Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways. (Q36145284)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22766885%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

title

Saturated fatty acids activate TLR-mediated proinflammatory signaling pathways (English)

1 reference

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7 February 2020

0 references

0 references

3

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7 February 2020

Dina A Schneider

5

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7 February 2020

John W Newman

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7 February 2020

Sean H Adams

7

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7 February 2020

author name string

Shurong Huang

1

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7 February 2020

Jennifer M Rutkowsky

2

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7 February 2020

Kikumi D Ono-Moore

4

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7 February 2020

Daniel H Hwang

8

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7 February 2020

publication date

4 July 2012

1 reference

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Journal of Lipid Research

7 February 2020

published in

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7 February 2020

volume

53

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7 February 2020

page(s)

2002-2013

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7 February 2020

issue

9

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Inflammation and lipid signaling in the etiology of insulin resistance

7 February 2020

cites work

1 reference

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Lipid-induced insulin resistance mediated by the proinflammatory receptor TLR4 requires saturated fatty acid-induced ceramide biosynthesis in mice

2 October 2017

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2 October 2017

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2 October 2017

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Fatty acids modulate Toll-like receptor 4 activation through regulation of receptor dimerization and recruitment into lipid rafts in a reactive oxygen species-dependent manner

2 October 2017

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NADPH oxidase 2 interaction with TLR2 is required for efficient innate immune responses to mycobacteria via cathelicidin expression

2 October 2017

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2 October 2017

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Silica crystals and aluminum salts activate the NALP3 inflammasome through phagosomal destabilization

2 October 2017

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A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways

2 October 2017

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Crystal structure of the TLR1-TLR2 heterodimer induced by binding of a tri-acylated lipopeptide

2 October 2017

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Differential modulation of Nods signaling pathways by fatty acids in human colonic epithelial HCT116 cells

2 October 2017

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Lipid rafts, detergent-resistant membranes, and raft targeting signals

2 October 2017

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Role of the Toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages

2 October 2017

1 reference

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TLR4 links innate immunity and fatty acid-induced insulin resistance

2 October 2017

1 reference

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Carbon monoxide differentially inhibits TLR signaling pathways by regulating ROS-induced trafficking of TLRs to lipid rafts

2 October 2017

1 reference

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Oxidative stress generated by hemorrhagic shock recruits Toll-like receptor 4 to the plasma membrane in macrophages

2 October 2017

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Proteomic analysis of SUMO4 substrates in HEK293 cells under serum starvation-induced stress

2 October 2017

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Saturated fatty acid activates but polyunsaturated fatty acid inhibits Toll-like receptor 2 dimerized with Toll-like receptor 6 or 1.

2 October 2017

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Recombinant human heat shock protein 60 does not induce the release of tumor necrosis factor alpha from murine macrophages

2 October 2017

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Differential modulation of Toll-like receptors by fatty acids: preferential inhibition by n-3 polyunsaturated fatty acids

2 October 2017

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Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4.

2 October 2017

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The repertoire for pattern recognition of pathogens by the innate immune system is defined by cooperation between toll-like receptors

2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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Absence of Tlr2 protects against high-fat diet-induced inflammation and results in greater insulin-stimulated glucose transport in cultured adipocytes

2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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Toll-like receptor 2-deficient mice are protected from insulin resistance and beta cell dysfunction induced by a high-fat diet.

2 July 2018

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Lipoteichoic acid induces HO-1 expression via the TLR2/MyD88/c-Src/NADPH oxidase pathway and Nrf2 in human tracheal smooth muscle cells

23 September 2018

1 reference

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Tlr-4 deficiency selectively protects against obesity induced by diets high in saturated fat.

23 September 2018

1 reference

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A role for ceramide, but not diacylglycerol, in the antagonism of insulin signal transduction by saturated fatty acids

23 September 2018

1 reference

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Toll-like receptor-4 mediates vascular inflammation and insulin resistance in diet-induced obesity

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22766885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Saturated fatty acids do not directly stimulate Toll-like receptor signaling

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22766885

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1194/JLR.D029546

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22766885%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22766885%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference