Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality (Q36176643)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17646384%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

title

Deletion of Shp2 in the brain leads to defective proliferation and differentiation in neural stem cells and early postnatal lethality (English)

1 reference

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2 January 2020

1 reference

7

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2 January 2020

Eric E. Zhang

2

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2 January 2020

Ruediger Klein

6

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2 January 2020

author name string

Yuehai Ke

1

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2 January 2020

Kazuki Hagihara

3

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2 January 2020

Dongmei Wu

4

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2 January 2020

Yuhong Pang

5

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2 January 2020

Barbara Ranscht

8

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2 January 2020

Gen-Sheng Feng

9

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2 January 2020

language of work or name

English

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publication date

23 July 2007

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Molecular and Cellular Biology

2 January 2020

published in

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2 January 2020

volume

27

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2 January 2020

issue

19

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2 January 2020

page(s)

6706-6717

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Control of CNS cell-fate decisions by SHP-2 and its dysregulation in Noonan syndrome

2 January 2020

cites work

1 reference

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1 October 2017

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Essential role of Shp2-binding sites on FRS2alpha for corticogenesis and for FGF2-dependent proliferation of neural progenitor cells

1 October 2017

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Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice

1 October 2017

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Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways

1 October 2017

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Bmi1 loss produces an increase in astroglial cells and a decrease in neural stem cell population and proliferation.

1 October 2017

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A positive autoregulatory loop of Jak-STAT signaling controls the onset of astrogliogenesis

1 October 2017

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Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism

1 October 2017

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Bmi-1 dependence distinguishes neural stem cell self-renewal from progenitor proliferation

1 October 2017

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Self-renewal of hematopoietic and leukemic stem cells: a central role for the Polycomb-group gene Bmi-1

1 October 2017

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A definitive role of Shp-2 tyrosine phosphatase in mediating embryonic stem cell differentiation and hematopoiesis

1 October 2017

1 reference

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Bmi-1 is required for maintenance of adult self-renewing haematopoietic stem cells

1 October 2017

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Bmi-1 determines the proliferative capacity of normal and leukaemic stem cells

1 October 2017

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Requirement of Shp-2 tyrosine phosphatase in lymphoid and hematopoietic cell development

1 October 2017

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FGF-2-responsive neural stem cell proliferation requires CCg, a novel autocrine/paracrine cofactor

1 October 2017

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Shp-2 tyrosine phosphatase: signaling one cell or many

1 October 2017

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Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety

1 October 2017

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Cell surface heparan sulfate proteoglycan syndecan-2 induces the maturation of dendritic spines in rat hippocampal neurons

1 October 2017

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Biased suppression of hematopoiesis and multiple developmental defects in chimeric mice containing Shp-2 mutant cells

1 October 2017

1 reference

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Shp-2 has a positive regulatory role in ES cell differentiation and proliferation

1 October 2017

1 reference

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Impaired cerebral cortex development and blood pressure regulation in FGF-2-deficient mice

1 October 2017

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Self-renewal of pluripotent embryonic stem cells is mediated via activation of STAT3

1 October 2017

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Binding of Shp2 tyrosine phosphatase to FRS2 is essential for fibroblast growth factor-induced PC12 cell differentiation

1 October 2017

1 reference

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A deletion mutation in the SH2-N domain of Shp-2 severely suppresses hematopoietic cell development

1 October 2017

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Abnormal mesoderm patterning in mouse embryos mutant for the SH2 tyrosine phosphatase Shp-2.

1 October 2017

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Interaction between NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells is required for optimal response to PDGF.

1 October 2017

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1 October 2017

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2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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2 July 2018

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23 September 2018

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23 September 2018

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Ectopic expression of the bHLH gene Math1 disturbs neural development

23 September 2018

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Regulation of gliogenesis in the central nervous system by the JAK-STAT signaling pathway

23 September 2018

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Multipotential stem cells from the adult mouse brain proliferate and self-renew in response to basic fibroblast growth factor.

23 September 2018

1 reference

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bFGF regulates the proliferative fate of unipotent (neuronal) and bipotent (neuronal/astroglial) EGF-generated CNS progenitor cells

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17646384

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/MCB.01225-07

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17646384%20AND%20SRC:MED&resulttype=core&format=json

2 January 2020

1 reference

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2 January 2020

PubMed publication ID

17646384

1 reference