Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis. (Q36102304)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422450%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

title

Ouabain-induced perturbations in intracellular ionic homeostasis regulate death receptor-mediated apoptosis (English)

1 reference

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1 February 2020

1

1 reference

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1 February 2020

Rodrigo Franco

series ordinal

2

1 reference

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1 February 2020

John A Cidlowski

series ordinal

4

1 reference

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1 February 2020

3

Carl D Bortner

1 reference

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1 February 2020

publication date

1 July 2010

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1 February 2020

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1 February 2020

volume

15

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1 February 2020

issue

7

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1 February 2020

page(s)

834-849

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Death of ouabain-treated renal epithelial cells: evidence for p38 MAPK-mediated Na (i) (+) /K (i) (+) -independent signaling

1 February 2020

cites work

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Glutathione depletion and disruption of intracellular ionic homeostasis regulate lymphoid cell apoptosis

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2 October 2017

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2 October 2017

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Loss of caspase-9 provides genetic evidence for the type I/II concept of CD95-mediated apoptosis

2 October 2017

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The inotropic effect of cardioactive glycosides in ventricular myocytes requires Na+-Ca2+ exchanger function

2 October 2017

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The death of cardiotonic steroid-treated cells: evidence of Na+i,K+i-independent H+i-sensitive signalling

2 October 2017

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On the mechanism of ionic regulation of apoptosis: would the Na+/K+-ATPase please stand up?

2 October 2017

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Potential roles of electrogenic ion transport and plasma membrane depolarization in apoptosis.

2 October 2017

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Volume-sensitive chloride channels involved in apoptotic volume decrease and cell death.

2 October 2017

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Apoptosis: a basic biological phenomenon with wide-ranging implications in human disease

2 October 2017

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Na/K-ATPase tethers phospholipase C and IP3 receptor into a calcium-regulatory complex

2 October 2017

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Programmed cell death via mitochondria: different modes of dying.

2 October 2017

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Ouabain induces apoptotic cell death in type I spiral ganglion neurons, but not type II neurons

2 October 2017

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Changes in intracellular sodium, chlorine, and potassium concentrations in staurosporine-induced apoptosis.

2 October 2017

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Death receptor signals to mitochondria

2 October 2017

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Cardiotonic steroids differentially affect intracellular Na+ and [Na+]i/[K+]i-independent signaling in C7-MDCK cells

2 October 2017

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Apoptosis in serum-deprived vascular smooth muscle cells: evidence for cell volume-independent mechanism.

2 October 2017

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Calcium and apoptosis: facts and hypotheses

2 October 2017

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The CD95 type I/type II model

2 October 2017

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Na+, K+-ATPase: the new face of an old player in pathogenesis and apoptotic/hybrid cell death

2 October 2017

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Cell signaling microdomain with Na,K-ATPase and inositol 1,4,5-trisphosphate receptor generates calcium oscillations

2 October 2017

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2 October 2017

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Stimulation of Kv1.3 potassium channels by death receptors during apoptosis in Jurkat T lymphocytes

2 October 2017

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The Na/K pump, Cl ion, and osmotic stabilization of cells

2 October 2017

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Inhibition of Na+,K+-ATPase by ouabain triggers epithelial cell death independently of inversion of the [Na+]i/[K+]i ratio

2 October 2017

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Apoptotic volume decrease and the incredible shrinking cell

2 October 2017

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Na+ pump alpha 2-subunit expression modulates Ca2+ signaling

2 October 2017

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Ouabain application to the round window of the gerbil cochlea: a model of auditory neuropathy and apoptosis

2 October 2017

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Protein kinase C-alpha and ERK1/2 mediate mitochondrial dysfunction, decreases in active Na+ transport, and cisplatin-induced apoptosis in renal cells

2 October 2017

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Mitochondria, the killer organelles and their weapons

2 October 2017

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Distinct intracellular signaling in tumor necrosis factor-related apoptosis-inducing ligand- and CD95 ligand-mediated apoptosis

2 October 2017

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Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

2 October 2017

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Analysis of laser scattering pattern as an early measure of apoptosis

2 October 2017

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Ouabain, a steroid hormone that signals with slow calcium oscillations.

2 October 2017

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Inhibition of Na,K-ATPase activates PI3 kinase and inhibits apoptosis in LLC-PK1 cells

2 October 2017

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Fas aggregation does not correlate with Fas-mediated apoptosis

2 October 2017

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Distinct PKC isozymes regulate bufalin-induced differentiation and apoptosis in human monocytic cells

2 October 2017

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Plasma membrane depolarization without repolarization is an early molecular event in anti-Fas-induced apoptosis.

2 October 2017

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The biochemistry of apoptosis

2 October 2017

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Mechanisms of sodium pump regulation

2 October 2017

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2 October 2017

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Cadmium-mediated oxidative stress in kidney proximal tubule cells induces degradation of Na+/K(+)-ATPase through proteasomal and endo-/lysosomal proteolytic pathways

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Na+/Ca2+ exchange-mediated calcium entry in human lymphocytes

2 October 2017

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Fas antigen-mediated DNA fragmentation and apoptotic morphologic changes are regulated by elevated cytosolic Ca2+ level.

2 October 2017

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A dominant negative Fas-associated death domain protein mutant inhibits proliferation and leads to impaired calcium mobilization in both T-cells and fibroblasts

2 October 2017

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Short-term block of Na+/K+-ATPase in neuro-glial cell cultures of cerebellum induces glutamate dependent damage of granule cells

2 July 2018

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Ouabain induces apoptosis on PHA-activated lymphocytes

2 July 2018

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Association of BCL-2 with membrane hyperpolarization and radioresistance

2 July 2018

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Cell volume changes upon sodium pump inhibition in Helix aspersa neurones

2 July 2018

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Signal pathways in ouabain-induced proliferation of leukemia cells

2 July 2018

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Altered Na+/Ca2+-exchanger activity due to downregulation of Na+/K+-ATPase alpha2-isoform in heart failure

23 September 2018

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Clearance of store-released Ca2+ by the Na+-Ca2+ exchanger is diminished in aortic smooth muscle from Na+-K+-ATPase alpha 2-isoform gene-ablated mice

23 September 2018

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The rapid decline of MTT reduction is not a marker of death signaling in ouabain-treated cells

23 September 2018

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Ionic mechanism of ouabain-induced swelling of leech Retzius neurons

23 September 2018

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Low-dose ouabain protects against excitotoxic apoptosis and up-regulates nuclear Bcl-2 in vivo

23 September 2018

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Cell shrinkage as a signal to apoptosis in NIH 3T3 fibroblasts

23 September 2018

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Novel regulation of Na, K-ATPase by Src tyrosine kinases in cortical neurons

23 September 2018

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Ouabain induces an increase of retinal ganglion cell survival in vitro: the involvement of protein kinase C.

23 September 2018

1 reference

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Antiapoptotic effect of ouabain on human umbilical vein endothelial cells

23 September 2018

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Camptothecin-induced imbalance in intracellular cation homeostasis regulates programmed cell death in unicellular hemoflagellate Leishmania donovani

23 September 2018

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Impaired Na+,K+-ATPase activity as a mechanism of reactive nitrogen species-induced cytotoxicity in guinea pig liver exposed to lipopolysaccharides

23 September 2018

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Na+/K+ pump and endothelial cell survival: [Na+]i/[K+]i-independent necrosis triggered by ouabain, and protection against apoptosis mediated by elevation of [Na+]i

23 September 2018

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Investigation of ouabain-induced anticancer effect in human androgen-independent prostate cancer PC-3 cells.

23 September 2018

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Uncoupling cell shrinkage from apoptosis reveals that Na+ influx is required for volume loss during programmed cell death

23 September 2018

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[3H]-thymidine labelling of DNA triggers apoptosis potentiated by E1A-adenoviral protein

23 September 2018

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Ca2+Mobilization Induced by Ouabain in Thymocytes Involves Intracellular and Extracellular Ca2+Pools

23 September 2018

1 reference

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Apoptotic insults impair Na+, K+-ATPase activity as a mechanism of neuronal death mediated by concurrent ATP deficiency and oxidant stress

23 September 2018

1 reference

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Block of Na+,K+-ATPase and induction of hybrid death by 4-aminopyridine in cultured cortical neurons

23 September 2018

1 reference

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Mitochondrial membrane permeabilization and superoxide production during apoptosis. A single-cell analysis

23 September 2018

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Outer mitochondrial membrane permeabilization during apoptosis triggers caspase-independent mitochondrial and caspase-dependent plasma membrane potential depolarization: a single-cell analysis

23 September 2018

1 reference

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Slight impairment of Na+,K+-ATPase synergistically aggravates ceramide- and beta-amyloid-induced apoptosis in cortical neurons

23 September 2018

1 reference

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Evaluation of neuroprotection by lithium and valproic acid against ouabain-induced cell damage

23 September 2018

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Ionic mechanism of ouabain-induced concurrent apoptosis and necrosis in individual cultured cortical neurons.

23 September 2018

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Glucocorticoid-induced plasma membrane depolarization during thymocyte apoptosis: association with cell shrinkage and degradation of the Na(+)/K(+)-adenosine triphosphatase

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

Glutamine deprivation-mediated cell shrinkage induces ligand-independent CD95 receptor signaling and apoptosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

Dual effects of ouabain on the regulation of proliferation and apoptosis in human prostatic smooth muscle cells

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

A role for potassium in TNF-induced apoptosis and gene-induction in human and rodent tumour cell lines

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

Influence of Bcl-2 overexpression on Na+/K(+)-ATPase pump activity: correlation with radiation-induced programmed cell death

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

Role of cell membrane Na,K-ATPase for survival of human lymphocytes in vitro

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3399447

Cardiac glycosides stimulate Ca2+ increases and apoptosis in androgen-independent, metastatic human prostate adenocarcinoma cells

23 September 2018

1 reference

12 December 2020

Ouabain interaction with cardiac Na+/K+-ATPase initiates signal cascades independent of changes in intracellular Na+ and Ca2+ concentrations

1 reference

12 December 2020

A selective requirement for elevated calcium in DNA degradation, but not early events in anti-Fas-induced apoptosis

1 reference

12 December 2020

Inhibition of Na+/K(+)-ATPase may be one mechanism contributing to potassium efflux and cell shrinkage in CD95-induced apoptosis

1 reference

12 December 2020

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

1 reference

12 December 2020

Proteome Analysis and Functional Expression Identify Mortalin as an Antiapoptotic Gene Induced by Elevation of [Na + ] i /[K + ] i Ratio in Cultured Vascular Smooth Muscle Cells

1 reference

12 December 2020

Modulation of Na+/K+ pump in intact erythrocytes by cardioglycosides, steroid hormones and ouabain-like compounds

1 reference

12 December 2020

Inversion of the intracellular Na+/K+ ratio blocks apoptosis in vascular smooth muscle at a site upstream of caspase-3

1 reference

12 December 2020

Induction of apoptosis by bufalin in human tumor cells is associated with a change of intracellular concentration of Na+ ions

1 reference

12 December 2020

The Na+-Ca2+ exchanger is essential for the action of cardiac glycosides

1 reference

12 December 2020

Transmembrane ion movements elicited by sodium pump inhibition in Helix aspersa neurons

1 reference

12 December 2020

Role of Apoptosis in Growth and Differentiation of Proximal Tubule Cells in Primary Cultures

1 reference

12 December 2020

Absence of volume regulatory mechanisms contributes to the rapid activation of apoptosis in thymocytes

1 reference

12 December 2020

Intracellular K+ suppresses the activation of apoptosis in lymphocytes

1 reference

12 December 2020

A primary role for K+ and Na+ efflux in the activation of apoptosis

1 reference

12 December 2020

Ouabain exacerbates activation-induced cell death in human peripheral blood lymphocytes

1 reference

12 December 2020

Proteomic analysis of vascular smooth muscle cells treated with ouabain

1 reference

12 December 2020

Impairment of Na(+),K(+)-ATPase in CD95(APO-1)-induced human T-cell leukemia cell apoptosis mediated by glutathione depletion and generation of hydrogen peroxide

1 reference

12 December 2020

Inhibition of Na+,K+-ATPase activity in cultured rat cerebellar granule cells prevents the onset of apoptosis induced by low potassium

1 reference

12 December 2020

Inversion of the intracellular Na(+)/K(+) ratio blocks apoptosis in vascular smooth muscle cells by induction of RNA synthesis

1 reference

12 December 2020

10.1007/S10495-010-0494-8

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422450%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20422450%20AND%20SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

20422450

1 reference