Antimalarial drugs: QT prolongation and cardiac arrhythmias (Q36150536)

12 August 2017

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title

Antimalarial drugs: QT prolongation and cardiac arrhythmias (English)

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12 August 2017

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Martin Traebert

1

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12 August 2017

Berengere Dumotier

series ordinal

2

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12 August 2017

language of work or name

English

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publication date

1 May 2005

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Expert Opinion on Drug Safety

12 August 2017

published in

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12 August 2017

volume

4

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12 August 2017

issue

3

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12 August 2017

page(s)

421-431

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Safety evaluation of the drugs available to prevent malaria

12 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

New Antimalarials A Risk-Benefit Analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Positional cloning of a novel potassium channel gene: KVLQT1 mutations cause cardiac arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

A family of potassium channel genes related to eag in Drosophila and mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

IKr channel blockers: novel antiarrhythmic agents

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Block of HERG potassium channels by the antihistamine astemizole and its metabolites desmethylastemizole and norastemizole

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

High affinity blockade of the HERG cardiac K(+) channel by the neuroleptic pimozide

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Time course and voltage dependence of expressed HERG current compared with native "rapid" delayed rectifier K current during the cardiac ventricular action potential

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

A virtual screening method for prediction of the HERG potassium channel liability of compound libraries

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Mechanisms of arsenic-induced prolongation of cardiac repolarization

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Pentamidine-induced long QT syndrome and block of hERG trafficking

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

The impact of drug-induced QT interval prolongation on drug discovery and development

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Drug-induced cardiac toxicity: emphasizing the role of electrocardiography in clinical research and drug development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

A comparison of commonly used QT correction formulae: the effect of heart rate on the QTc of normal ECGs.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Divergent proarrhythmic potential of macrolide antibiotics despite similar QT prolongation: fast phase 3 repolarization prevents early afterdepolarizations and torsade de pointes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Contributions of cellular electrophysiology to the understanding of the electrocardiogram

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

A model of the ventricular cardiac action potential. Depolarization, repolarization, and their interaction

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Blinded test in isolated female rabbit heart reliably identifies action potential duration prolongation and proarrhythmic drugs: importance of triangulation, reverse use dependence, and instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Electrophysiologic parameters and predisposing factors in the generation of drug-induced Torsade de Pointes arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Early afterdepolarizations: mechanism of induction and block. A role for L-type Ca2+ current

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Cellular basis for the normal T wave and the electrocardiographic manifestations of the long-QT syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

The M cell: its contribution to the ECG and to normal and abnormal electrical function of the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Cellular mechanisms underlying the long QT syndrome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Cellular basis for dispersion of repolarization underlying reentrant arrhythmias

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Do we understand the electrophysiologic mechanisms responsible for drug-induced cardiac arrhythmias?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Potentiation of halofantrine-induced QTc prolongation by mefloquine: correlation with blood concentrations of halofantrine

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Atovaquone-proguanil (malarone): an effective treatment for uncomplicated Plasmodium falciparum malaria in travelers from Denmark.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Long-term malaria prophylaxis for travelers

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Malaria chemoprophylaxis: when should we use it and what are the options?

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Effects of mefloquine on cardiac contractility and electrical activity in vivo, in isolated cardiac preparations, and in single ventricular myocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

The antimalarial agent mefloquine inhibits ATP-sensitive K-channels

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Primaquine therapy for malaria

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Chloroquine: mechanism of drug action and resistance in Plasmodium falciparum

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Molecular determinants of voltage-dependent human ether-a-go-go related gene (HERG) K+ channel block

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1517%2F14740338.4.3.421

21 January 2018

Identifiers

DOI

10.1517/14740338.4.3.421

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12 August 2017

1 reference