Intermolecular binding between TIFA-FHA and TIFA-pT mediates tumor necrosis factor alpha stimulation and NF-κB activation (Q36155061)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22566686%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

title

Intermolecular binding between TIFA-FHA and TIFA-pT mediates tumor necrosis factor alpha stimulation and NF-κB activation (English)

1 reference

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TRAF interacting protein with forkhead associated domain

31 January 2020

main subject

NF-κB

0 references

1 reference

protein homooligomerization

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jui-Hung Weng

2

1 reference

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31 January 2020

Pang-hung Hsu

5

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31 January 2020

Ming-Daw Tsai

13

1 reference

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31 January 2020

author name string

Chia-Chi Flora Huang

1

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31 January 2020

Tong-You Wade Wei

3

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31 January 2020

Pei-Yu Gabriel Wu

4

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31 January 2020

Yu-Hou Chen

6

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31 January 2020

Shun-Chang Wang

7

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31 January 2020

Dongyan Qin

8

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31 January 2020

Chin-Chun Hung

9

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31 January 2020

Shui-Tsung Chen

10

1 reference

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31 January 2020

Andrew H-J Wang

11

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31 January 2020

John Y-J Shyy

12

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31 January 2020

language of work or name

English

0 references

publication date

7 May 2012

1 reference

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Molecular and Cellular Biology

31 January 2020

published in

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31 January 2020

volume

32

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31 January 2020

issue

14

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31 January 2020

page(s)

2664-2673

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The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator

31 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Structural mechanism of the phosphorylation-dependent dimerization of the MDC1 forkhead-associated domain

2 October 2017

1 reference

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Structural delineation of MDC1-FHA domain binding with CHK2-pThr68

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Structural and functional analysis of phosphothreonine-dependent FHA domain interactions

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

TRAF6 is autoinhibited by an intramolecular interaction which is counteracted by trans-ubiquitination

2 October 2017

1 reference

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Structure and activation mechanism of the CHK2 DNA damage checkpoint kinase

2 October 2017

1 reference

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Dynamic and structural characterization of a bacterial FHA protein reveals a new autoinhibition mechanism

2 October 2017

1 reference

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Nanofluidic proteomic assay for serial analysis of oncoprotein activation in clinical specimens

2 October 2017

1 reference

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Structure and function of the phosphothreonine-specific FHA domain.

2 October 2017

1 reference

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Mechanistic insights into phosphoprotein-binding FHA domains.

2 October 2017

1 reference

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Isoelectric focusing technology quantifies protein signaling in 25 cells.

2 October 2017

1 reference

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TRAF6 activation of PI 3-kinase-dependent cytoskeletal changes is cooperative with Ras and is mediated by an interaction with cytoplasmic Src.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Sequential phosphorylation and multisite interactions characterize specific target recognition by the FHA domain of Ki67.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

TIFA activates IkappaB kinase (IKK) by promoting oligomerization and ubiquitination of TRAF6.

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Sequestosome 1/p62 is a polyubiquitin chain binding protein involved in ubiquitin proteasome degradation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Identification of TIFA as an adapter protein that links tumor necrosis factor receptor-associated factor 6 (TRAF6) to interleukin-1 (IL-1) receptor-associated kinase-1 (IRAK-1) in IL-1 receptor signaling

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Chk2 activation and phosphorylation-dependent oligomerization

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

2 October 2017

1 reference

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T2BP, a novel TRAF2 binding protein, can activate NF-kappaB and AP-1 without TNF stimulation

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

A diverse family of proteins containing tumor necrosis factor receptor-associated factor domains

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

The atypical PKC-interacting protein p62 channels NF-kappaB activation by the IL-1-TRAF6 pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Signaling by proinflammatory cytokines: oligomerization of TRAF2 and TRAF6 is sufficient for JNK and IKK activation and target gene induction via an amino-terminal effector domain

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Rad53 FHA domain associated with phosphorylated Rad9 in the DNA damage checkpoint

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Identification of TRAF6, a novel tumor necrosis factor receptor-associated factor protein that mediates signaling from an amino-terminal domain of the CD40 cytoplasmic region

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Discrete signaling regions in the lymphotoxin-beta receptor for tumor necrosis factor receptor-associated factor binding, subcellular localization, and activation of cell death and NF-kappaB pathways

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

CD40-tumor necrosis factor receptor-associated factor (TRAF) interactions: regulation of CD40 signaling through multiple TRAF binding sites and TRAF hetero-oligomerization

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

The FHA domain: a putative nuclear signalling domain found in protein kinases and transcription factors

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Global analysis of modifications of the human BK virus structural proteins by LC-MS/MS.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Chk2 oligomerization studied by phosphopeptide ligation: implications for regulation and phosphodependent interactions

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

Identification and characterization of Xenopus laevis homologs of mammalian TRAF6 and its binding protein TIFA.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3416184

23 September 2018

Identifiers

DOI

10.1128/MCB.00438-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22566686%20AND%20SRC:MED&resulttype=core&format=json

31 January 2020

1 reference

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31 January 2020

1 reference

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