Process or perish: quality control in mRNA biogenesis (Q36149583)

12 August 2017

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title

Process or perish: quality control in mRNA biogenesis (English)

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12 August 2017

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2

Anita H Corbett

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12 August 2017

Milo B Fasken

1

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12 August 2017

1 June 2005

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Nature Structural & Molecular Biology

12 August 2017

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12 August 2017

12

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12 August 2017

6

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12 August 2017

482-488

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https://scigraph.springernature.com/pub.10.1038/nsmb945

12 August 2017

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Nuclear retention of unspliced mRNAs in yeast is mediated by perinuclear Mlp1.

21 January 2018

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The C-terminal domain of myosin-like protein 1 (Mlp1p) is a docking site for heterogeneous nuclear ribonucleoproteins that are required for mRNA export

21 January 2018

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Perinuclear Mlp proteins downregulate gene expression in response to a defect in mRNA export

21 January 2018

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Guardian at the gate: preventing unspliced pre-mRNA export

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Peering through the Pore

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The link between mRNA processing and transcription: communication works both ways

21 January 2018

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The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay

21 January 2018

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The interplay of nuclear mRNP assembly, mRNA surveillance and export

21 January 2018

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Early formation of mRNP: license for export or quality control?

21 January 2018

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Nucleocytoplasmic transport: integrating mRNA production and turnover with export through the nuclear pore

21 January 2018

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Coupling transcription, splicing and mRNA export

21 January 2018

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Formation of cytoplasmic heat shock granules in tomato cell cultures and leaves

21 January 2018

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RNA-binding proteins TIA-1 and TIAR link the phosphorylation of eIF-2 alpha to the assembly of mammalian stress granules

21 January 2018

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Localization and translation of mRNA in dendrites and axons

21 January 2018

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The yin and yang of the exosome

21 January 2018

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The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases

21 January 2018

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The exosome: a proteasome for RNA?

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Interactions between mRNA export commitment, 3'-end quality control, and nuclear degradation

21 January 2018

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Localization of nuclear retained mRNAs in Saccharomyces cerevisiae

21 January 2018

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Rrp6p, the yeast homologue of the human PM-Scl 100-kDa autoantigen, is essential for efficient 5.8 S rRNA 3' end formation

21 January 2018

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21 January 2018

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A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3p

21 January 2018

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Identification of a regulated pathway for nuclear pre-mRNA turnover.

21 January 2018

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Quality control of mRNA 3'-end processing is linked to the nuclear exosome

21 January 2018

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Stable mRNP formation and export require cotranscriptional recruitment of the mRNA export factors Yra1p and Sub2p by Hpr1p

21 January 2018

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21 January 2018

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Friedrich Miescher Prize awardee lecture review. A conserved family of nuclear export receptors mediates the exit of messenger RNA to the cytoplasm.

21 January 2018

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Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex

21 January 2018

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mRNA export: an assembly line from genes to nuclear pores

21 January 2018

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Quality control of messenger ribonucleoprotein particles in the nucleus and at the pore

21 January 2018

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Formation of export-competent mRNP: escaping nuclear destruction

21 January 2018

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Dynamics of transcription and mRNA export

21 January 2018

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Proteins connecting the nuclear pore complex with the nuclear interior

21 January 2018

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Identification of protein p270/Tpr as a constitutive component of the nuclear pore complex-attached intranuclear filaments

21 January 2018

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Mlp2p, a component of nuclear pore attached intranuclear filaments, associates with nic96p.

21 January 2018

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Functional analysis of Tpr: identification of nuclear pore complex association and nuclear localization domains and a role in mRNA export

21 January 2018

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A cooperative interaction between U2AF65 and mBBP/SF1 facilitates branchpoint region recognition

21 January 2018

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Mechanistic links between nonsense-mediated mRNA decay and pre-mRNA splicing in mammalian cells

21 January 2018

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Gene products that promote mRNA turnover in Saccharomyces cerevisiae

21 January 2018

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Evidence that phosphorylation of human Upfl protein varies with intracellular location and is mediated by a wortmannin-sensitive and rapamycin-sensitive PI 3-kinase-related kinase signaling pathway

21 January 2018

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Characterization of human Smg5/7a: a protein with similarities to Caenorhabditis elegans SMG5 and SMG7 that functions in the dephosphorylation of Upf1.

21 January 2018

1 reference

Phosphorylation of hUPF1 induces formation of mRNA surveillance complexes containing hSMG-5 and hSMG-7

21 January 2018

1 reference

SMG7 is a 14-3-3-like adaptor in the nonsense-mediated mRNA decay pathway

21 January 2018

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SMG7 acts as a molecular link between mRNA surveillance and mRNA decay

21 January 2018

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Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans

21 January 2018

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Aberrant mRNAs with extended 3' UTRs are substrates for rapid degradation by mRNA surveillance

21 January 2018

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The RNA binding protein Pub1 modulates the stability of transcripts containing upstream open reading frames

21 January 2018

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An internal open reading frame triggers nonsense-mediated decay of the yeast SPT10 mRNA.

21 January 2018

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Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon-exon junction complex

21 January 2018

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Identification and characterization of human orthologues to Saccharomyces cerevisiae Upf2 protein and Upf3 protein (Caenorhabditis elegans SMG-4)

21 January 2018

1 reference

Communication of the position of exon-exon junctions to the mRNA surveillance machinery by the protein RNPS1

21 January 2018

1 reference

The structural basis for the interaction between nonsense-mediated mRNA decay factors UPF2 and UPF3

21 January 2018

1 reference

Mammalian Staufen1 recruits Upf1 to specific mRNA 3'UTRs so as to elicit mRNA decay

21 January 2018

1 reference

Nonsense-containing mRNAs that accumulate in the absence of a functional nonsense-mediated mRNA decay pathway are destabilized rapidly upon its restitution

21 January 2018

1 reference

Computational modeling and experimental analysis of nonsense-mediated decay in yeast

21 January 2018

1 reference

Characterization of cis-acting sequences and decay intermediates involved in nonsense-mediated mRNA turnover

21 January 2018

1 reference

Deadenylation of the unstable mRNA encoded by the yeast MFA2 gene leads to decapping followed by 5'-->3' digestion of the transcript

21 January 2018

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An NMD pathway in yeast involving accelerated deadenylation and exosome-mediated 3'-->5' degradation

21 January 2018

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Nonsense-mediated messenger RNA decay is initiated by endonucleolytic cleavage in Drosophila

21 January 2018

1 reference

A link between RNA interference and nonsense-mediated decay in Caenorhabditis elegans

21 January 2018

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Mammalian heat shock p70 and histone H4 transcripts, which derive from naturally intronless genes, are immune to nonsense-mediated decay

21 January 2018

1 reference

Nonsense-mediated mRNA decay: molecular insights and mechanistic variations across species

21 January 2018

1 reference

Hrp1, a sequence-specific RNA-binding protein that shuttles between the nucleus and the cytoplasm, is required for mRNA 3'-end formation in yeast

21 January 2018

1 reference

The ever-increasing complexities of the exon junction complex

21 January 2018

1 reference

5' exon interactions within the human spliceosome establish a framework for exon junction complex structure and assembly

21 January 2018

1 reference

A rule for termination-codon position within intron-containing genes: when nonsense affects RNA abundance

21 January 2018

1 reference

Evidence for a pioneer round of mRNA translation: mRNAs subject to nonsense-mediated decay in mammalian cells are bound by CBP80 and CBP20

21 January 2018

1 reference

Nonsense-mediated decay does not occur within the yeast nucleus

21 January 2018

1 reference

Does protein synthesis occur in the nucleus?

21 January 2018

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Nuclear translation: what is the evidence?

21 January 2018

1 reference

An mRNA surveillance mechanism that eliminates transcripts lacking termination codons

21 January 2018

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Exosome-mediated recognition and degradation of mRNAs lacking a termination codon

21 January 2018

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The enzymes and control of eukaryotic mRNA turnover

21 January 2018

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Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiae

21 January 2018

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Polyadenylation of rRNA in Saccharomyces cerevisiae.

21 January 2018

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Molecular biology. A place to die, a place to sleep.

21 January 2018

1 reference

Separable roles for rent1/hUpf1 in altered splicing and decay of nonsense transcripts

21 January 2018

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The exon junction complex is detected on CBP80-bound but not eIF4E-bound mRNA in mammalian cells: dynamics of mRNP remodeling

21 January 2018

1 reference

The mRNA surveillance protein hSMG-1 functions in genotoxic stress response pathways in mammalian cells

21 January 2018

1 reference

Molecular biology. Skiing toward nonstop mRNA decay

21 January 2018

1 reference

The eukaryotic gene transcription machinery

31 March 2020

1 reference

The yeast hnRNP-like protein Hrp1/Nab4 marks a transcript for nonsense-mediated mRNA decay

31 March 2020

1 reference

Degradation of mRNA in eukaryotes

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

A new yeast gene with a myosin-like heptad repeat structure.

1 reference

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NSMB945

1 reference

release_fgawcjil7fazlhpw7yqjkwjdnu

12 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fgawcjil7fazlhpw7yqjkwjdnu

mapped directly with Wikidata item

24 November 2022

based on heuristic

PubMed ID

15933735

1 reference

PubMed ID

15933735