siRNA-mediated inhibition of angiogenesis (Q36099464)

12 August 2017

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title

siRNA-mediated inhibition of angiogenesis (English)

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12 August 2017

Raymond M Schiffelers

series ordinal

1

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12 August 2017

Inge van Rooy

series ordinal

2

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12 August 2017

Gert Storm

series ordinal

3

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12 August 2017

language of work or name

English

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publication date

1 March 2005

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Expert Opinion on Biological Therapy

12 August 2017

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12 August 2017

5

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12 August 2017

3

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12 August 2017

359-368

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Introduction of a Chimeric Chalcone Synthase Gene into Petunia Results in Reversible Co-Suppression of Homologous Genes in trans

12 August 2017

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Heritable gene silencing in Drosophila using double-stranded RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

RNA interference: biology, mechanism, and applications

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Gene silencing mediated by small interfering RNAs in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Characteristics of RNA silencing in plants: similarities and differences across kingdoms

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

RNA-mediated gene silencing: mechanisms and its therapeutic applications.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Dicers at RISC; the mechanism of RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Distinct roles for Argonaute proteins in small RNA-directed RNA cleavage pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

R2D2 leads the silencing trigger to mRNA's death star.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Single-stranded antisense siRNAs guide target RNA cleavage in RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Induction of DNA methylation and gene silencing by short interfering RNAs in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Small interfering RNA-induced transcriptional gene silencing in human cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

The dsRNA binding protein family: critical roles, diverse cellular functions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

RNA interference and double-stranded-RNA-activated pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Nonspecific, concentration-dependent stimulation and repression of mammalian gene expression by small interfering RNAs (siRNAs).

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Activation of the interferon system by short-interfering RNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Transport of dsRNA into cells by the transmembrane protein SID-1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

On the role of RNA amplification in dsRNA-triggered gene silencing

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Spreading silence with Sid

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

RNAi As a tool for understanding germline development in Caenorhabditis elegans: uses and cautions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Specific interference by ingested dsRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Exposing oncogenic dependencies for cancer drug target discovery and validation using RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

RNAi microarray analysis in cultured mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Adenoviral vectors expressing siRNAs for discovery and validation of gene function

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

siRNAs: applications in functional genomics and potential as therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Therapeutic potential of retroviral RNAi vectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Angiogenesis inhibitors: current & future directions

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Challenges for RNAi in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

The design and exogenous delivery of siRNA for post-transcriptional gene silencing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Small RNA: can RNA interference be exploited for therapy?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Role of growth factors and the wound healing response in age-related macular degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

The role of growth factors in the pathogenesis of diabetic retinopathy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Endothelial cell phenotypes in the rheumatoid synovium: activated, angiogenic, apoptotic and leaky

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Angiogenesis as an immunopharmacologic target in inflammation and cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Molecular diagnosis of tumor angiogenesis and anti-angiogenic cancer therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Role of growth factors and their receptors in proliferation of microvascular endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Role of thrombin in angiogenesis and tumor progression

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Integrins: roles in cancer development and as treatment targets

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Endothelial-pericyte interactions in angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Lymphatics at the crossroads of angiogenesis and lymphangiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Molecular mechanisms of lymphangiogenesis in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Sphingosine kinase mediates vascular endothelial growth factor-induced activation of ras and mitogen-activated protein kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

CD13/APN transcription is induced by RAS/MAPK-mediated phosphorylation of Ets-2 in activated endothelial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Vector-based RNAi, a novel tool for isoform-specific knock-down of VEGF and anti-angiogenesis gene therapy of cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Essential role of junctional adhesion molecule-1 in basic fibroblast growth factor-induced endothelial cell migration.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Adaptor protein Crk is required for ephrin-B1-induced membrane ruffling and focal complex assembly of human aortic endothelial cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

EndoPDI, a novel protein-disulfide isomerase-like protein that is preferentially expressed in endothelial cells acts as a stress survival factor

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Desmoplakin is required for microvascular tube formation in culture

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Automatic identification of subcellular phenotypes on human cell arrays

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

High-throughput RNAi in Caenorhabditis elegans: genome-wide screens and functional genomics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

VEGF-receptor inhibitors for anti-angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

VEGF signalling: integration and multi-tasking in endothelial cell biology

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

From the cradle to the clinic: VEGF in developmental, physiological, and pathological angiogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

A novel low molecular weight VEGF receptor-binding antagonist, VGA1102, inhibits the function of VEGF and in vivo tumor growth

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Inhibition of vascular endothelial growth factor (VEGF) signaling in cancer causes loss of endothelial fenestrations, regression of tumor vessels, and appearance of basement membrane ghosts

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Inhibition of cathepsin B and MMP-9 gene expression in glioblastoma cell line via RNA interference reduces tumor cell invasion, tumor growth and angiogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

A small interfering RNA targeting vascular endothelial growth factor as cancer therapeutics

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Cancer siRNA therapy by tumor selective delivery with ligand-targeted sterically stabilized nanoparticle

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Inhibition of ocular angiogenesis by siRNA targeting vascular endothelial growth factor pathway genes: therapeutic strategy for herpetic stromal keratitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Expression profiling reveals off-target gene regulation by RNAi

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Many commonly used siRNAs risk off-target activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Lentiviral-mediated RNA interference

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Retrovirus-delivered siRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Use of adeno-associated viral vector for delivery of small interfering RNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

siRNA function in RNAi: a chemical modification analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Tolerance for mutations and chemical modifications in a siRNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

In vivo activity of nuclease-resistant siRNAs

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

Genes Required for Systemic RNA Interference in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14712598.5.3.359

21 January 2018

Identifiers

DOI

10.1517/14712598.5.3.359

1 reference

12 August 2017

1 reference