Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option (Q36110001)

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English	Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option	scientific article

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scholarly article

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Europe PubMed Central

PMC publication ID

12 August 2017

Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option (English)

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

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corrigendum / erratum

Erratum to: Inhibition of BRCT(BRCA1)-phosphoprotein interaction enhances the cytotoxic effect of olaparib in breast cancer cells: a proof of concept study for synthetic lethal therapeutic option

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Amarnath Natarajan

4

object named as

Amarnath Natarajan

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Europe PubMed Central

PMC publication ID

12 August 2017

author name string

Ziyan Yuan Pessetto

1

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

Ying Yan

2

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Europe PubMed Central

PMC publication ID

12 August 2017

Tadayoshi Bessho

3

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Europe PubMed Central

PMC publication ID

12 August 2017

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publication date

6 May 2012

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Europe PubMed Central

PMC publication ID

12 August 2017

Breast Cancer Research and Treatment

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Europe PubMed Central

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12 August 2017

134

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Europe PubMed Central

PMC publication ID

12 August 2017

2

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Europe PubMed Central

PMC publication ID

12 August 2017

511-517

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Europe PubMed Central

PMC publication ID

12 August 2017

Exploiting the P-1 pocket of BRCT domains toward a structure guided inhibitor design

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

BRCA mutations in the management of breast cancer: the state of the art

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

A review of PARP inhibitors: from bench to bedside

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Comparison of the structures and peptide binding specificities of the BRCT domains of MDC1 and BRCA1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Structural characterization of BRCT-tetrapeptide binding interactions.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Inhibition of poly(ADP-ribose) polymerase in tumors from BRCA mutation carriers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Targeting the DNA repair defect in BRCA mutant cells as a therapeutic strategy

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Human Fanconi anemia monoubiquitination pathway promotes homologous DNA repair

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

The BRCT Domain Is a Phospho-Protein Binding Domain

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Ku DNA end-binding protein modulates homologous repair of double-strand breaks in mammalian cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Chromosomal double-strand breaks introduced in mammalian cells by expression of I-Sce I endonuclease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 October 2017

Structure-activity relationship studies to probe the phosphoprotein binding site on the carboxy terminal domains of the breast cancer susceptibility gene 1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3402595

2 July 2018

High-throughput fluorescence polarization assay to identify small molecule inhibitors of BRCT domains of breast cancer gene 1.

1 reference

https://api.crossref.org/works/10.1007%2FS10549-012-2079-4

21 January 2018

Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design

1 reference

https://pubmed.ncbi.nlm.nih.gov/22562176

12 December 2020

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10.1007/S10549-012-2079-4

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

12 August 2017

ResearchGate publication ID

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