The CD95 type I/type II model (Q35561587)

8 August 2017

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title

The CD95 type I/type II model (English)

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8 August 2017

Marcus E Peter

3

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author name string

Bryan C Barnhart

series ordinal

1

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PubMed ID

14563117

8 August 2017

Elizabeth C Alappat

series ordinal

2

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8 August 2017

1 June 2003

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8 August 2017

Seminars in Immunology

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8 August 2017

15

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8 August 2017

3

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8 August 2017

185-193

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The biochemistry of apoptosis

8 August 2017

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Apoptosome: the seven-spoked death machine

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Mitochondria and apoptosis

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

1 reference

7 January 2021

FLICE is activated by association with the CD95 death-inducing signaling complex (DISC).

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Two CD95 (APO-1/Fas) signaling pathways

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Cleavage of BID by caspase 8 mediates the mitochondrial damage in the Fas pathway of apoptosis

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bid, a Bcl2 interacting protein, mediates cytochrome c release from mitochondria in response to activation of cell surface death receptors

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Activation of Fas by FasL induces apoptosis by a mechanism that cannot be blocked by Bcl-2 or Bcl-x(L)

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

TRAIL-R2: a novel apoptosis-mediating receptor for TRAIL.

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Differences between CD95 type I and II cells detected with the CD95 ligand

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-2 does not inhibit cell death induced by the physiological Fas ligand: implications for the existence of type I and type II cells

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-2 and Fas/APO-1 regulate distinct pathways to lymphocyte apoptosis

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl–2 protects from lethal hepatic apoptosis induced by an ant–Fas antibody in mice

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

A bcl-2 transgene expressed in hepatocytes protects mice from fulminant liver destruction but not from rapid death induced by anti-Fas antibody injection

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bax-deficient mice with lymphoid hyperplasia and male germ cell death

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Apaf1 is required for mitochondrial pathways of apoptosis and brain development

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Differential requirement for caspase 9 in apoptotic pathways in vivo.

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Reduced apoptosis and cytochrome c-mediated caspase activation in mice lacking caspase 9

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Molecular characterization of mitochondrial apoptosis-inducing factor

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Endonuclease G is an apoptotic DNase when released from mitochondria

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Molecular ordering of the initial signaling events of CD95.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-xL acts downstream of caspase-8 activation by the CD95 death-inducing signaling complex.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-xL functions downstream of caspase-8 to inhibit Fas- and tumor necrosis factor receptor 1-induced apoptosis of MCF7 breast carcinoma cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Inactivation of caspase-8 on mitochondria of Bcl-xL-expressing MCF7-Fas cells: role for the bifunctional apoptosis regulator protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Phosphorylation by protein kinase CK2: a signaling switch for the caspase-inhibiting protein ARC

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Downregulation of Fas ligand by shedding

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

CD95 (APO-1/Fas) linkage to the actin cytoskeleton through ezrin in human T lymphocytes: a novel regulatory mechanism of the CD95 apoptotic pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Actin cytoskeleton is required for early apoptosis signaling induced by anti-Fas antibody but not Fas ligand in murine B lymphoma A20 cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Apoptosis induced by disruption of the actin cytoskeleton is mediated via activation of CD95 (Fas/APO-1).

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Phosphatidylinositol 3'-kinase blocks CD95 aggregation and caspase-8 cleavage at the death-inducing signaling complex by modulating lateral diffusion of CD95

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

IAPs block apoptotic events induced by caspase-8 and cytochrome c by direct inhibition of distinct caspases

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-2 and Bcl-xL inhibit CD95-mediated apoptosis by preventing mitochondrial release of Smac/DIABLO and subsequent inactivation of X-linked inhibitor-of-apoptosis protein

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

XIAP inhibition of caspase-3 preserves its association with the Apaf-1 apoptosome and prevents CD95- and Bax-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Molecular determinants of the caspase-promoting activity of Smac/DIABLO and its role in the death receptor pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Generation and characterization of Smac/DIABLO-deficient mice.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Activation of protein kinase C attenuates early signals in Fas-mediated apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Inhibition of the protein kinase C pathway promotes anti-CD95-induced apoptosis in Jurkat T cells

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Differential modulation of apoptosis sensitivity in CD95 type I and type II cells.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

A functional role for mitochondrial protein kinase Calpha in Bcl2 phosphorylation and suppression of apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

p90(RSK) blocks bad-mediated cell death via a protein kinase C-dependent pathway

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Protein kinase C-theta mediates a selective T cell survival signal via phosphorylation of BAD

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

The protective effect of phorbol esters on Fas-mediated apoptosis in T cells. Transcriptional and postranscriptional regulation.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Phorbol 12-myristate 13-acetate inhibits death receptor-mediated apoptosis in Jurkat cells by disrupting recruitment of Fas-associated polypeptide with death domain

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Protein kinase C regulates FADD recruitment and death-inducing signaling complex formation in Fas/CD95-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Expression of the functional soluble form of human fas ligand in activated lymphocytes.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Autocrine T-cell suicide mediated by APO-1/(Fas/CD95)

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Fas ligand in human serum

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Soluble Fas ligand in the joints of patients with rheumatoid arthritis and osteoarthritis

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Conversion of membrane-bound Fas(CD95) ligand to its soluble form is associated with downregulation of its proapoptotic activity and loss of liver toxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Extracellular matrix interacts with soluble CD95L: retention and enhancement of cytotoxicity

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

The metalloproteinase matrilysin proteolytically generates active soluble Fas ligand and potentiates epithelial cell apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Apo2L/TRAIL-dependent recruitment of endogenous FADD and caspase-8 to death receptors 4 and 5.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

FADD/MORT1 and caspase-8 are recruited to TRAIL receptors 1 and 2 and are essential for apoptosis mediated by TRAIL receptor 2

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

TRAIL receptor-2 signals apoptosis through FADD and caspase-8

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https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

TRAIL receptor and CD95 signal to mitochondria via FADD, caspase-8/10, Bid, and Bax but differentially regulate events downstream from truncated Bid

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Inhibition of TRAIL-induced apoptosis by Bcl-2 overexpression.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

TRAIL (APO-2L) induces apoptosis in human prostate cancer cells that is inhibitable by Bcl-2.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Bcl-2 oncoprotein protects the human prostatic carcinoma cell line PC3 from TRAIL-mediated apoptosis.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Failure of Bcl-2 to block cytochrome c redistribution during TRAIL-induced apoptosis

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Defining characteristics of Types I and II apoptotic cells in response to TRAIL.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Intracellular mechanisms of TRAIL: apoptosis through mitochondrial-dependent and -independent pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Tumor-cell resistance to death receptor--induced apoptosis through mutational inactivation of the proapoptotic Bcl-2 homolog Bax.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Tumor necrosis factor receptor and Fas signaling mechanisms.

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

Dual signaling of the Fas receptor: initiation of both apoptotic and necrotic cell death pathways

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptor

1 reference

https://api.crossref.org/works/10.1016%2FS1044-5323%2803%2900031-9

7 January 2021

10.1016/S1044-5323(03)00031-9

Identifiers

DOI

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8 August 2017

1 reference

PubMed ID

14563117