Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation (Q36140425)

12 August 2017

Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation (English)

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Dermatophagoides pteronyssinus

12 August 2017

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1 reference

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Ginger L Milne

6

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author name string

Tao Liu

1

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12 August 2017

Tanya M Laidlaw

2

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12 August 2017

Chunli Feng

3

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12 August 2017

Wei Xing

4

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12 August 2017

Shiliang Shen

5

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12 August 2017

Joshua A Boyce

7

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12 August 2017

language of work or name

English

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publication date

16 July 2012

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12 August 2017

6

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Proceedings of the National Academy of Sciences of the United States of America

inferred from page(s)

published in

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12 August 2017

109

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12 August 2017

31

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12 August 2017

12692-12697

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Prostaglandin E(2) produced by the lung augments the effector phase of allergic inflammation

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Cysteinyl leukotriene overproduction in aspirin-exacerbated respiratory disease is driven by platelet-adherent leukocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

The purinergic G protein-coupled receptor 6 inhibits effector T cell activation in allergic pulmonary inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Milrinone attenuates thromboxane receptor-mediated hyperresponsiveness in hypoxic pulmonary arterial myocytes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Dectin-2 mediates Th2 immunity through the generation of cysteinyl leukotrienes

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Prostaglandin E(2) exerts homeostatic regulation of pulmonary vascular remodeling in allergic airway inflammation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Prostaglandin E2-EP4 signaling promotes immune inflammation through Th1 cell differentiation and Th17 cell expansion

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Prostanoids in health and disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Induction of vascular remodeling in the lung by chronic house dust mite exposure

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Pulmonary arterial remodeling induced by a Th2 immune response

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Facilitation of Th1-mediated immune response by prostaglandin E receptor EP1.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Prostaglandin E receptors

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Complete reversal of acid-induced acute lung injury by blocking of platelet-neutrophil aggregation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Aspirin-sensitive rhinosinusitis is associated with reduced E-prostanoid 2 receptor expression on nasal mucosal inflammatory cells

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Cellular prostaglandin E2 production by membrane-bound prostaglandin E synthase-2 via both cyclooxygenases-1 and -2.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Deficient prostaglandin E2 production by bronchial fibroblasts of asthmatic patients, with special reference to aspirin-induced asthma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Early effects of aspirin desensitization treatment in asthmatic patients with aspirin-exacerbated respiratory disease

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Function of prostanoid receptors: studies on knockout mice

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

The safety of celecoxib in patients with aspirin-sensitive asthma

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Molecular identification of cytosolic prostaglandin E2 synthase that is functionally coupled with cyclooxygenase-1 in immediate prostaglandin E2 biosynthesis

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Deletion of microsomal prostaglandin E2 (PGE2) synthase-1 reduces inducible and basal PGE2 production and alters the gastric prostanoid profile

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Differential metabolism of arachidonic acid in nasal polyp epithelial cells cultured from aspirin-sensitive and aspirin-tolerant patients

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Stimulation with thromboxane A2 (TXA2) receptor agonist enhances ICAM-1, VCAM-1 or ELAM-1 expression by human vascular endothelial cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Effect of an inhaled thromboxane mimetic (U46619) on airway function in human subjects

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Analgesic effectiveness of celecoxib and diclofenac in patients with osteoarthritis of the hip requiring joint replacement surgery: a 12-week, multicenter, randomized, double-blind, parallel-group, double-dummy, noninferiority study

2 July 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

NSAIDs and risk of lower gastrointestinal bleeding

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Lipopolysaccharide-dependent prostaglandin E(2) production is regulated by the glutathione-dependent prostaglandin E(2) synthase gene induced by the Toll-like receptor 4/MyD88/NF-IL6 pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Prostaglandin E2 protects lower airways against bronchoconstriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

The immunomodulatory actions of prostaglandin E2 on allergic airway responses in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Correlation between the prostaglandin D(2)/E(2) ratio in nasal polyps and the recalcitrant pathophysiology of chronic rhinosinusitis associated with bronchial asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Reduced expression of the prostaglandin E2 receptor E-prostanoid 2 on bronchial mucosal leukocytes in patients with aspirin-sensitive asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Thromboxane A(2) receptors mediate pulmonary hypertension in 60% oxygen-exposed newborn rats by a cyclooxygenase-independent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Thromboxane A2 induces airway constriction through an M3 muscarinic acetylcholine receptor-dependent mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Suppression of allergic inflammation by the prostaglandin E receptor subtype EP3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Prostaglandin E2-prostanoid EP3 signal induces vascular contraction via nPKC and ROCK activation in rat mesenteric artery.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Regulation of the human prostanoid TPalpha and TPbeta receptor isoforms mediated through activation of the EP(1) and IP receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Receptors and pathways mediating the effects of prostaglandin E2 on airway tone

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1207816109

Prostaglandin E2 and cysteinyl leukotriene concentrations in sputum: association with asthma severity and eosinophilic inflammation

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Increased prostaglandin E2 levels in the airway of patients with eosinophilic bronchitis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3411985

Interaction of PGH synthase isozymes-1 and -2 with nonsteroidal anti-inflammatory drugs

23 September 2018

1 reference

12 December 2020

A genetic approach for studying the role of thromboxane A2 in the kidney

1 reference

12 December 2020

Effects of thromboxane A2 antagonist on airway hyperresponsiveness, exhaled nitric oxide, and induced sputum eosinophils in asthmatics

1 reference

12 December 2020

Protective effects of inhaled PGE2 on allergen-induced airway responses and airway inflammation

1 reference

12 December 2020

Effect of AA-2414, a thromboxane A2 receptor antagonist, on airway inflammation in subjects with asthma

1 reference

12 December 2020

Cyclooxygenase-2 mRNA is downexpressed in nasal polyps from aspirin-sensitive asthmatics

1 reference

12 December 2020

Platelet P-selectin is required for pulmonary eosinophil and lymphocyte recruitment in a murine model of allergic inflammation

1 reference

12 December 2020

Thromboxane hypersensitivity in hypoxic pulmonary artery myocytes: altered TP receptor localization and kinetics

1 reference

12 December 2020

Cysteinyl leukotrienes overproduction and mast cell activation in aspirin-provoked bronchospasm in asthma

1 reference

12 December 2020

BAY u3405, a thromboxane A2 antagonist, reduces bronchial hyperresponsiveness in asthmatics

1 reference

12 December 2020

Concordant induction of prostaglandin E2 synthase with cyclooxygenase-2 leads to preferred production of prostaglandin E2 over thromboxane and prostaglandin D2 in lipopolysaccharide-stimulated rat peritoneal macrophages

1 reference

12 December 2020

Thromboxane A2 induces cell signaling but requires platelet-derived growth factor to act as a mitogen

1 reference

12 December 2020

PGE1 and PGE2 modify platelet function through different prostanoid receptors

1 reference

12 December 2020

Reduced expression of COXs and production of prostaglandin E2 in patients with nasal polyps with or without aspirin-intolerant asthma

1 reference

12 December 2020

The Th2 lymphocyte products IL-4 and IL-13 rapidly induce airway hyperresponsiveness through direct effects on resident airway cells

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1207816109

1 reference

12 August 2017

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1 reference

12 August 2017

PubMed publication ID

22802632

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