Notch signaling, brain development, and human disease (Q36092136)

12 August 2017

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title

Notch signaling, brain development, and human disease (English)

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12 August 2017

Joseph L Lasky

1

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12 August 2017

Hong Wu

series ordinal

2

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12 August 2017

language of work or name

English

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publication date

6 April 2005

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12 August 2017

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12 August 2017

57

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12 August 2017

5 Pt 2

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12 August 2017

104R-109R

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https://scigraph.springernature.com/pub.10.1203/01.pdr.0000159632.70510.3d

12 August 2017

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cites work

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Notch signaling in development and disease

21 January 2018

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The role of Notch in tumorigenesis: oncogene or tumour suppressor?

21 January 2018

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LIN-12/Notch signaling: lessons from worms and flies

21 January 2018

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Notch signaling: cell fate control and signal integration in development

21 January 2018

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Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta.

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Notch1 signaling promotes the maturation of CD4 and CD8 SP thymocytes

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

An activated form of Notch influences the choice between CD4 and CD8 T cell lineages

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Notch signaling in the integrated control of keratinocyte growth/differentiation and tumor suppression

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

The role of notch in promoting glial and neural stem cell fates

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Radial glial identity is promoted by Notch1 signaling in the murine forebrain

21 January 2018

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Transient Notch activation initiates an irreversible switch from neurogenesis to gliogenesis by neural crest stem cells

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

The lin-12 locus specifies cell fates in Caenorhabditis elegans

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Recruitment of cell groups through Delta/Notch signalling during spider neurogenesis.

21 January 2018

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Notch1 is essential for postimplantation development in mice.

21 January 2018

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Novel Notch alleles reveal a Deltex-dependent pathway repressing neural fate.

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

New alleles of Notch draw a blueprint for multifunctionality.

21 January 2018

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Up a notch: instructing gliogenesis

21 January 2018

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Hes genes regulate size, shape and histogenesis of the nervous system by control of the timing of neural stem cell differentiation

21 January 2018

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Notch pathway molecules are essential for the maintenance, but not the generation, of mammalian neural stem cells

21 January 2018

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Primitive neural stem cells from the mammalian epiblast differentiate to definitive neural stem cells under the control of Notch signaling

21 January 2018

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Distinct neural stem cells proliferate in response to EGF and FGF in the developing mouse telencephalon.

21 January 2018

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Notch1 and Notch3 instructively restrict bFGF-responsive multipotent neural progenitor cells to an astroglial fate

21 January 2018

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Glial specification in the vertebrate neural tube

21 January 2018

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rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Regeneration of a germinal layer in the adult mammalian brain

21 January 2018

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Neuronal or glial progeny: regional differences in radial glia fate

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Mapping spatio-temporal activation of Notch signaling during neurogenesis and gliogenesis in the developing mouse brain

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Alzheimer's disease: beta-Amyloid protein and tau.

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Notch and Presenilin: regulated intramembrane proteolysis links development and degeneration.

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Nuclear Notch1 signaling and the regulation of dendritic development

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Molecular control of cortical dendrite development

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Presenilin is required for proper morphology and function of neurons in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Requirement of Notch in adulthood for neurological function and longevity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Notch is required for long-term memory in Drosophila

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Learning and memory deficits in Notch mutant mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Involvement of Notch signaling in hippocampal synaptic plasticity

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Association between presenilin-1 -48C/T polymorphism and Down's syndrome

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Down's syndrome: a genetic disorder in biobehavioral perspective

21 January 2018

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https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

A mouse model for Down syndrome exhibits learning and behaviour deficits.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Activating mutations of NOTCH1 in human T cell acute lymphoblastic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Notch3 mutations in CADASIL, a hereditary adult-onset condition causing stroke and dementia

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

The NOTCH4 locus is associated with susceptibility to schizophrenia

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Clinical Features of CADASIL.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

The ectodomain of the Notch3 receptor accumulates within the cerebrovasculature of CADASIL patients

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Transgenic mice expressing mutant Notch3 develop vascular alterations characteristic of cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

The pathogenesis of CADASIL: an update

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

A CADASIL-mutated Notch 3 receptor exhibits impaired intracellular trafficking and maturation but normal ligand-induced signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

CADASIL Notch3 mutant proteins localize to the cell surface and bind ligand

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Pathogenic mutations associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy differently affect Jagged1 binding and Notch3 activity via the RBP/JK signaling Pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

CADASIL-associated Notch3 mutations have differential effects both on ligand binding and ligand-induced Notch3 receptor signaling through RBP-Jk

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Family-based association study of the NOTCH4 gene in schizophrenia using Japanese and Chinese samples.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Modest evidence for linkage and possible confirmation of association between NOTCH4 and schizophrenia in a large Veterans Affairs Cooperative Study sample

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

NOTCH4 and the frontal lobe in schizophrenia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Focal cortical dysplasia: a neuropathological and developmental perspective

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Presenilin-1 deficiency leads to loss of Cajal-Retzius neurons and cortical dysplasia similar to human type 2 lissencephaly

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Expression of the neural RNA-binding protein Musashi1 in human gliomas

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Human cortical glial tumors contain neural stem-like cells expressing astroglial and neuronal markers in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Cancerous stem cells can arise from pediatric brain tumors

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Identification of differentially expressed and developmentally regulated genes in medulloblastoma using suppression subtraction hybridization.

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

Disturbance of Notch-1 and Wnt signalling proteins in neuroglial balloon cells and abnormal large neurons in focal cortical dysplasia in human cortex

21 January 2018

1 reference

https://api.crossref.org/works/10.1203%2F01.PDR.0000159632.70510.3D

10.1203/01.PDR.0000159632.70510.3D

21 January 2018

Identifiers

DOI

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Dimensions Publication ID

12 August 2017

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1 reference