Heteronemin Is a Novel c-Met/STAT3 Inhibitor Against Advanced Prostate Cancer Cells. (Q36077939)

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18 March 2020

title

Heteronemin Is a Novel c-Met/STAT3 Inhibitor Against Advanced Prostate Cancer Cells (English)

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18 March 2020

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6

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author name string

Jian-Ching Wu

1

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18 March 2020

Chiang-Ting Wang

2

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18 March 2020

Han-Chun Hung

3

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18 March 2020

Wen-Jeng Wu

4

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18 March 2020

Deng-Chyang Wu

5

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18 March 2020

Ping-Jyun Sung

7

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18 March 2020

Yu-Wei Chou

8

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18 March 2020

Zhi-Hong Wen

9

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18 March 2020

Ming-Hong Tai

10

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18 March 2020

publication date

15 July 2016

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18 March 2020

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18 March 2020

volume

76

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issue

16

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page(s)

1469-1483

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Molecular biology of the androgen receptor

18 March 2020

cites work

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Biology of progressive, castration-resistant prostate cancer: directed therapies targeting the androgen-receptor signaling axis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Castration-resistant prostate cancer: systemic therapy in 2012

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Androgen Receptor Gene Amplification and Protein Expression in Recurrent Prostate Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Treatment-dependent androgen receptor mutations in prostate cancer exploit multiple mechanisms to evade therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

The transcriptional co-activator cAMP response element-binding protein-binding protein is expressed in prostate cancer and enhances androgen- and anti-androgen-induced androgen receptor function

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Expression and function of androgen receptor coactivators in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Genome-wide expression profiling reveals transcriptomic variation and perturbed gene networks in androgen-dependent and androgen-independent prostate cancer cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

From Tpr-Met to Met, tumorigenesis and tubes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Invasive growth: a MET-driven genetic programme for cancer and stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Hypoxia can induce c-Met expression in glioma cells and enhance SF/HGF-induced cell migration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

The androgen receptor negatively regulates the expression of c-Met: implications for a novel mechanism of prostate cancer progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Wild-type p53 controls cell motility and invasion by dual regulation of MET expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Prostate cancer and the met hepatocyte growth factor receptor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Prostate cancer stem-like cells/cancer-initiating cells have an autocrine system of hepatocyte growth factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Activation of c-MET induces a stem-like phenotype in human prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Stat3 promotes metastatic progression of prostate cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

The STATs of cancer--new molecular targets come of age

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Small molecule inhibitors of STAT3 for cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Signal transducer and activator of transcription 3 (STAT3) activation in prostate cancer: Direct STAT3 inhibition induces apoptosis in prostate cancer lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Inhibition of STAT3 signaling targets both tumor-initiating and differentiated cell populations in prostate cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Application of the PM6 semi-empirical method to modeling proteins enhances docking accuracy of AutoDock

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Merck molecular force field. I. Basis, form, scope, parameterization, and performance of MMFF94

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Minimization by Random Search Techniques

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Antiproliferative activity of novel imidazopyridine derivatives on castration-resistant human prostate cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Steap4 attenuates high glucose and S100B-induced effects in mesangial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Systemic pro-opiomelanocortin expression induces melanogenic differentiation and inhibits tumor angiogenesis in established mouse melanoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Proopiomelanocortin gene delivery induces apoptosis in melanoma through NADPH oxidase 4-mediated ROS generation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1α.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

STAT3 as a target for inducing apoptosis in solid and hematological tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

In vitro characterisation of the anti-intravasative properties of the marine product heteronemin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Heteronemin, a marine sponge terpenoid, targets TDP-43, a key factor in several neurodegenerative disorders

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Heteronemin, a Spongean Sesterterpene, Induces Cell Apoptosis and Autophagy in Human Renal Carcinoma Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Understanding the mechanisms of androgen deprivation resistance in prostate cancer at the molecular level

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Targeting the HGF/c-MET pathway in hepatocellular carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

Revisiting STAT3 signalling in cancer: new and unexpected biological functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FPROS.23230

21 January 2018

Identifiers

DOI

10.1002/PROS.23230

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27416770%20AND%20SRC:MED&resulttype=core&format=json

18 March 2020

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