TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target (Q36129955)

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English	TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target	scientific article

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31 January 2020

TRPM8 ion channel is aberrantly expressed and required for preventing replicative senescence in pancreatic adenocarcinoma: potential role of TRPM8 as a biomarker and target (English)

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31 January 2020

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pancreatic adenocarcinoma

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31 January 2020

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Nelson S Yee

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31 January 2020

Min Sun Lee

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31 January 2020

Weiqiang Zhou

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31 January 2020

Henning Gerke

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31 January 2020

Rosemary K Yee

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1 June 2012

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Cancer Biology and Therapy

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592-599

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31 January 2020

Cancer statistics, 2011: the impact of eliminating socioeconomic and racial disparities on premature cancer deaths

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2 October 2017

Transient receptor potential ion channel Trpm7 regulates exocrine pancreatic epithelial proliferation by Mg2+-sensitive Socs3a signaling in development and cancer

1 reference

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Werner syndrome as a hereditary risk factor for exocrine pancreatic cancer: potential role of WRN in pancreatic tumorigenesis and patient-tailored therapy

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2 October 2017

Transient receptor potential channel TRPM8 is over-expressed and required for cellular proliferation in pancreatic adenocarcinoma

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2 October 2017

Estrogen regulation of TRPM8 expression in breast cancer cells

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2 October 2017

Pancreatic cancer

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2 October 2017

Combined targeting of histone deacetylases and hedgehog signaling enhances cytoxicity in pancreatic cancer.

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2 October 2017

Ion channels: functional expression and therapeutic potential in cancer. Colloquium on Ion Channels and Cancer

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Diversity in the neural circuitry of cold sensing revealed by genetic axonal labeling of transient receptor potential melastatin 8 neurons

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2 October 2017

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2 October 2017

Androgen receptor blockade in experimental combination therapy of pancreatic cancer

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Prostate cell differentiation status determines transient receptor potential melastatin member 8 channel subcellular localization and function

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Bidirectional shifts of TRPM8 channel gating by temperature and chemical agents modulate the cold sensitivity of mammalian thermoreceptors.

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TRPM8 in prostate cancer cells: a potential diagnostic and prognostic marker with a secretory function?

1 reference

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2 October 2017

Novel role of cold/menthol-sensitive transient receptor potential melastatine family member 8 (TRPM8) in the activation of store-operated channels in LNCaP human prostate cancer epithelial cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408969

2 October 2017

Biophysical properties of menthol-activated cold receptor TRPM8 channels

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408969

2 October 2017

Functional control of cold- and menthol-sensitive TRPM8 ion channels by phosphatidylinositol 4,5-bisphosphate.

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2 October 2017

Evidence that TRPM8 is an androgen-dependent Ca2+ channel required for the survival of prostate cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408969

2 October 2017

The super-cooling agent icilin reveals a mechanism of coincidence detection by a temperature-sensitive TRP channel

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3408969

2 October 2017

The principle of temperature-dependent gating in cold- and heat-sensitive TRP channels

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Pathways of apoptotic and non-apoptotic death in tumour cells

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2 October 2017

TRPM8 activation by menthol, icilin, and cold is differentially modulated by intracellular pH.

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TRP channels as cellular sensors

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Clinicopathologic and molecular features of pancreatic adenocarcinoma associated with Peutz-Jeghers syndrome

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A TRP channel that senses cold stimuli and menthol

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Identification of a cold receptor reveals a general role for TRP channels in thermosensation

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Trp-p8, a novel prostate-specific gene, is up-regulated in prostate cancer and other malignancies and shares high homology with transient receptor potential calcium channel proteins.

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2 October 2017

Tissue distribution profiles of the human TRPM cation channel family.

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23 September 2018

Evidence for specific TRPM8 expression in human prostate secretory epithelial cells: functional androgen receptor requirement.

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23 September 2018

PI(4,5)P2 regulates the activation and desensitization of TRPM8 channels through the TRP domain

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23 September 2018

Zebrafish as a model for pancreatic cancer research.

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23 September 2018

Ca2+ pools and cell growth. Evidence for sarcoendoplasmic Ca2+-ATPases 2B involvement in human prostate cancer cell growth control

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Requirement of Ras-GTP-Raf Complexes for Activation of Raf-1 by Protein Kinase C

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10.4161/CBT.20079

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31 January 2020

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Europe PubMed Central

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31 January 2020

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31 January 2020

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