gamma induction of nitric oxide synthase 2 (iNOS) activity: inhibitors of NO generation reveal the extent of rIL-12 vaccine adjuvant effect

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12 December 2020

Energy metabolism and T-cell-mediated cytolysis. II. Selective inhibition of cytolysis by 2-deoxy-D-glucose

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12 December 2020

Cutting edge: spontaneous rejection of poorly immunogenic P1.HTR tumors by Stat6-deficient mice

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12 December 2020

Studies with glycolysis-deficient cells suggest that production of lactic acid is not the only cause of tumor acidity

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12 December 2020

Differential activation of mitogen-activated protein kinases by nitric oxide-related species

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12 December 2020

Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice

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12 December 2020

Increasing tumor antigen expression overcomes "ignorance" to solid tumors via crosspresentation by bone marrow-derived stromal cells

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12 December 2020

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

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12 December 2020

Cutting edge: STAT6-deficient mice have enhanced tumor immunity to primary and metastatic mammary carcinoma

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12 December 2020

Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade

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12 December 2020

Mammary tumor latency is increased in mice lacking the inducible nitric oxide synthase

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12 December 2020

Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions

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12 December 2020

Influence of nitric oxide synthase II gene disruption on tumor growth and metastasis.

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12 December 2020

Identifiers

DOI

10.1385/IR:31:2:107

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Dimensions Publication ID

12 August 2017

1043179067

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