Targeting glutamine metabolism rescues mice from late-stage cerebral malaria (Q36207221)

12 August 2017

Targeting glutamine metabolism rescues mice from late-stage cerebral malaria (English)

1 reference

12 August 2017

0 references

0 references

Munir Akkaya

5

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Tuan M Tran

object named as

Tuan M Tran

3

0 references

Louis H. Miller

13

object named as

Louis H Miller

1 reference

12 August 2017

15

Susan K Pierce

1 reference

12 August 2017

2

Geoffrey T Hart

1 reference

12 August 2017

4

Michael Waisberg

1 reference

12 August 2017

9

Takele Yazew

1 reference

12 August 2017

1

Emile B Gordon

1 reference

12 August 2017

8

Mirna Pena

1 reference

12 August 2017

Ann S Kim

6

1 reference

12 August 2017

Sara E Hamilton

7

1 reference

12 August 2017

Chen-Feng Qi

10

1 reference

12 August 2017

Chen-Fang Lee

11

1 reference

12 August 2017

Ying-Chun Lo

12

1 reference

12 August 2017

Jonathan D Powell

14

1 reference

12 August 2017

language of work or name

English

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publication date

5 October 2015

1 reference

Proceedings of the National Academy of Sciences of the United States of America

12 August 2017

6

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

12 August 2017

112

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12 August 2017

42

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12 August 2017

13075-13080

1 reference

Inhibiting the Mammalian target of rapamycin blocks the development of experimental cerebral malaria

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Brain swelling and death in children with cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Pathogenic CD8+ T cells in experimental cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Targeting T cell metabolism for therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Early CD8 T-cell memory precursors and terminal effectors exhibit equipotent in vivo degranulation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Real-time imaging reveals the dynamics of leukocyte behaviour during experimental cerebral malaria pathogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Integrating canonical and metabolic signalling programmes in the regulation of T cell responses

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

An atlas of genetic influences on human blood metabolites

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Inflammatory T cell responses rely on amino acid transporter ASCT2 facilitation of glutamine uptake and mTORC1 kinase activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Structural Basis for the Active Site Inhibition Mechanism of Human Kidney-Type Glutaminase (KGA)

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Brain microvessel cross-presentation is a hallmark of experimental cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Metabolic regulation of T lymphocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Protective role of brain water channel AQP4 in murine cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Neuroimmunological blood brain barrier opening in experimental cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Cerebral malaria: we have come a long way

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Acute brain MRI findings in 120 Malawian children with cerebral malaria: new insights into an ancient disease.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

A rapid and robust tri-color flow cytometry assay for monitoring malaria parasite development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Cerebral malaria pathogenesis: revisiting parasite and host contributions.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Testing in mice the hypothesis that melanin is protective in malaria infections

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

The neuropathology of fatal cerebral malaria in malawian children

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Glutamine uptake and metabolism are coordinately regulated by ERK/MAPK during T lymphocyte activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

The antigen-specific CD8+ T cell repertoire in unimmunized mice includes memory phenotype cells bearing markers of homeostatic expansion

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Myelomonocytic cell recruitment causes fatal CNS vascular injury during acute viral meningitis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Experimental models of cerebral malaria

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Statistical significance for genomewide studies

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Clinical features and prognostic indicators in paediatric cerebral malaria: a study of 131 comatose Malawian children.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

In vitro susceptibilities of Plasmodium falciparum to compounds which inhibit nucleotide metabolism

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Computational and experimental analysis identified 6-diazo-5-oxonorleucine as a potential agent for treating infection by Plasmodium falciparum

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Accumulation of Plasmodium berghei-infected red blood cells in the brain is crucial for the development of cerebral malaria in mice

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Differentiating the pathologies of cerebral malaria by postmortem parasite counts

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Blood-brain barrier permeability using tracers and immunohistochemistry.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Perforin-dependent brain-infiltrating cytotoxic CD8+ T lymphocytes mediate experimental cerebral malaria pathogenesis.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

Platelet accumulation in brain microvessels in fatal pediatric cerebral malaria.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4620853

22 September 2018

Identifiers

DOI

10.1073/PNAS.1516544112

1 reference

release_fbo3egop2rgcbkgcrbw7hzpdra

12 August 2017

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/fbo3egop2rgcbkgcrbw7hzpdra

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

12 August 2017

1 reference