Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction (Q33312344)

25 July 2017

title

Dual-fluorophore quantitative high-throughput screen for inhibitors of BRCT-phosphoprotein interaction (English)

1 reference

high-throughput screening

25 July 2017

main subject

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8

Amarnath Natarajan

1 reference

25 July 2017

Adam Yasgar

2

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Ajit Jadhav

object named as

Ajit Jadhav

3

0 references

Anton Simeonov

1

object named as

Anton Simeonov

1 reference

25 July 2017

7

Christopher P Austin

1 reference

25 July 2017

G L Lokesh

4

1 reference

25 July 2017

Carleen Klumpp

5

1 reference

25 July 2017

Sam Michael

6

1 reference

25 July 2017

James Inglese

9

1 reference

25 July 2017

language of work or name

English

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publication date

5 December 2007

1 reference

25 July 2017

published in

Analytical Biochemistry

1 reference

25 July 2017

volume

375

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25 July 2017

issue

1

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25 July 2017

page(s)

60-70

1 reference

Quantitative high-throughput screen identifies inhibitors of the Schistosoma mansoni redox cascade

25 July 2017

cites work

1 reference

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CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

CCDC98 targets BRCA1 to DNA damage sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

High-throughput screening assays for the identification of chemical probes

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Ubiquitin-binding protein RAP80 mediates BRCA1-dependent DNA damage response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

RAP80 targets BRCA1 to specific ubiquitin structures at DNA damage sites

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Quantitative high-throughput screening: a titration-based approach that efficiently identifies biological activities in large chemical libraries

21 June 2018

1 reference

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Pharmacology. Hitting the hot spots of cell signaling cascades

21 June 2018

1 reference

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High-throughput assays for promiscuous inhibitors.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Nanoliter dispensing for uHTS using pin tools

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Piezo- and solenoid valve-based liquid dispensing for miniaturized assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

NIH Molecular Libraries Initiative

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

DNA damage-induced cell cycle checkpoint control requires CtIP, a phosphorylation-dependent binding partner of BRCA1 C-terminal domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structural basis of BACH1 phosphopeptide recognition by BRCA1 tandem BRCT domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structural basis of phosphopeptide recognition by the BRCT domain of BRCA1.

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structure and mechanism of BRCA1 BRCT domain recognition of phosphorylated BACH1 with implications for cancer

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structure of the BRCT Repeats of BRCA1 Bound to a BACH1 Phosphopeptide

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Small-molecule inhibitors of protein-protein interactions: progressing towards the dream

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Phosphopeptide Binding Specificities of BRCA1 COOH-terminal (BRCT) Domains

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

The BRCT Domain Is a Phospho-Protein Binding Domain

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

BRCT Repeats As Phosphopeptide-Binding Modules Involved in Protein Targeting

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Binding of small molecules to an adaptive protein-protein interface

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

BACH1, a novel helicase-like protein, interacts directly with BRCA1 and contributes to its DNA repair function

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Simultaneous determination of doxorubicin, daunorubicin, and idarubicin by capillary electrophoresis with laser-induced fluorescence detection

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

A Simple Statistical Parameter for Use in Evaluation and Validation of High Throughput Screening Assays

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

The C-terminal (BRCT) domains of BRCA1 interact in vivo with CtIP, a protein implicated in the CtBP pathway of transcriptional repression

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Anatomy of hot spots in protein interfaces

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

A high-throughput screen for aggregation-based inhibition in a large compound library

21 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

High-throughput fluorescence polarization assay to identify small molecule inhibitors of BRCT domains of breast cancer gene 1.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structural basis for cell cycle checkpoint control by the BRCA1-CtIP complex.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Structure of the BRCT repeats of BRCA1 bound to a BACH1 phosphopeptide: implications for signaling

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

Studies on repository compound stability in DMSO under various conditions

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

The effect of room-temperature storage on the stability of compounds in DMSO.

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3389998

The minimum significant ratio: a statistical parameter to characterize the reproducibility of potency estimates from concentration-response assays and estimation by replicate-experiment studies

31 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18158907

12 December 2020

inferred from PubMed ID database lookup

A novel inhibitor of Mycobacterium tuberculosis pantothenate synthetase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18158907

12 December 2020

inferred from PubMed ID database lookup

Thermodynamics of phosphopeptide tethering to BRCT: the structural minima for inhibitor design

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18158907

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.AB.2007.11.039

1 reference

release_gysrrzr23vcyhlqqvetyn4z6b4

25 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gysrrzr23vcyhlqqvetyn4z6b4

24 November 2022

mapped directly with Wikidata item

PMC publication ID

3389998

1 reference

25 July 2017

1 reference