Role of endothelin in fibrosis and anti-fibrotic potential of bosentan (Q36132271)

12 August 2017

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title

Role of endothelin in fibrosis and anti-fibrotic potential of bosentan (English)

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12 August 2017

Martine Clozel

1

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12 August 2017

Hashem Salloukh

series ordinal

2

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12 August 2017

language of work or name

English

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publication date

1 January 2005

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12 August 2017

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12 August 2017

volume

37

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12 August 2017

issue

1

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12 August 2017

page(s)

2-12

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Endothelin-1 transgenic mice develop glomerulosclerosis, interstitial fibrosis, and renal cysts but not hypertension.

12 August 2017

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Endothelin, an endothelial-dependent vasoconstrictor in scleroderma. Enhanced production and profibrotic action

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Endothelin-1 and endothelin-3 induce chemotaxis and replication of pulmonary artery fibroblasts

21 January 2018

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21 January 2018

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21 January 2018

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Synergistic effects of endothelin-1 (ET-1) and transforming growth factor alpha (TGF-alpha) or epidermal growth factor (EGF) on DNA replication and G1 to S phase transition

21 January 2018

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Nephroprotective effect of bosentan in diabetic rats

21 January 2018

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Familial primary pulmonary hypertension (gene PPH1) is caused by mutations in the bone morphogenetic protein receptor-II gene

21 January 2018

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Primary pulmonary hypertension is associated with reduced pulmonary vascular expression of type II bone morphogenetic protein receptor

21 January 2018

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Altered growth responses of pulmonary artery smooth muscle cells from patients with primary pulmonary hypertension to transforming growth factor-beta(1) and bone morphogenetic proteins

21 January 2018

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Functional analysis of bone morphogenetic protein type II receptor mutations underlying primary pulmonary hypertension

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Differential activation of NF-kappa B and AP-1 in increased fibronectin synthesis in target organs of diabetic complications

21 January 2018

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Expression of endothelin-1 in the lungs of patients with pulmonary hypertension.

21 January 2018

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Experimental bronchiolitis obliterans induced by in vivo HVJ-liposome-mediated endothelin-1 gene transfer

21 January 2018

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Amiodarone pulmonary toxicity: cytopathology, ultrastructure, and immunocytochemistry

21 January 2018

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Amiodarone pulmonary, neuromuscular and ophthalmological toxicity

21 January 2018

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Interaction of endothelin-3 with endothelin-B receptor is essential for development of epidermal melanocytes and enteric neurons

21 January 2018

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Role of endogenous endothelin in chronic heart failure: effect of long-term treatment with an endothelin antagonist on survival, hemodynamics, and cardiac remodeling

21 January 2018

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Cardiac fibrosis occurs early and involves endothelin and AT-1 receptors in hypertension due to endogenous angiotensin II.

21 January 2018

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Contributions of endothelin-1 and sodium hydrogen exchanger-1 in the diabetic myocardium.

21 January 2018

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Losartan but not verapamil inhibits angiotensin II-induced tissue endothelin-1 increase: role of blood pressure and endothelial function

21 January 2018

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Molecular basis of renal fibrosis

21 January 2018

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Nitric oxide inhibition induces early activation of type I collagen gene in renal resistance vessels and glomeruli in transgenic mice. Role of endothelin

21 January 2018

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Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis

21 January 2018

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Molecular mechanisms of liver fibrogenesis--a homage to the role of activated fat-storing cells

21 January 2018

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Endothelin stimulates transforming growth factor-beta1 and collagen synthesis in stellate cells from control but not cirrhotic rat liver

21 January 2018

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Characterization of endothelin receptors mediating rat hepatic stellate cell contraction

21 January 2018

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Enhanced expression of endothelin receptor subtypes in cirrhotic rat liver

21 January 2018

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Endothelin induced contractility of stellate cells from normal and cirrhotic rat liver: implications for regulation of portal pressure and resistance

21 January 2018

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Beneficial hemodynamic effects of bosentan, a mixed ET(A) and ET(B) receptor antagonist, in portal hypertensive rats.

21 January 2018

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Apoptotic germ-cell death and testicular damage in experimental diabetes: prevention by endothelin antagonism.

21 January 2018

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Successful treatment of systemic sclerosis digital ulcers and pulmonary arterial hypertension with endothelin receptor antagonist bosentan.

21 January 2018

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ETA receptor blockade induces fibrosis of the clipped kidney in two-kidney-one-clip renovascular hypertensive rats

21 January 2018

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Endothelin System–Dependent Cardiac Remodeling in Renovascular Hypertension

21 January 2018

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Pathogenesis of interstitial fibrosis in chronic purine aminonucleoside nephrosis

21 January 2018

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An oral endothelin-A receptor antagonist blocks collagen synthesis and deposition in advanced rat liver fibrosis

21 January 2018

1 reference

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10.1080/07853890410018925

21 January 2018

Identifiers

DOI

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12 August 2017

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