The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling (Q36216033)

12 August 2017

The Wnt receptor Ryk plays a role in mammalian planar cell polarity signaling (English)

1 reference

12 August 2017

Maria L Macheda

1

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Neil I Bower

Neil I Bower

5

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Alain Dabdoub

Alain Dabdoub

10

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Benjamin M Hogan

Benjamin M Hogan

4

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Graham J Lieschke

Graham J Lieschke

9

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Steven A Stacker

Steven A Stacker

11

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author name string

Willy W Sun

2

1 reference

12 August 2017

Kumudhini Kugathasan

3

1 reference

12 August 2017

Michael M Halford

6

1 reference

12 August 2017

You Fang Zhang

7

1 reference

12 August 2017

Bonnie E Jacques

8

1 reference

12 August 2017

language of work or name

English

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publication date

6 July 2012

1 reference

Journal of Biological Chemistry

12 August 2017

1 reference

12 August 2017

287

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12 August 2017

35

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12 August 2017

29312-29323

1 reference

Mindbomb 1, an E3 ubiquitin ligase, forms a complex with RYK to activate Wnt/β-catenin signaling

12 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Roles of planar cell polarity pathways in the development of neural [correction of neutral] tube defects

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt5a regulates midbrain dopaminergic axon growth and guidance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Vangl2 promotes Wnt/planar cell polarity-like signaling by antagonizing Dvl1-mediated feedback inhibition in growth cone guidance

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt signaling gradients establish planar cell polarity by inducing Vangl2 phosphorylation through Ror2

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

The Wnt receptor Ryk controls specification of GABAergic neurons versus oligodendrocytes during telencephalon development.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt5b-Ryk pathway provides directional signals to regulate gastrulation movement.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Vang-like protein 2 and Rac1 interact to regulate adherens junctions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt5a induces simultaneous cortical axon outgrowth and repulsive axon guidance through distinct signaling mechanisms

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Sox2 signaling in prosensory domain specification and subsequent hair cell differentiation in the developing cochlea

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Cleavage of the Wnt receptor Ryk regulates neuronal differentiation during cortical neurogenesis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Ryk cooperates with Frizzled 7 to promote Wnt11-mediated endocytosis and is essential for Xenopus laevis convergent extension movements

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Importance of Wnt signaling in the tumor stroma microenvironment.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt5a functions in planar cell polarity regulation in mice

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Frizzled/PCP signalling: a conserved mechanism regulating cell polarity and directed motility

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Convergent extension, planar-cell-polarity signalling and initiation of mouse neural tube closure

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

The Wnt receptor Ryk is required for Wnt5a-mediated axon guidance on the contralateral side of the corpus callosum

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Ryk-mediated Wnt repulsion regulates posterior-directed growth of corticospinal tract

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Regulation of polarized extension and planar cell polarity in the cochlea by the vertebrate PCP pathway

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Fyn/Yes and non-canonical Wnt signalling converge on RhoA in vertebrate gastrulation cell movements

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Mammalian Ryk is a Wnt coreceptor required for stimulation of neurite outgrowth

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Mutation of Celsr1 disrupts planar polarity of inner ear hair cells and causes severe neural tube defects in the mouse

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Identification of Vangl2 and Scrb1 as planar polarity genes in mammals

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Coactivation of Rac and Rho by Wnt/Frizzled signaling is required for vertebrate gastrulation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Shaping the vertebrate body plan by polarized embryonic cell movements

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Morpholino phenocopies of the swirl, snailhouse, somitabun, minifin, silberblick, and pipetail mutations

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Revelations of the RYK receptor

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Ryk-deficient mice exhibit craniofacial defects associated with perturbed Eph receptor crosstalk

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Dishevelled controls cell polarity during Xenopus gastrulation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Silberblick/Wnt11 mediates convergent extension movements during zebrafish gastrulation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Xwnt11 is a target of Xenopus Brachyury: regulation of gastrulation movements via Dishevelled, but not through the canonical Wnt pathway.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Biosynthesis of vascular endothelial growth factor-D involves proteolytic processing which generates non-covalent homodimers

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Molecular cloning and chromosomal localisation of the human homologue of a receptor related to tyrosine kinases (RYK)

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

RYK, a receptor tyrosine kinase-related molecule with unusual kinase domain motifs

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

VANGL1 rare variants associated with neural tube defects affect convergent extension in zebrafish.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

The function of silberblick in the positioning of the eye anlage in the zebrafish embryo

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

Wnt signaling mediates reorientation of outer hair cell stereociliary bundles in the mammalian cochlea.

29 June 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.362681

Wnt-3a-dependent cell motility involves RhoA activation and is specifically regulated by dishevelled-2.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.362681

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1074%2FJBC.M112.362681

Wnt-Ryk signalling mediates medial-lateral retinotectal topographic mapping

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3436188

22 September 2018

Identifiers

DOI

10.1074/JBC.M112.362681

1 reference

12 August 2017

1 reference

12 August 2017

1 reference