The role of mucosal T lymphocytes in regulating intestinal inflammation (Q36164906)

12 August 2017

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title

The role of mucosal T lymphocytes in regulating intestinal inflammation (English)

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12 August 2017

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2

Fiona Powrie

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12 August 2017

Holm H Uhlig

1

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12 August 2017

publication date

15 June 2005

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Seminars in Immunopathology

12 August 2017

published in

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12 August 2017

volume

27

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12 August 2017

issue

2

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12 August 2017

page(s)

167-180

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Colitogenic Th1 cells are present in the antigen-experienced T cell pool in normal mice: control by CD4+ regulatory T cells and IL-10.

12 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

The amount of scurfin protein determines peripheral T cell number and responsiveness

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

Clustering of colonic lamina propria CD4(+) T cells to subepithelial dendritic cell aggregates precedes the development of colitis in a murine adoptive transfer model

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

Cutting edge: cure of colitis by CD4+CD25+ regulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

Regulation of murine inflammatory bowel disease by CD25+ and CD25- CD4+ glucocorticoid-induced TNF receptor family-related gene+ regulatory T cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

IL-10-secreting regulatory T cells do not express Foxp3 but have comparable regulatory function to naturally occurring CD4+CD25+ regulatory T cells

21 January 2018

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https://api.crossref.org/works/10.1007%2FS00281-005-0206-6

Role of polymorphisms in the interleukin-10 gene in determining disease susceptibility and phenotype in inflamatory bowel disease

21 January 2018

1 reference

12 December 2020

IDO expression by dendritic cells: tolerance and tryptophan catabolism

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12 December 2020

CD4+CD25+ regulatory T cells down-regulate co-stimulatory molecules on antigen-presenting cells

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12 December 2020

A Gly15Arg mutation in the interleukin-10 gene reduces secretion of interleukin-10 in Crohn disease

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12 December 2020

Regulatory role of mature B cells in a murine model of inflammatory bowel disease.

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12 December 2020

Prevention of colitis by interleukin 10-transduced T lymphocytes in the SCID mice transfer model

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12 December 2020

Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

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12 December 2020

X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

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12 December 2020

Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

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12 December 2020

CD40 ligation releases immature dendritic cells from the control of regulatory CD4+CD25+ T cells.

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12 December 2020

Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome

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12 December 2020

Stimulation of CD25(+)CD4(+) regulatory T cells through GITR breaks immunological self-tolerance

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12 December 2020

Neuropilin-1: a surface marker of regulatory T cells

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12 December 2020

Low ileal interleukin 10 concentrations are predictive of endoscopic recurrence in patients with Crohn's disease.

1 reference

12 December 2020

Lymphoproliferative disorders with early lethality in mice deficient in Ctla-4

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12 December 2020

CD25+CD4+ regulatory T cells suppress CD4+ T cell-mediated pulmonary hyperinflammation driven by Pneumocystis carinii in immunodeficient mice

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12 December 2020

IL-10 therapy in Crohn's disease: at the crossroads. Treatment of Crohn's disease with the anti-inflammatory cytokine interleukin 10.

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12 December 2020

The interleukin-10 signal transduction pathway and regulation of gene expression in mononuclear phagocytes.

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12 December 2020

Interactions between commensal intestinal bacteria and the immune system

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12 December 2020

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25(+)CD4(+) regulatory cells that control intestinal inflammation

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12 December 2020

CD4+CD25bright T cells in human intestinal lamina propria as regulatory cells

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12 December 2020

Cutting edge: control of CD8+ T cell activation by CD4+CD25+ immunoregulatory cells

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12 December 2020

A unique subset of self-specific intraintestinal T cells maintains gut integrity

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12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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12 December 2020

Naturally arising CD4+ regulatory t cells for immunologic self-tolerance and negative control of immune responses

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12 December 2020

A rare polyadenylation signal mutation of the FOXP3 gene (AAUAAA-->AAUGAA) leads to the IPEX syndrome

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12 December 2020

Transforming growth factor (TGF)-beta1-producing regulatory T cells induce Smad-mediated interleukin 10 secretion that facilitates coordinated immunoregulatory activity and amelioration of TGF-beta1-mediated fibrosis

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12 December 2020

Cure of innate intestinal immune pathology by CD4+CD25+ regulatory T cells

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12 December 2020

The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

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12 December 2020

A Comparative Study between T Regulatory Type 1 and CD4+CD25+ T Cells in the Control of Inflammation

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12 December 2020

Interleukin-10 and the interleukin-10 receptor

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12 December 2020

A role for NK cells as regulators of CD4+ T cells in a transfer model of colitis

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12 December 2020

Bacteria-triggered CD4(+) T regulatory cells suppress Helicobacter hepaticus-induced colitis

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12 December 2020

In vitro generation of interleukin 10-producing regulatory CD4(+) T cells is induced by immunosuppressive drugs and inhibited by T helper type 1 (Th1)- and Th2-inducing cytokines.

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12 December 2020

Toll-dependent control mechanisms of CD4 T cell activation.

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12 December 2020

CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

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12 December 2020

Origin of regulatory T cells with known specificity for antigen

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12 December 2020

Mesenteric B cells centrally inhibit CD4+ T cell colitis through interaction with regulatory T cell subsets

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12 December 2020

Regulatory T cells and intestinal homeostasis

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12 December 2020

CD25+ CD4+ T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

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12 December 2020

Abrogation of TGFbeta signaling in T cells leads to spontaneous T cell differentiation and autoimmune disease

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12 December 2020

Helicobacter hepaticus triggers colitis in specific-pathogen-free interleukin-10 (IL-10)-deficient mice through an IL-12- and gamma interferon-dependent mechanism

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12 December 2020

CD4+CD25+ Regulatory T Cells Cure Murine Colitis: The Role of IL-10, TGF-β, and CTLA4

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12 December 2020

An essential role for interleukin 10 in the function of regulatory T cells that inhibit intestinal inflammation

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12 December 2020

Lymphoid follicles of the human large bowel mucosa: structure and function

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12 December 2020

Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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12 December 2020

Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease

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12 December 2020

T helper cell 1-type CD4+ T cells, but not B cells, mediate colitis in interleukin 10-deficient mice.

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12 December 2020

Toll-like receptors: balancing host resistance with immune tolerance

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12 December 2020

A Disquisition on Suppressor T Cells

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12 December 2020

Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4

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12 December 2020

Regulatory T cells in the control of immune pathology.

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12 December 2020

Pathogen-specific regulatory T cells provoke a shift in the Th1/Th2 paradigm in immunity to infectious diseases

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12 December 2020

Antigen-dependent proliferation of CD4+ CD25+ regulatory T cells in vivo

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12 December 2020

Suppressive role of B cells in chronic colitis of T cell receptor alpha mutant mice

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12 December 2020

Cloning and characterization of GITR ligand

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12 December 2020

Toll-like receptor-dependent production of IL-12p40 causes chronic enterocolitis in myeloid cell-specific Stat3-deficient mice

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12 December 2020

A unique subpopulation of CD4+ regulatory T cells controls wasting disease, IL-10 secretion and T cell homeostasis

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12 December 2020

Absence of CD4+CD25+ regulatory T cells is associated with a loss of regulation leading to increased pathology in Helicobacter pylori-infected mice

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12 December 2020

T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

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12 December 2020

CD25brightCD4+ regulatory T cells are enriched in inflamed joints of patients with chronic rheumatic disease

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12 December 2020

Generation of regulatory gut-homing human T lymphocytes using ex vivo interleukin 10 gene transfer

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12 December 2020

Type 1 T regulatory cells.

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12 December 2020

The fate of activated T cells migrating through the body: rescue from apoptosis in the tissue of origin

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12 December 2020

Enhanced Th1 activity and development of chronic enterocolitis in mice devoid of Stat3 in macrophages and neutrophils.

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12 December 2020

Homeostasis and anergy of CD4(+)CD25(+) suppressor T cells in vivo

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12 December 2020

Homing of intestinal immune cells.

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12 December 2020

Transforming growth factor-beta in T-cell biology

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12 December 2020

CD4 T cells monospecific to ovalbumin produced by Escherichia coli can induce colitis upon transfer to BALB/c and SCID mice

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12 December 2020

Interleukin-10 inhibits expression of both interferon alpha- and interferon gamma- induced genes by suppressing tyrosine phosphorylation of STAT1

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12 December 2020

CD4+CD25+ immunoregulatory T cells suppress polyclonal T cell activation in vitro by inhibiting interleukin 2 production

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12 December 2020

The inhibitory function of B7 costimulators in T cell responses to foreign and self-antigens

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12 December 2020

Control of intestinal inflammation by regulatory T cells

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12 December 2020

The role of CD4(+)CD25(+) regulatory T cells in Leishmania infection

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12 December 2020

Specificity requirements for selection and effector functions of CD25+4+ regulatory T cells in anti-myelin basic protein T cell receptor transgenic mice.

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12 December 2020

IL-10-producing and naturally occurring CD4+ Tregs: limiting collateral damage

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12 December 2020

CD4(+)CD25(+) T cells facilitate the induction of T cell anergy

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12 December 2020

Cutting edge: self-peptides drive the peripheral expansion of CD4+CD25+ regulatory T cells

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12 December 2020

Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells

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12 December 2020

CD4+CD25+ T(R) cells suppress innate immune pathology through cytokine-dependent mechanisms

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12 December 2020

In vitro generation of IL-10-producing regulatory CD4+ T cells is induced by immunosuppressive drugs and inhibited by Th1- and Th2-inducing cytokines

1 reference

12 December 2020

Over-expression of interleukin 10 in mucosal T cells of patients with active ulcerative colitis

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12 December 2020

Antigen presentation to naive CD4 T cells in the lymph node.

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12 December 2020

CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

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12 December 2020

Mouse glucocorticoid-induced tumor necrosis factor receptor ligand is costimulatory for T cells

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12 December 2020

Enterocolitis and colon cancer in interleukin-10-deficient mice are associated with aberrant cytokine production and CD4(+) TH1-like responses

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12 December 2020

A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis

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12 December 2020

Expression of the integrin alpha Ebeta 7 identifies unique subsets of CD25+ as well as CD25- regulatory T cells

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12 December 2020

Regulatory T cell lineage specification by the forkhead transcription factor foxp3

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12 December 2020

Identification of regulatory T cells in tolerated allografts

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12 December 2020

10.1007/S00281-005-0206-6

Identifiers

DOI

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12 August 2017

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