Gene therapy progress and prospects: targeted gene repair (Q36091278)

12 August 2017

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title

Gene therapy progress and prospects: targeted gene repair (English)

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12 August 2017

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Parekh-Olmedo H

1

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12 August 2017

Ferrara L

series ordinal

2

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12 August 2017

Brachman E

series ordinal

3

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12 August 2017

Kmiec EB

series ordinal

4

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12 August 2017

1 April 2005

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12 August 2017

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12 August 2017

12

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12 August 2017

8

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12 August 2017

639-646

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https://scigraph.springernature.com/pub.10.1038/sj.gt.3302511

12 August 2017

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cites work

Progress and problems with the use of viral vectors for gene therapy

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

The development and regulation of gene repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Genetic engineering using homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Recombineering with overlapping single-stranded DNA oligonucleotides: testing a recombination intermediate

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

DNA pairing is an important step in the process of targeted nucleotide exchange

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Rad51p and Rad54p, but not Rad52p, elevate gene repair in Saccharomyces cerevisiae directed by modified single-stranded oligonucleotide vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Nuclear extracts promote gene correction and strand pairing of oligonucleotides to the homologous plasmid

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Optimising gene repair strategies in cell culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Branched oligonucleotides induce in vivo gene conversion of a mutated EGFP reporter

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Enhanced oligonucleotide-directed gene targeting in mammalian cells following treatment with DNA damaging agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Camptothecin enhances the frequency of oligonucleotide-directed gene repair in mammalian cells by inducing DNA damage and activating homologous recombination

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Design of a nonviral vector for site-selective, efficient integration into the human genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Genome engineering using site-specific recombinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Chimeric recombinases with designed DNA sequence recognition

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Mechanisms underlying targeted gene correction using chimeric RNA/DNA and single-stranded DNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Targeted gene modification in mismatch-repair-deficient embryonic stem cells by single-stranded DNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Simultaneous targeted alteration of the tyrosinase and c-kit genes by single-stranded oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Functional correction of episomal mutations with short DNA fragments and RNA-DNA oligonucleotides.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Reaction parameters of targeted gene repair in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Oligonucleotide-directed single-base DNA alterations in mouse embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

A comparison of gene repair strategies in cell culture using a lacZ reporter system

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Targeted gene correction of hprt mutations by 45 base single-stranded oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Concurrent targeted exchange of three bases in mammalian hprt by oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Sequence-specific modification of genomic DNA by small DNA fragments

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Therapeutic application of chimeric RNA/DNA oligonucleotide based gene therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Correction/mutation of acid α-D-glucosidase gene by modified single-stranded oligonucleotides: in vitro and in vivo studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Targeted conversion of the transthyretin gene in vitro and in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

A LacZ-based transgenic mouse for detection of somatic gene repair events in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Transcription affects formation and processing of intermediates in oligonucleotide-mediated gene alteration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

DNA replication and transcription direct a DNA strand bias in the process of targeted gene repair in mammalian cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Gene repair in mammalian cells is stimulated by the elongation of S phase and transient stalling of replication forks.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Oligonucleotide-directed mutagenesis and targeted gene correction: a mechanistic point of view

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Unmodified oligodeoxynucleotides require single-strandedness to induce targeted repair of a chromosomal EGFP gene

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

The effect of hydroxyurea and trichostatin a on targeted nucleotide exchange in yeast and Mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Cell cycle modulation of gene targeting by a triple helix-forming oligonucleotide.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Mismatch repair and DNA damage signalling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Association of p53 and MSH2 with recombinative repair complexes during S phase

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Targeted beta-globin gene conversion in human hematopoietic CD34(+ )and Lin(-)CD38(-)cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Checking on the fork: the DNA-replication stress-response pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Regulation of DNA replication by ATR: signaling in response to DNA intermediates

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Implications of cell cycle progression on functional sequence correction by short single-stranded DNA oligonucleotides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Nuclease Activity of Saccharomyces cerevisiae Mre11 Functions in Targeted Nucleotide Alteration

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Strand bias in oligonucleotide-mediated dystrophin gene editing

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Restoration of dystrophin expression in mdx muscle cells by chimeraplast-mediated exon skipping

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

Site-specific genomic integration produces therapeutic Factor IX levels in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

inferred from DOI database lookup

7 January 2021

based on heuristic

DNA mismatch repair and cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.GT.3302511

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/SJ.GT.3302511

1 reference

12 August 2017

1 reference