Activated protein&#160;C modulates cardiac metabolism and augments autophagy in the ischemic heart (Q36207893)

12 August 2017

Activated protein C modulates cardiac metabolism and augments autophagy in the ischemic heart (English)

1 reference

12 August 2017

0 references

R Costa

1

1 reference

12 August 2017

A Morrison

2

1 reference

12 August 2017

J Wang

3

1 reference

12 August 2017

C Manithody

4

1 reference

12 August 2017

J Li

5

1 reference

12 August 2017

A R Rezaie

6

1 reference

12 August 2017

language of work or name

1 reference

1 September 2012

1 reference

Journal of Thrombosis and Haemostasis

12 August 2017

1 reference

12 August 2017

10

1 reference

12 August 2017

9

1 reference

12 August 2017

1736-1744

1 reference

Mitochondrial DNA that escapes from autophagy causes inflammation and heart failure

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Substrate oxidation and cardiac performance during exercise in disorders of long chain fatty acid oxidation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Role of AMPK-mTOR-Ulk1/2 in the regulation of autophagy: cross talk, shortcuts, and feedbacks

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMP-activated protein kinase: an energy sensor that regulates all aspects of cell function

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

PPAR-γ and AMPK--advantageous targets for myocardial ischemia/reperfusion therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Activated protein C protects against myocardial ischemic/reperfusion injury through AMP-activated protein kinase signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Mapping insulin/GLUT4 circuitry.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Adiponectin (15-36) stimulates steroidogenic acute regulatory (StAR) protein expression and cortisol production in human adrenocortical cells: role of AMPK and MAPK kinase pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Lipid raft redox signaling: molecular mechanisms in health and disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Targeting fatty acid and carbohydrate oxidation--a novel therapeutic intervention in the ischemic and failing heart.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Phosphorylation of ULK1 (hATG1) by AMP-activated protein kinase connects energy sensing to mitophagy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Is autophagy in response to ischemia and reperfusion protective or detrimental for the heart?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Pathogenesis of myocardial ischemia-reperfusion injury and rationale for therapy

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Overnutrition and maternal obesity in sheep pregnancy alter the JNK-IRS-1 signaling cascades and cardiac function in the fetal heart

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMP-activated protein kinase: a core signalling pathway in the heart.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Activated protein C ligation of ApoER2 (LRP8) causes Dab1-dependent signaling in U937 cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The role of autophagy in the heart.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Metabolic remodelling of the failing heart: beneficial or detrimental?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMP-activated protein kinase conducts the ischemic stress response orchestra

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Interaction of cardiovascular risk factors with myocardial ischemia/reperfusion injury, preconditioning, and postconditioning.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The ligand occupancy of endothelial protein C receptor switches the protease-activated receptor 1-dependent signaling specificity of thrombin from a permeability-enhancing to a barrier-protective response in endothelial cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Identification of a specific exosite on activated protein C for interaction with protease-activated receptor 1.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Receptors of the protein C activation and activated protein C signaling pathways are colocalized in lipid rafts of endothelial cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Engineering a disulfide bond to stabilize the calcium-binding loop of activated protein C eliminates its anticoagulant but not its protective signaling properties

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The cytoprotective protein C pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMP-activated protein kinase: a key stress signaling pathway in the heart

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Exosite-dependent regulation of the protein C anticoagulant pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Activation of endothelial cell protease activated receptor 1 by the protein C pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The crystal structure of the endothelial protein C receptor and a bound phospholipid

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Phosphorylation and activation of heart PFK-2 by AMPK has a role in the stimulation of glycolysis during ischaemia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme A thiolase

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

The AMP-activated protein kinase--fuel gauge of the mammalian cell?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Characterization of 5'AMP-activated protein kinase activity in the heart and its role in inhibiting acetyl-CoA carboxylase during reperfusion following ischemia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Translocation of myocardial GLUT-4 and increased glucose uptake through activation of AMPK by AICAR.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3433592

Acute rosiglitazone treatment is cardioprotective against ischemia-reperfusion injury by modulating AMPK, Akt, and JNK signaling in nondiabetic mice.

29 June 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

The alpha2-5'AMP-activated protein kinase is a site 2 glycogen synthase kinase in skeletal muscle and is responsive to glucose loading.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Beneficial effects of trimetazidine in ex vivo working ischemic hearts are due to a stimulation of glucose oxidation secondary to inhibition of long-chain 3-ketoacyl coenzyme a thiolase

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

AMP-activated protein kinase activates p38 mitogen-activated protein kinase by increasing recruitment of p38 MAPK to TAB1 in the ischemic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Activated protein C protects against myocardial ischemia/ reperfusion injury via inhibition of apoptosis and inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Akt activity negatively regulates phosphorylation of AMP-activated protein kinase in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Cytoprotective signaling by activated protein C requires protease-activated receptor-3 in podocytes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Activated protein C utilizes the angiopoietin/Tie2 axis to promote endothelial barrier function.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Bleeding Risk Comparing Targeted Low-Dose Heparin With Bivalirudin in Patients Undergoing Percutaneous Coronary Intervention

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2012.04833.X

Ranolazine stimulates glucose oxidation in normoxic, ischemic, and reperfused ischemic rat hearts

21 January 2018

1 reference

12 December 2020

The endothelial cell protein C receptor. Cell surface expression and direct ligand binding by the soluble receptor

1 reference

12 December 2020

Upregulation of 5'-AMP-activated protein kinase is responsible for the increase in myocardial fatty acid oxidation rates following birth in the newborn rabbit

1 reference

12 December 2020

Measurements of fatty acid and carbohydrate metabolism in the isolated working rat heart

1 reference

12 December 2020

A cardioprotective role for the endothelial protein C receptor in lipopolysaccharide-induced endotoxemia in the mouse

1 reference

12 December 2020

Recombinant human-activated protein C inhibits cardiomyocyte apoptosis in a rat model of myocardial ischemia-reperfusion

1 reference

12 December 2020

Infusion of a biotinylated bis-glucose photolabel: a new method to quantify cell surface GLUT4 in the intact mouse heart

1 reference

12 December 2020

Endothelial protein C receptor polymorphisms and risk of myocardial infarction

1 reference

12 December 2020

10.1111/J.1538-7836.2012.04833.X

Identifiers

DOI

1 reference

12 August 2017

1 reference

12 August 2017

1 reference