Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II. (Q36136076)

12 August 2017

Anti-proliferative effects of simocyclinone D8 (SD8), a novel catalytic inhibitor of topoisomerase II. (English)

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12 August 2017

Ahad A Sadiq

1

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12 August 2017

Manish R Patel

2

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12 August 2017

Blake A Jacobson

3

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12 August 2017

Marco Escobedo

4

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12 August 2017

Keith Ellis

5

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12 August 2017

Lisa M Oppegard

6

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12 August 2017

Hiroshi Hiasa

7

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12 August 2017

Robert A Kratzke

8

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12 August 2017

10 January 2009

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Investigational New Drugs

12 August 2017

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12 August 2017

28

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12 August 2017

20-25

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12 August 2017

1

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https://scigraph.springernature.com/pub.10.1007/s10637-008-9209-1

12 August 2017

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cites work

HER-2 and topoisomerase II as predictors of response to chemotherapy

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Acridine-based agents with topoisomerase II activity inhibit pancreatic cancer cell proliferation and induce apoptosis

2 October 2017

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Ras pathway activation in malignant mesothelioma

2 October 2017

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Roles of DNA topoisomerase II isozymes in chemotherapy and secondary malignancies.

2 October 2017

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New agents in the management of advanced mesothelioma.

2 October 2017

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Catalytic topoisomerase II inhibitors in cancer therapy.

2 October 2017

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Comparison of four chemotherapy regimens for advanced non-small-cell lung cancer

2 October 2017

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Phase I and pharmacokinetic study of the topoisomerase II catalytic inhibitor fostriecin.

2 October 2017

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Response to ICRF-159 in cell lines resistant to cleavable complex-forming topoisomerase II inhibitors

2 October 2017

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Reconstituted basement membrane (matrigel) and laminin can enhance the tumorigenicity and the drug resistance of small cell lung cancer cell lines

2 October 2017

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Merbarone, a catalytic inhibitor of DNA topoisomerase II, induces apoptosis in CEM cells through activation of ICE/CED-3-like protease.

2 October 2017

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Induction of apoptosis by depletion of DNA topoisomerase IIalpha in mammalian cells

2 July 2018

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Topoisomerase inhibitor-induced apoptosis accompanied by down-regulation of Bcl-2 in human lung cancer cells.

23 September 2018

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Phase II trial of pegylated-liposomal doxorubicin (Doxil) in mesothelioma

23 September 2018

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Simocyclinones, novel cytostatic angucyclinone antibiotics produced by Streptomyces antibioticus Tü 6040. I. Taxonomy, fermentation, isolation and biological activities.

23 September 2018

1 reference

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Topoisomerase II inhibitor-induced apoptosis in thymocytes and lymphoma cells

23 September 2018

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12 December 2020

Mechanism of action of eukaryotic topoisomerase II and drugs targeted to the enzyme

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12 December 2020

Clinical applications of anticancer drugs targeted to topoisomerase II

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12 December 2020

Apoptosis without decrease of cell DNA content

1 reference

12 December 2020

10.1007/S10637-008-9209-1

Identifiers

DOI

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12 August 2017

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12 August 2017

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