Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues (Q36101745)

12 August 2017

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title

Biochemical and cellular mechanisms of mammalian CDK inhibitors: a few unresolved issues (English)

1 reference

12 August 2017

Xin-Hai Pei

1

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PubMed ID

15838515

12 August 2017

Yue Xiong

series ordinal

2

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PubMed ID

15838515

12 August 2017

language of work or name

English

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publication date

1 April 2005

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12 August 2017

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12 August 2017

24

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12 August 2017

17

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12 August 2017

2787-2795

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1208611

12 August 2017

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cites work

Differential interaction of the cyclin-dependent kinase (Cdk) inhibitor p27Kip1 with cyclin A-Cdk2 and cyclin D2-Cdk4.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Regulation of the human cyclin-dependent kinase inhibitor p18INK4c by the transcription factors E2F1 and Sp1

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Distinct roles for E2F proteins in cell growth control and apoptosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Cdk-interacting protein 1 directly binds with proliferating cell nuclear antigen and inhibits DNA replication catalyzed by the DNA polymerase delta holoenzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Deletion of the p27Kip1 gene restores normal development in cyclin D1-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Mice lacking JunB are osteopenic due to cell-autonomous osteoblast and osteoclast defects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Growth suppression by p16ink4 requires functional retinoblastoma protein

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Menin and MLL cooperatively regulate expression of cyclin-dependent kinase inhibitors

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Association of Stat3-dependent transcriptional activation of p19INK4D with IL-6-induced growth arrest

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screen.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Stat3-dependent induction of p19INK4D by IL-10 contributes to inhibition of macrophage proliferation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Biochemical characterization of p16INK4- and p18-containing complexes in human cell lines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Targeted disruption of the mouse Stat3 gene leads to early embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Suppression of cell transformation by the cyclin-dependent kinase inhibitor p57KIP2 requires binding to proliferating cell nuclear antigen

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Postnatal neuronal proliferation in mice lacking Ink4d and Kip1 inhibitors of cyclin-dependent kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

Crystal structure of the complex of the cyclin D-dependent kinase Cdk6 bound to the cell-cycle inhibitor p19INK4d

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Interaction with cyclin-dependent kinases and PCNA modulates proteasome-dependent degradation of p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

A cyclin-dependent kinase inhibitor, Dacapo, is necessary for timely exit from the cell cycle during Drosophila embryogenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

WAF1, a potential mediator of p53 tumor suppression

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cyclin D does not provide essential Cdk4-independent functions in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27(Kip1)-deficient mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cyclins and cancer. II: Cyclin D and CDK inhibitors come of age

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Enhanced growth of mice lacking the cyclin-dependent kinase inhibitor function of p27(Kip1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Tumour-derived p16 alleles encoding proteins defective in cell-cycle inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Mouse development and cell proliferation in the absence of D-cyclins.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Loss of p16Ink4a confers susceptibility to metastatic melanoma in mice

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Dacapo, a cyclin-dependent kinase inhibitor, stops cell proliferation during Drosophila development.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cyclin E2: a novel CDK2 partner in the late G1 and S phases of the mammalian cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Isolation of three novel human cyclins by rescue of G1 cyclin (cln) function in yeast

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Retinoblastoma-protein-dependent cell-cycle inhibition by the tumour suppressor p16

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cell-cycle inhibition by independent CDK and PCNA binding domains in p21Cip1

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Mammalian cells cycle without the D-type cyclin-dependent kinases Cdk4 and Cdk6

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Pituitary Hypoplasia and Lactotroph Dysfunction in Mice Deficient for Cyclin-Dependent Kinase-4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

The C-terminal region of p21SDI1/WAF1/CIP1 is involved in proliferating cell nuclear antigen binding but does not appear to be required for growth inhibition

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Mice lacking p27(Kip1) display increased body size, multiple organ hyperplasia, retinal dysplasia, and pituitary tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cell cycle control: a complex issue

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Role of the ubiquitin-proteasome pathway in regulating abundance of the cyclin-dependent kinase inhibitor p27

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Chronic Myeloid Leukemia with Increased Granulocyte Progenitors in Mice Lacking JunB Expression in the Myeloid Lineage

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

p27Kip1, a cyclin-Cdk inhibitor, links transforming growth factor-beta and contact inhibition to cell cycle arrest

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

The INK4 family of cell cycle inhibitors in cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Crystal structure of the p27Kip1 cyclin-dependent-kinase inhibitor bound to the cyclin A-Cdk2 complex

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Structural basis for inhibition of the cyclin-dependent kinase Cdk6 by the tumour suppressor p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Loss of p16Ink4a with retention of p19Arf predisposes mice to tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

1 reference

7 January 2021

Living with or without cyclins and cyclin-dependent kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Activation of cyclin D1-kinase in murine fibroblasts lacking both p21(Cip1) and p27(Kip1).

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

The p21 inhibitor of cyclin-dependent kinases controls DNA replication by interaction with PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

The retinoblastoma protein and cell cycle control

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

p21 is a universal inhibitor of cyclin kinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

D type cyclins associate with multiple protein kinases and the DNA replication and repair factor PCNA

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Subunit rearrangement of the cyclin-dependent kinases is associated with cellular transformation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Cyclin E2, a novel human G1 cyclin and activating partner of CDK2 and CDK3, is induced by viral oncoproteins

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1208611

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1208611

1 reference

12 August 2017

1 reference

PubMed ID

15838515