High levels of MDM2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines (Q36136488)

12 August 2017

High levels of MDM2 are not correlated with the presence of wild-type p53 in human malignant mesothelioma cell lines (English)

1 reference

12 August 2017

S Ungar

1

1 reference

12 August 2017

A Van de Meeren

2

1 reference

12 August 2017

L Tammilehto

3

1 reference

12 August 2017

K Linnainmaa

4

1 reference

12 August 2017

K Mattson

5

1 reference

12 August 2017

B I Gerwin

6

1 reference

12 August 2017

language of work or name

English

0 references

publication date

1 November 1996

1 reference

British Journal of Cancer

12 August 2017

1 reference

12 August 2017

74

1 reference

12 August 2017

10

1 reference

12 August 2017

1534-1540

1 reference

https://scigraph.springernature.com/pub.10.1038/bjc.1996.585

12 August 2017

0 references

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mdm2 expression is induced by wild type p53 activity

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The mdm-2 oncogene can overcome wild-type p53 suppression of transformed cell growth

2 October 2017

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Functional interactions of the retinoblastoma protein with mammalian D-type cyclins

2 October 2017

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Sequence-specific DNA binding by p53: identification of target sites and lack of binding to p53 - MDM2 complexes

2 October 2017

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The p53-mdm-2 autoregulatory feedback loop

2 October 2017

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Physical and functional interaction between wild-type p53 and mdm2 proteins

2 October 2017

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The mdm-2 gene is induced in response to UV light in a p53-dependent manner

2 October 2017

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Mutations and altered expression of p16INK4 in human cancer.

2 October 2017

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Regulation of mdm2 expression by p53: alternative promoters produce transcripts with nonidentical translation potential

2 October 2017

1 reference

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Interaction between the retinoblastoma protein and the oncoprotein MDM2

2 October 2017

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Stimulation of E2F1/DP1 transcriptional activity by MDM2 oncoprotein

2 October 2017

1 reference

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Mapping of the p53 and mdm-2 interaction domains

2 October 2017

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A functional p53-responsive intronic promoter is contained within the human mdm2 gene

2 October 2017

1 reference

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The p53-mdm2 autoregulatory feedback loop: a paradigm for the regulation of growth control by p53?

2 October 2017

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The pathogenesis of asbestos-associated diseases

2 October 2017

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Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

2 October 2017

1 reference

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Mesotheliomas in rats following inoculation with asbestos

2 October 2017

1 reference

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Alteration of superoxide dismutase activity in tracheal epithelial cells by asbestos and inhibition of cytotoxicity by antioxidants

2 October 2017

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Molecular analysis and chromosomal mapping of amplified genes isolated from a transformed mouse 3T3 cell line

2 October 2017

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Asbestos-associated chromosomal changes in human mesothelial cells

2 October 2017

1 reference

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Various rat adult tissues express only one major mRNA species from the glyceraldehyde-3-phosphate-dehydrogenase multigenic family

2 October 2017

1 reference

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Association between an oncogene and an anti-oncogene: the adenovirus E1A proteins bind to the retinoblastoma gene product

2 October 2017

1 reference

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SV40 large tumor antigen forms a specific complex with the product of the retinoblastoma susceptibility gene

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

The human papilloma virus-16 E7 oncoprotein is able to bind to the retinoblastoma gene product

2 October 2017

1 reference

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Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

2 October 2017

1 reference

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Role of the retinoblastoma gene in the initiation and progression of human cancer

2 October 2017

1 reference

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The p53 tumour suppressor gene

2 October 2017

1 reference

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Tumorigenic potential associated with enhanced expression of a gene that is amplified in a mouse tumor cell line

2 October 2017

1 reference

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p53 mutations in human cancers

2 October 2017

1 reference

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Amplification of a gene encoding a p53-associated protein in human sarcomas

2 October 2017

1 reference

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Enhanced binding of a 95 kDa protein to p53 in cells undergoing p53-mediated growth arrest

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Inhibition of p53 transactivation required for transformation by adenovirus early 1B protein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

p53 function and dysfunction

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

The transcriptional transactivation function of wild-type p53 is inhibited by SV40 large T-antigen and by HPV-16 E6 oncoprotein

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Wild-type p53 is a cell cycle checkpoint determinant following irradiation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Amplification and overexpression of the MDM2 gene in a subset of human malignant gliomas without p53 mutations.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

SV40 T antigen abrogates p53-mediated transcriptional activity.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Differential induction of transcriptionally active p53 following UV or ionizing radiation: defects in chromosome instability syndromes?

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Identification and characterization of multiple mdm-2 proteins and mdm-2-p53 protein complexes.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Differential responses to growth factors by normal human mesothelial cultures from individual donors.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

p53 and Kirsten-ras mutations in human mesothelioma cell lines

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Simian virus 40-like DNA sequences in human pleural mesothelioma.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

Overexpression of the MDM2 gene by childhood acute lymphoblastic leukemia cells expressing the wild-type p53 gene.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2074839

MDM2 gene amplification in metastatic osteosarcoma

23 September 2018

1 reference

12 December 2020

The human MDM-2 oncogene is overexpressed in leukemias

1 reference

12 December 2020

Differential immunohistochemical staining for retinoblastoma protein with the antibodies C15 and 1F8 in malignant mesothelioma

1 reference

12 December 2020

p53 Mutation and MDM2 amplification in human soft tissue sarcomas

1 reference

12 December 2020

Chrysotile fiber is a strong mutagen in mammalian cells

1 reference

12 December 2020

Over-expression of the MDM2 gene is found in some cases of haematological malignancies.

1 reference

12 December 2020

p16 alterations and deletion mapping of 9p21-p22 in malignant mesothelioma

1 reference

12 December 2020

Differential expression of multiple MDM2 messenger RNAs and proteins in normal and tumorigenic breast epithelial cells

1 reference

12 December 2020

No room at the p53 inn

1 reference

12 December 2020

mdm2 gene amplification and overexpression in non-small cell lung carcinomas with accumulation of the p53 protein in the absence of p53 gene mutations

1 reference

12 December 2020

Codeletion of p15 and p16 genes in primary non-small cell lung carcinoma

1 reference

12 December 2020

Immunoreactivity for p53 and mdm2 and the detection of p53 mutations in human malignant mesothelioma

1 reference

12 December 2020

Wild-type p53 activates transcription in vitro

1 reference

12 December 2020

Molecular abnormalities of mdm2 and p53 genes in adult soft tissue sarcomas

1 reference

12 December 2020

Enhanced translation: a novel mechanism of mdm2 oncogene overexpression identified in human tumor cells

1 reference

12 December 2020

Identifiers

DOI

10.1038/BJC.1996.585

1 reference

12 August 2017

1 reference

12 August 2017

PubMed publication ID

8932331

1 reference