Fanconi anemia links reactive oxygen species to insulin resistance and obesity (Q36177982)

12 August 2017

Fanconi anemia links reactive oxygen species to insulin resistance and obesity (English)

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12 August 2017

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reactive oxygen species

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Jie Li

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12 August 2017

Jared Sipple

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12 August 2017

Suzette Maynard

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12 August 2017

Parinda A Mehta

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12 August 2017

Susan R Rose

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12 August 2017

Stella M Davies

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12 August 2017

Qishen Pang

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12 August 2017

25 June 2012

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Antioxidants & Redox Signaling

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12 August 2017

1083-1098

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3423795/fullTextXML

inferred from PubMed Central ID database lookup

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Identification of KIAA1018/FAN1, a DNA repair nuclease recruited to DNA damage by monoubiquitinated FANCD2

1 October 2017

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1 October 2017

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Double-stranded RNA-dependent protein kinase links pathogen sensing with stress and metabolic homeostasis

1 October 2017

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FoxO-mediated defense against oxidative stress in osteoblasts is indispensable for skeletal homeostasis in mice

1 October 2017

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Oxidative stress-specific interaction between FANCD2 and FOXO3a

1 October 2017

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Differential p53 engagement in response to oxidative and oncogenic stresses in Fanconi anemia mice

1 October 2017

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Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes

1 October 2017

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Dissection of the insulin signaling pathway via quantitative phosphoproteomics

1 October 2017

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FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases

1 October 2017

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TNF-alpha induces leukemic clonal evolution ex vivo in Fanconi anemia group C murine stem cells.

1 October 2017

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Endocrine abnormalities in patients with Fanconi anemia

1 October 2017

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Regulation of insulin receptor function

1 October 2017

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Mechanisms linking obesity to insulin resistance and type 2 diabetes

1 October 2017

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Nutrient overload, insulin resistance, and ribosomal protein S6 kinase 1, S6K1.

1 October 2017

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Reactive oxygen species have a causal role in multiple forms of insulin resistance

1 October 2017

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Critical nodes in signalling pathways: insights into insulin action

1 October 2017

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The Fanconi Anemia/BRCA pathway: new faces in the crowd

1 October 2017

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Oxidative stress as a multiple effector in Fanconi anaemia clinical phenotype

1 October 2017

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Protein tyrosine phosphatases and signalling

1 October 2017

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Positive and negative regulation of insulin signaling through IRS-1 phosphorylation

1 October 2017

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The Fanconi anemia proteins functionally interact with the protein kinase regulated by RNA (PKR).

1 October 2017

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Oxidative stress/damage induces multimerization and interaction of Fanconi anemia proteins

1 October 2017

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Insulin signaling through Akt/protein kinase B analyzed by small interfering RNA-mediated gene silencing

1 October 2017

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TNF-alpha and IFN-gamma are overexpressed in the bone marrow of Fanconi anemia patients and TNF-alpha suppresses erythropoiesis in vitro.

1 October 2017

1 reference

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Genetic basis of Fanconi anemia

1 October 2017

1 reference

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A central role for JNK in obesity and insulin resistance

1 October 2017

1 reference

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Oxidants and tyrosine phosphorylation: role of acute and chronic oxidative stress in T-and B-lymphocyte signaling

1 October 2017

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Redox-linked signal transduction pathways for protein tyrosine kinase activation

1 October 2017

1 reference

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Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action

1 October 2017

1 reference

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Fanconi anemia group C protein prevents apoptosis in hematopoietic cells through redox regulation of GSTP1

1 October 2017

1 reference

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Protein-protein interaction in insulin signaling and the molecular mechanisms of insulin resistance

1 October 2017

1 reference

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The transmembrane protein tyrosine phosphatase alpha dephosphorylates the insulin receptor in intact cells

1 October 2017

1 reference

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Role of insulin receptor phosphorylation in the insulinomimetic effects of hydrogen peroxide

1 October 2017

1 reference

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Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain

1 October 2017

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Hydrogen peroxide stimulates tyrosine phosphorylation of focal adhesion kinase in vascular endothelial cells

2 July 2018

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Quercetin protects cutaneous tissue-associated cell types including sensory neurons from oxidative stress induced by glutathione depletion: cooperative effects of ascorbic acid

2 July 2018

1 reference

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Diabetes mellitus in ataxia-telangiectasia, Fanconi anemia, xeroderma pigmentosum, common variable immune deficiency, and severe combined immune deficiency families

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Fanconi anemia proteins and endogenous stresses

2 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Dietary quercetin alleviates diabetic symptoms and reduces streptozotocin-induced disturbance of hepatic gene expression in mice.

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Evaluating the glucose tolerance test in mice

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Abnormalities in glucose tolerance are common in children with fanconi anemia and associated with impaired insulin secretion

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Possible novel therapy for diabetes with cell-permeable JNK-inhibitory peptide

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Redox control of protein tyrosine phosphorylation

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Diabetes Mellitus and the Gene for Fanconi's Anemia

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3423795

Abnormal lymphokine production: a novel feature of the genetic disease Fanconi anemia. II. In vitro and in vivo spontaneous overproduction of tumor necrosis factor alpha

23 September 2018

1 reference

12 December 2020

Tumor necrosis factor-alpha induces hepatic insulin resistance in obese Zucker (fa/fa) rats via interaction of leukocyte antigen-related tyrosine phosphatase with focal adhesion kinase

1 reference

12 December 2020

Role of double-stranded RNA-dependent protein kinase in mediating hypersensitivity of Fanconi anemia complementation group C cells to interferon gamma, tumor necrosis factor-alpha, and double-stranded RNA

1 reference

12 December 2020

Impaired insulin signaling in endothelial cells reduces insulin-induced glucose uptake by skeletal muscle

1 reference

12 December 2020

Identifiers

DOI

10.1089/ARS.2011.4417

1 reference

12 August 2017

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12 August 2017

PubMed publication ID

22482891

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