Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation (Q36100130)

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English	Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation	scientific article

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scholarly article

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Europe PubMed Central

12 August 2017

Chronic TLR Stimulation Controls NLRP3 Inflammasome Activation through IL-10 Mediated Regulation of NLRP3 Expression and Caspase-8 Activation (English)

1 reference

Europe PubMed Central

12 August 2017

toll-like receptor

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inflammasome complex

1 reference

based on heuristic

inferred from title

Terrence L Geiger

object named as

Terrence L Geiger

5

0 references

object named as

Prajwal Gurung

1

0 references

Thirumala-Devi Kanneganti

object named as

Thirumala-Devi Kanneganti

6

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author name string

Bofeng Li

2

1 reference

Europe PubMed Central

12 August 2017

R K Subbarao Malireddi

3

1 reference

Europe PubMed Central

12 August 2017

Mohamed Lamkanfi

4

1 reference

Europe PubMed Central

12 August 2017

language of work or name

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publication date

28 September 2015

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Europe PubMed Central

12 August 2017

Scientific Reports

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Europe PubMed Central

12 August 2017

5

1 reference

Europe PubMed Central

12 August 2017

14488

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Europe PubMed Central

12 August 2017

copyright license

Creative Commons Attribution 4.0 International

28 September 2015

1 reference

April 2022 Public Data File from Crossref

copyright status

0 references

https://scigraph.springernature.com/pub.10.1038/srep14488

0 references

Interleukin-10 receptor signaling in innate immune cells regulates mucosal immune tolerance and anti-inflammatory macrophage function

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

FADD and caspase-8 mediate priming and activation of the canonical and noncanonical Nlrp3 inflammasomes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

IL-10 modulates DSS-induced colitis through a macrophage-ROS-NO axis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

The calcium-sensing receptor regulates the NLRP3 inflammasome through Ca2+ and cAMP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Toll or interleukin-1 receptor (TIR) domain-containing adaptor inducing interferon-β (TRIF)-mediated caspase-11 protease production integrates Toll-like receptor 4 (TLR4) protein- and Nlrp3 inflammasome-mediated host defense against enteropathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Dissecting negative regulation of Toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Role of the nlrp3 inflammasome in microbial infection.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

The inflammasomes: mechanisms of activation and function

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Inflammatory bowel disease and mutations affecting the interleukin-10 receptor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Interleukin 10 acts on regulatory T cells to maintain expression of the transcription factor Foxp3 and suppressive function in mice with colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Toll-like receptors (TLRs) and Nod-like receptors (NLRs) in inflammatory disorders.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Cutting edge: NF-kappaB activating pattern recognition and cytokine receptors license NLRP3 inflammasome activation by regulating NLRP3 expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Modulation of the intestinal microbiota alters colitis-associated colorectal cancer susceptibility

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Chronic stimulation of Nod2 mediates tolerance to bacterial products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Cryopyrin activates the inflammasome in response to toxins and ATP

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Bacterial RNA and small antiviral compounds activate caspase-1 through cryopyrin/Nalp3

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

New insights into the molecular mechanism of interleukin-10-mediated immunosuppression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Differential activation of the inflammasome by caspase-1 adaptors ASC and Ipaf

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

NALP3 forms an IL-1beta-processing inflammasome with increased activity in Muckle-Wells autoinflammatory disorder

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

CpG DNA induces self and cross-hyporesponsiveness of RAW264.7 cells in response to CpG DNA and lipopolysaccharide: alterations in IL-1 receptor-associated kinase expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Cutting edge: a novel Toll/IL-1 receptor domain-containing adapter that preferentially activates the IFN-beta promoter in the Toll-like receptor signaling

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Gram-negative flagellin-induced self-tolerance is associated with a block in interleukin-1 receptor-associated kinase release from toll-like receptor 5.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Toll-like receptors and innate immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Human macrophage activation programs induced by bacterial pathogens

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Reprogramming of the macrophage transcriptome in response to interferon-gamma and Mycobacterium tuberculosis: signaling roles of nitric oxide synthase-2 and phagocyte oxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Interleukin-10 targets p38 MAPK to modulate ARE-dependent TNF mRNA translation and limit intestinal pathology.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

A human homologue of the Drosophila Toll protein signals activation of adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

The nonspecific nature of endotoxin tolerance

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Interleukin-10-deficient mice develop chronic enterocolitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Prolonged expression of lipopolysaccharide (LPS)-induced inflammatory genes in whole blood requires continual exposure to LPS.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 October 2017

Interleukin-10 regulates the inflammasome-driven augmentation of inflammatory arthritis and joint destruction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 July 2018

Inflammasome activation has an important role in the development of spontaneous colitis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

2 July 2018

Direct proteomic quantification of the secretome of activated immune cells.

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23 September 2018

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4585974

23 September 2018

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

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23 September 2018

Type I Interferon Inhibits Interleukin-1 Production and Inflammasome Activation

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21 January 2018

Macrophage-restricted interleukin-10 receptor deficiency, but not IL-10 deficiency, causes severe spontaneous colitis

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21 October 2018

https://api.crossref.org/works/10.1038%2FSREP14488

21 January 2018

Kinetics of TNF, IL-6, and IL-8 gene expression in LPS-stimulated human whole blood

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12 December 2020

based on heuristic

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Protective effect of tumor necrosis factor-alpha against subsequent endotoxemia in mice is mediated, in part, by interleukin-10

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https://pubmed.ncbi.nlm.nih.gov/26412089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin (IL)-10 inhibits nuclear factor kappa B (NF kappa B) activation in human monocytes. IL-10 and IL-4 suppress cytokine synthesis by different mechanisms

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Synergy and cross-tolerance between toll-like receptor (TLR) 2- and TLR4-mediated signaling pathways

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Interleukin-1 beta, interleukin-18, and the interleukin-1 beta converting enzyme

1 reference

https://pubmed.ncbi.nlm.nih.gov/26412089

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SREP14488

1 reference

Europe PubMed Central

12 August 2017

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1 reference

Europe PubMed Central

12 August 2017

1 reference

Europe PubMed Central

12 August 2017

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