The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells (Q36171144)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22864381%20AND%20SRC:MED&resulttype=core&format=json

9 February 2020

title

The glucose-deprivation network counteracts lapatinib-induced toxicity in resistant ErbB2-positive breast cancer cells (English)

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9 February 2020

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4

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9 February 2020

Tyler J Moss

5

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9 February 2020

Deepak Nagrath

7

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9 February 2020

Prahlad T. Ram

8

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9 February 2020

author name string

Kakajan Komurov

1

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9 February 2020

Jen-Te Tseng

2

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9 February 2020

Melissa Muller

3

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9 February 2020

Lifeng Yang

6

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9 February 2020

publication date

1 January 2012

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Molecular Systems Biology

9 February 2020

published in

1 reference

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9 February 2020

volume

8

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9 February 2020

page(s)

596

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Defective regulation of autophagy upon leucine deprivation reveals a targetable liability of human melanoma cells in vitro and in vivo.

9 February 2020

cites work

1 reference

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1 October 2017

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Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase

1 October 2017

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Switching addictions between HER2 and FGFR2 in HER2-positive breast tumor cells: FGFR2 as a potential target for salvage after lapatinib failure

1 October 2017

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Hallmarks of Cancer: The Next Generation

1 October 2017

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Autophagy and the integrated stress response

1 October 2017

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Use of data-biased random walks on graphs for the retrieval of context-specific networks from genomic data

1 October 2017

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A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations

1 October 2017

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Endoplasmic reticulum stress and the inflammatory basis of metabolic disease

1 October 2017

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Antioxidant and oncogene rescue of metabolic defects caused by loss of matrix attachment

1 October 2017

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Novel mechanism of lapatinib resistance in HER2-positive breast tumor cells: activation of AXL.

1 October 2017

1 reference

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Glucose deprivation contributes to the development of KRAS pathway mutations in tumor cells

1 October 2017

1 reference

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Understanding the Warburg effect: the metabolic requirements of cell proliferation

1 October 2017

1 reference

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Chemical Genomics Identifies the Unfolded Protein Response as a Target for Selective Cancer Cell Killing during Glucose Deprivation

1 October 2017

1 reference

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MUC1 oncoprotein promotes autophagy in a survival response to glucose deprivation

1 October 2017

1 reference

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Pyrvinium targets the unfolded protein response to hypoglycemia and its anti-tumor activity is enhanced by combination therapy

1 October 2017

1 reference

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Acquired resistance to small molecule ErbB2 tyrosine kinase inhibitors

1 October 2017

1 reference

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Lapatinib: a dual inhibitor of human epidermal growth factor receptor tyrosine kinases

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421441

Survival of cancer cells is maintained by EGFR independent of its kinase activity

1 October 2017

1 reference

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Oncogene addiction: setting the stage for molecularly targeted cancer therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421441

Autophagy is activated in colorectal cancer cells and contributes to the tolerance to nutrient deprivation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3421441

MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

1 October 2017

1 reference

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The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease

1 October 2017

1 reference

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Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias

1 October 2017

1 reference

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

1 October 2017

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EGFR mutation and resistance of non-small-cell lung cancer to gefitinib

1 October 2017

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Reactome: a knowledgebase of biological pathways

1 October 2017

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TSC2 mediates cellular energy response to control cell growth and survival

1 October 2017

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Cancer. Addiction to oncogenes--the Achilles heal of cancer

1 October 2017

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Signaling networks: the origins of cellular multitasking

1 October 2017

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

1 October 2017

1 reference

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Definition of clinically distinct molecular subtypes in estrogen receptor-positive breast carcinomas through genomic grade

1 October 2017

1 reference

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The evolving war on cancer

2 July 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22864381

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MSB.2012.25

1 reference

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9 February 2020

1 reference

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9 February 2020

PubMed publication ID

22864381

1 reference

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