Obesity and metabolic disease: is adipose tissue the culprit? (Q36118722)

12 August 2017

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title

Obesity and metabolic disease: is adipose tissue the culprit? (English)

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12 August 2017

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Keith N Frayn

1

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12 August 2017

1 February 2005

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Proceedings of the Nutrition Society

12 August 2017

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12 August 2017

64

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12 August 2017

1

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12 August 2017

7-13

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Leptin inhibits insulin secretion and reduces insulin mRNA levels in rat isolated pancreatic islets

12 August 2017

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Serum immunoreactive-leptin concentrations in normal-weight and obese humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Leptin-replacement therapy for lipodystrophy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Plasma free fatty acid concentrations in obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Positional cloning of the mouse obese gene and its human homologue

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Insulin sensitivity index, acute insulin response, and glucose effectiveness in a population-based sample of 380 young healthy Caucasians. Analysis of the impact of gender, body fat, physical fitness, and life-style factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The role of non-esterified fatty acids in the deterioration of glucose tolerance in Caucasian subjects: results of the Paris Prospective Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Subcutaneous adipose tissue releases interleukin-6, but not tumor necrosis factor-alpha, in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Chronic leptin treatment enhances insulin-stimulated glucose disposal in skeletal muscle of high-fat fed rodents

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Diet-induced insulin resistance in mice lacking adiponectin/ACRP30

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Increased beta -oxidation but no insulin resistance or glucose intolerance in mice lacking adiponectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Mechanisms of fatty acid-induced inhibition of glucose uptake

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The impairment in endothelial function induced by non-esterified fatty acids can be reversed by insulin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Hypoadiponectinemia in obesity and type 2 diabetes: close association with insulin resistance and hyperinsulinemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Obesity is associated with macrophage accumulation in adipose tissue

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Defects of insulin action on fatty acid and carbohydrate metabolism in familial combined hyperlipidemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Disruption of adiponectin causes insulin resistance and neointimal formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Subcutaneous abdominal adipose tissue blood flow: variation within and between subjects and relationship to obesity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The hormone resistin links obesity to diabetes

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Muscle triglyceride and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Impaired postprandial adipose tissue blood flow response is related to aspects of insulin sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Acute interleukin-6 administration does not impair muscle glucose uptake or whole-body glucose disposal in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Relationship between blood pressure, metabolic variables and blood flow in obese subjects with or without non-insulin-dependent diabetes mellitus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Insulin control of glucose metabolism in man: a new kinetic analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

A novel serum protein similar to C1q, produced exclusively in adipocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The expression of TNF alpha by human muscle. Relationship to insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Metabolic precursors of hypertension. The San Antonio Heart Study.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Regulation of insulin sensitivity by adipose tissue-derived hormones and inflammatory cytokines

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Relation between leptin and the regulation of glucose metabolism

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Adipose tissue as a buffer for daily lipid flux

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Adipocytokines and insulin resistance

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Leptin impairs insulin signaling in rat adipocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Effect of fatty acids on glucose production and utilization in man

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Fasting plasma free fatty acids and risk of type 2 diabetes: the atherosclerosis risk in communities study

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Glucose turnover and adipose tissue lipolysis are insulin-resistant in healthy relatives of type 2 diabetes patients: is cellular insulin resistance a secondary phenomenon?

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

Acute stimulation of glucose metabolism in mice by leptin treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1079%2FPNS2004403

21 January 2018

Identifiers

DOI

10.1079/PNS2004403

1 reference

12 August 2017

1 reference

PubMed ID

15877917