Cysteine protease inhibitors as chemotherapy: lessons from a parasite target (Q36176812)

12 August 2017

Cysteine protease inhibitors as chemotherapy: lessons from a parasite target (English)

1 reference

12 August 2017

1 reference

P M Selzer

1

1 reference

12 August 2017

S Pingel

2

1 reference

12 August 2017

I Hsieh

3

1 reference

12 August 2017

B Ugele

4

1 reference

12 August 2017

V J Chan

5

1 reference

12 August 2017

J C Engel

6

1 reference

12 August 2017

M Bogyo

7

1 reference

12 August 2017

D G Russell

8

1 reference

12 August 2017

J A Sakanari

9

1 reference

12 August 2017

J H McKerrow

10

1 reference

12 August 2017

language of work or name

English

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publication date

1 September 1999

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

1 reference

12 August 2017

96

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12 August 2017

20

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12 August 2017

11015-11022

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Endocytosis and secretion in trypanosomatid parasites - Tumultuous traffic in a pocket.

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Substrate binding and sequence preference of the proteasome revealed by active-site-directed affinity probes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Leishmania major: molecular modeling of cysteine proteases and prediction of new nonpeptide inhibitors

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Leishmania major: comparison of the cathepsin L- and B-like cysteine protease genes with those of other trypanosomatids

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Evidence from disruption of the lmcpb gene array of Leishmania mexicana that cysteine proteinases are virulence factors.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Structure-based inhibitor design by using protein models for the development of antiparasitic agents

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Immunoelectron microscopy of endosomal trafficking in macrophages infected with microbial pathogens.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Switch of CD4+ T cell differentiation from Th2 to Th1 by treatment with cathepsin B inhibitor in experimental leishmaniasis.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Quantification of cathepsins B and L in cells

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Structure-based design of parasitic protease inhibitors

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Immunoelectron microscopic localization of antigens in malaria parasites.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Inhibition of Leishmania amastigote growth by antipain and leupeptin.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Influence of Ca2+ depletion on cytoskeleton and nucleolus morphology in Trypanosoma brucei

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

The sequence, organization, and expression of the major cysteine protease (cruzain) from Trypanosoma cruzi

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Cysteine protease inhibitors alter Golgi complex ultrastructure and function in Trypanosoma cruzi.

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Cathepsin B-like cysteine proteinase-deficient mutants of Leishmania mexicana.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Impaired Th2 subset development in the absence of CD4.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Peptidyl vinyl sulphones: a new class of potent and selective cysteine protease inhibitors: S2P2 specificity of human cathepsin O2 in comparison with cathepsins S and L.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

The crystal structure of cruzain: a therapeutic target for Chagas' disease

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Vinyl sulfones as mechanism-based cysteine protease inhibitors

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Identification of cell surface carbohydrate and antigenic changes between noninfective and infective developmental stages of Leishmania major promastigotes.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=34234

Application of cryoultramicrotomy to immunocytochemistry

23 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10500116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Leishmania major: analysis of lymphocyte and macrophage cellular phenotypes during infection of susceptible and resistant mice

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10500116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Intracellular trafficking and the parasitophorous vacuole of Leishmania mexicana-infected macrophages

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10500116

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.96.20.11015

1 reference

12 August 2017

0 references

1 reference

12 August 2017

1 reference