The versatile roles of antibodies in Borrelia infections (Q36111888)

12 August 2017

1 reference

title

The versatile roles of antibodies in Borrelia infections (English)

1 reference

12 August 2017

1 reference

Sean E Connolly

1

1 reference

12 August 2017

Jorge L Benach

series ordinal

2

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 May 2005

1 reference

Nature Reviews Microbiology

12 August 2017

1 reference

12 August 2017

3

1 reference

12 August 2017

5

1 reference

12 August 2017

411-420

1 reference

https://scigraph.springernature.com/pub.10.1038/nrmicro1149

12 August 2017

0 references

cites work

Lyme disease-a tick-borne spirochetosis?

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Experimental Relapsing Fever Initiated by Borrelia hermsi: II. Sequential Appearance of Major Serotypes in the Rat

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Antigenic variation of a relapsing fever Borrelia species

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Antigenic variation of Borrelia hermsii

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Variable major proteins of Borrelia hermsii. Epitope mapping and partial sequence analysis of CNBr peptides

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The variable antigens Vmp7 and Vmp21 of the relapsing fever bacterium Borrelia hermsii are structurally analogous to the VSG proteins of the African trypanosome

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Molecular analysis of linear plasmid-encoded major surface proteins, OspA and OspB, of the Lyme disease spirochaete Borrelia burgdorferi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Genomic sequence of a Lyme disease spirochaete, Borrelia burgdorferi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Genetic transformation of the Lyme disease agent Borrelia burgdorferi with coumarin-resistant gyrB

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Efficient targeted mutagenesis in Borrelia burgdorferi

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The burgeoning molecular genetics of the Lyme disease spirochaete

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Complement. First of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Complement. Second of two parts

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Complement evasion by Borrelia burgdorferi: serum-resistant strains promote C3b inactivation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Complement inhibitor factor H binding to Lyme disease spirochetes is mediated by inducible expression of multiple plasmid-encoded outer surface protein E paralogs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Differential binding of host complement inhibitor factor H by Borrelia burgdorferi Erp surface proteins: a possible mechanism underlying the expansive host range of Lyme disease spirochetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Immune evasion of Borrelia burgdorferi: mapping of a complement-inhibitor factor H-binding site of BbCRASP-3, a novel member of the Erp protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The factor H protein family

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Human complement component C3: cDNA coding sequence and derived primary structure

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Serum-resistant strains of Borrelia burgdorferi evade complement-mediated killing by expressing a CD59-like complement inhibitory molecule

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Identification and characterization of a linear-plasmid-encoded factor H-binding protein (FhbA) of the relapsing fever spirochete Borrelia hermsii.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Fc- and non-Fc-mediated phagocytosis of Borrelia burgdorferi by macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Evidence of involvement of the mannose receptor in adhesion of Borrelia burgdorferi to monocyte/macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Borrelia burgdorferi are susceptible to killing by a variety of human polymorphonuclear leukocyte components

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Therapeutic passive vaccination against chronic Lyme disease in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Monoclonal antibodies specific for the outer surface protein A (OspA) of Borrelia burgdorferi prevent Lyme borreliosis in severe combined immunodeficiency (scid) mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Induction of an outer surface protein on Borrelia burgdorferi during tick feeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Protection against antigenically variable Borrelia burgdorferi conferred by recombinant vaccines

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Borrelia burgdorferi OspA is an arthropod-specific transmission-blocking Lyme disease vaccine

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The outer surface protein A (OspA) of Borrelia burgdorferi: a vaccine candidate and bioactive mediator

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Vaccination against Lyme disease with recombinant Borrelia burgdorferi outer-surface lipoprotein A with adjuvant. Lyme Disease Vaccine Study Group

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

A vaccine consisting of recombinant Borrelia burgdorferi outer-surface protein A to prevent Lyme disease. Recombinant Outer-Surface Protein A Lyme Disease Vaccine Study Consortium

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Identification of LFA-1 as a candidate autoantigen in treatment-resistant Lyme arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Cellular immune reactivity to recombinant OspA and flagellin from Borrelia burgdorferi in patients with Lyme borreliosis. Complexity of humoral and cellular immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The T helper cell response in Lyme arthritis: differential recognition of Borrelia burgdorferi outer surface protein A in patients with treatment-resistant or treatment-responsive Lyme arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Hyporesponsiveness to vaccination with Borrelia burgdorferi OspA in humans and in TLR1- and TLR2-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Cutting edge: T cell-mediated pathology in murine Lyme borreliosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Cutting edge: the spirochetemia of murine relapsing fever is cleared by complement-independent bactericidal antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Generation of a complement-independent bactericidal IgM against a relapsing fever Borrelia

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

In vitro and in vivo neutralization of the relapsing fever agent Borrelia hermsii with serotype-specific immunoglobulin M antibodies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Borrelia burgdorferi adherence and injury to undifferentiated and differentiated neural cells in vitro.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

An immune evasion mechanism for spirochetal persistence in Lyme borreliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

A mouse model of Borrelia meningitis after intradermal injection.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The resolution of relapsing fever borreliosis requires IgM and is concurrent with expansion of B1b lymphocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Variability of a bacterial surface protein and disease expression in a possible mouse model of systemic Lyme borreliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Targeted gene disruption reveals a role for natural secretory IgM in the maturation of the primary immune response

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Marginal zone and B1 B cells unite in the early response against T-independent blood-borne particulate antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

B1b lymphocytes confer T cell-independent long-lasting immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Erythrocyte-aggregating relapsing fever spirochete Borrelia crocidurae induces formation of microemboli

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The relapsing fever spirochaete, Borrelia crocidurae, activates human endothelial cells and promotes the transendothelial migration of neutrophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Fc alpha/mu receptor mediates endocytosis of IgM-coated microbes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Role of natural and immune IgM antibodies in immune responses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

B cells and antibody play critical roles in the immediate defense of disseminated infection by West Nile encephalitis virus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

A Critical Role for Induced IgM in the Protection against West Nile Virus Infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

B-1 and B-2 cell-derived immunoglobulin M antibodies are nonredundant components of the protective response to influenza virus infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Natural antibody affects survival of the spirochete Borrelia burgdorferi within feeding ticks

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

21 January 2018

Marginal-zone B cells

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Whole-genome DNA array analysis of the response of Borrelia burgdorferi to a bactericidal monoclonal antibody

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The relapsing fever spirochete Borrelia hermsii contains multiple, antigen-encoding circular plasmids that are homologous to the cp32 plasmids of Lyme disease spirochetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Antibodies have the intrinsic capacity to destroy antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Antibody-based therapies for emerging infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Passive antibody administration (immediate immunity) as a specific defense against biological weapons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Return to the Past: The Case for Antibody-Based Therapies in Infectious Diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Immunotoxins: redirecting nature's poisons

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Redesigning nature's poisons to create anti-tumor reagents

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Ionizing radiation delivered by specific antibody is therapeutic against a fungal infection

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Passive antibody therapy for infectious diseases

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Characterization of antigenic determinants of Borrelia burgdorferi shared by other bacteria

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Evidence for the production of trioxygen species during antibody-catalyzed chemical modification of antigens

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Spirochetes Isolated from the Blood of Two Patients with Lyme Disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

21 January 2018

Lyme neuroborreliosis

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Borreliacidal antibody production against outer surface protein C of Borrelia burgdorferi

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

The complement regulator factor H binds to the surface protein OspE of Borrelia burgdorferi

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Interactions of phagocytes with the Lyme disease spirochete: role of the Fc receptor

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Cellular immune findings in Lyme disease Correlation with serum IgM and disease activity

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Sera from patients with chronic Lyme disease protect mice from Lyme borreliosis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Protection of mice against the Lyme disease agent by immunizing with recombinant OspA

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Mode of inoculation of the Lyme disease agent Borrelia burgdorferi influences infection and immune responses in inbred strains of mice

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Distinct patterns of protective antibodies are generated against Borrelia burgdorferi in mice experimentally inoculated with high and low doses of antigen

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Immune sera to individual Borrelia burgdorferi isolates or recombinant OspA thereof protect SCID mice against infection with homologous strains but only partially or not at all against those of different OspA/OspB genotype

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Immunization with a polyvalent OspA vaccine protects mice against Ixodes ricinus tick bites infected by Borrelia burgdorferi ss, Borrelia garinii and Borrelia afzelii

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Protection against Borrelia burgdorferi infection in SCID mice is conferred by presensitized spleen cells and partially by B but not T cells alone

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

A bactericidal monoclonal antibody elicits a change in its antigen, OspB of Borrelia burgdorferi, that can be detected by limited proteolysis

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Control of early viral and bacterial distribution and disease by natural antibodies

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

Immunogenic integral membrane proteins of Borrelia burgdorferi are lipoproteins

31 March 2020

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Role of immunoglobulin G in killing of Borrelia burgdorferi by the classical complement pathway

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Facilitation of complement-dependent killing of the Lyme disease spirochete, Borrelia burgdorferi, by specific immunoglobulin G Fab antibody fragments.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Borreliacidal activity of sera from hamsters infected with the Lyme disease spirochete

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Passive immunization of hamsters against experimental infection with the Lyme disease spirochete

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Passive immunizing activity of sera from mice infected with Borrelia burgdorferi

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Dominant recognition of a Borrelia burgdorferi outer surface protein A peptide by T helper cells in patients with treatment-resistant Lyme arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

In vivo evidence that an intact lytic complement pathway is not essential for successful removal of circulating Borrelia turicatae from mouse blood

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Borrelia burgdorferi outer surface lipoproteins OspA and OspB possess B-cell mitogenic and cytokine-stimulatory properties

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Evidence for B-lymphocyte mitogen activity in Borrelia burgdorferi-infected mice

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Normal human B lymphocytes and mononuclear cells respond to the mitogenic and cytokine-stimulatory activities of Borrelia burgdorferi and its lipoprotein OspA.

1 reference

https://api.crossref.org/works/10.1038%2FNRMICRO1149

7 January 2021

Identifiers

DOI

10.1038/NRMICRO1149

1 reference

Dimensions Publication ID

12 August 2017

0 references

1 reference