The serotonin1A receptor: a representative member of the serotonin receptor family (Q36216404)

12 August 2017

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title

The serotonin1A receptor: a representative member of the serotonin receptor family (English)

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12 August 2017

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Thomas J Pucadyil

1

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12 August 2017

Shanti Kalipatnapu

series ordinal

2

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12 August 2017

Amitabha Chattopadhyay

series ordinal

3

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12 August 2017

publication date

1 June 2005

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Cellular and Molecular Neurobiology

12 August 2017

published in

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12 August 2017

volume

25

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12 August 2017

issue

3-4

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12 August 2017

page(s)

553-580

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Structure and function of proteins in G-protein-coupled signal transfer

12 August 2017

cites work

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https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Centrally acting hypotensive agents with affinity for 5-HT1A binding sites inhibit forskolin-stimulated adenylate cyclase activity in calf hippocampus

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Low serum cholesterol concentration and serotonin metabolism in men.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Biochemical and genetic aspects of 7-dehydrocholesterol reductase and Smith-Lemli-Opitz syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

The discovery of serotonin and its role in neuroscience.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Cholesterol and the cell membrane

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Serum cholesterol concentration and death from suicide in men: Paris prospective study I.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10571-005-3969-3

Fluorescence of protonated excited-state forms of 5-hydroxytryptamine (serotonin) and related indoles

21 January 2018

1 reference

12 December 2020

Distribution and cellular localization of mRNA coding for 5-HT1A receptor in the rat brain: correlation with receptor binding.

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12 December 2020

Activation of G-protein-coupled receptors: a common molecular mechanism

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12 December 2020

Serotonin1A receptor acts during development to establish normal anxiety-like behaviour in the adult

1 reference

12 December 2020

Antagonism of 5-hydroxytryptamine1A (5-HT1A) receptor-mediated modulation of adenylate cyclase activity by pindolol and propranolol isomers

1 reference

12 December 2020

Cholesterol organization in membranes at low concentrations: effects of curvature stress and membrane thickness

1 reference

12 December 2020

4-(2'-Methoxy-phenyl)-1-[2'-(n-2"-pyridinyl)-p-iodobenzamido]-ethyl- piperazine ([125I]p-MPPI) as a new selective radioligand of serotonin-1A sites in rat brain: in vitro binding and autoradiographic studies

1 reference

12 December 2020

In vivo binding of [123I]4-(2'-methoxyphenyl)-1-[2'-(N-2"-pyridinyl)- p-iodobenzamido-]ethyl-piperazine, p-MPPI, to 5-HT1A receptors in rat brain

1 reference

12 December 2020

Serotonin receptor 1A knockout: an animal model of anxiety-related disorder

1 reference

12 December 2020

Identification of enteramine, the specific hormone of the enterochromaffin cell system, as 5-hydroxytryptamine.

1 reference

12 December 2020

G protein specificity in receptor-effector coupling. Analysis of the roles of G0 and Gi2 in GH4C1 pituitary cells

1 reference

12 December 2020

Heptahelical receptor signaling: beyond the G protein paradigm.

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12 December 2020

Molecular manipulations as tools for enhancing our understanding of 5-HT neurotransmission

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12 December 2020

G-Protein coupled receptors: models, mutagenesis, and drug design

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12 December 2020

A serotonin receptor gene (5HT1A) variant found in a Tourette's syndrome patient.

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12 December 2020

5-HT system and cognition

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12 December 2020

Neuronal instability: implications for Rett's syndrome.

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12 December 2020

A role for the serotonin system in the mechanism of action of antidepressant treatments: preclinical evidence.

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12 December 2020

Serotonin upregulates the activity of phagocytosis through 5-HT1A receptors

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12 December 2020

Serotonin, serotonin 5-HT(1A) receptors and dopamine in blood peripheral lymphocytes of major depression patients

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12 December 2020

Fluorescence characteristics of 5-hydroxytryptamine (serotonin)

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12 December 2020

Lipid-protein interactions in biological membranes: a structural perspective

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12 December 2020

Statins and the risk of dementia

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12 December 2020

Sequence alignment of the G-protein coupled receptor superfamily

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12 December 2020

Solubilization and functional reconstitution of biomembrane components

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12 December 2020

Solubilization of high affinity G-protein-coupled serotonin1A receptors from bovine hippocampus using pre-micellar CHAPS at low concentration

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12 December 2020

Inflammatory mediators of asthma: an update

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12 December 2020

5-HT receptors linked to adenylyl cyclase activity in mammalian brain

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12 December 2020

Fluorescence techniques for studying protein structure.

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12 December 2020

Differential properties of pre- and postsynaptic 5-hydroxytryptamine1A receptors in the dorsal raphe and hippocampus: I. Effect of spiperone.

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12 December 2020

Multiple phosphorylation sites are required for pathway-selective uncoupling of the 5-hydroxytryptamine1A receptor by protein kinase C

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12 December 2020

Molecular, pharmacological and functional diversity of 5-HT receptors

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12 December 2020

5-HT(1A) receptor mutant mice exhibit enhanced tonic, stress-induced and fluoxetine-induced serotonergic neurotransmission

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12 December 2020

Genomic organization, coding sequence and functional expression of human 5-HT2 and 5-HT1A receptor genes

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12 December 2020

Increased vulnerability to cocaine in mice lacking the serotonin-1B receptor

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12 December 2020

Serotonin 5-HT1 receptors mediate inhibition of cyclic AMP production in neurons

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12 December 2020

A conserved threonine residue in the second intracellular loop of the 5-hydroxytryptamine 1A receptor directs signaling specificity.

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12 December 2020

Serotonin2C receptors and serotonin2C receptor-mediated phosphoinositide hydrolysis in the brain of alcohol-preferring and alcohol-nonpreferring rats.

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12 December 2020

Piperazine derivatives including the putative anxiolytic drugs, buspirone and ipsapirone, are agonists at 5-HT1A receptors negatively coupled with adenylate cyclase in hippocampal neurons

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12 December 2020

Agonist-independent activation of Gz by the 5-hydroxytryptamine1A receptor co-expressed in Spodoptera frugiperda cells. Distinguishing inverse agonists from neutral antagonists

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12 December 2020

Increased anxiety of mice lacking the serotonin1A receptor

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12 December 2020

Forces and factors that contribute to the structural stability of membrane proteins

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12 December 2020

Identification of presynaptic serotonin autoreceptors using a new ligand: 3H-PAT

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12 December 2020

Characterization of recombinant human serotonin 5HT1A receptors expressed in Chinese hamster ovary cells. [3H]spiperone discriminates between the G-protein-coupled and -uncoupled forms

1 reference

12 December 2020

Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture

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12 December 2020

Role of extracellular disulfide-bonded cysteines in the ligand binding function of the beta 2-adrenergic receptor

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12 December 2020

Photophysics of a neurotransmitter: ionization and spectroscopic properties of serotonin

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12 December 2020

Malformation syndromes due to inborn errors of cholesterol synthesis

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12 December 2020

Serotonin content of some mammalian tissues and urine and a method for its determination

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12 December 2020

The developmental role of serotonin: news from mouse molecular genetics

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12 December 2020

Cholesterol is required for Leishmania donovani infection: implications in leishmaniasis

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12 December 2020

Cellular localization of the 5-HT1A receptor in primate brain neurons and glial cells

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12 December 2020

Increased membrane cholesterol reduces the potentiation of GABA(A) currents by neurosteroids in dissociated hippocampal neurones

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12 December 2020

Alterations in detergent solubility of heterotrimeric G proteins after chronic activation of G(i/o)-coupled receptors: changes in detergent solubility are in correlation with onset of adenylyl cyclase superactivation

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12 December 2020

Acceleration of the effect of selected antidepressant drugs in major depression by 5-HT1A antagonists.

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12 December 2020

Differential solubilization of lipids along with membrane proteins by different classes of detergents

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12 December 2020

Pertussis toxin blocks 5-HT1A and GABAB receptor-mediated inhibition of serotonergic neurons

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12 December 2020

Identification of two serine residues involved in agonist activation of the beta-adrenergic receptor

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12 December 2020

Serum vasoconstrictor, serotonin; isolation and characterization

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12 December 2020

Effect of alcohols on G-protein coupling of serotonin(1A) receptors from bovine hippocampus

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12 December 2020

Local anesthetic inhibition of G protein-coupled receptor signaling by interference with Galpha(q) protein function

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12 December 2020

Of mice and flies: commonalities among 5-HT receptors

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12 December 2020

The molecular evolution of G protein-coupled receptors: focus on 5-hydroxytryptamine receptors

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12 December 2020

Induction of the serotonin1A receptor in neuronal cells during prolonged stress and degeneration

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12 December 2020

Defect of receptor-G protein coupling in human gallbladder with cholesterol stones

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12 December 2020

The 5-Hydroxytryptamine(1A) Receptor Is Stably Palmitoylated, and Acylation Is Critical for Communication of Receptor with Gi Protein

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12 December 2020

Detergents as tools in membrane biochemistry

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12 December 2020

Production of specific anti-rat 5-HT1A receptor antibodies in rabbits injected with a synthetic peptide.

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12 December 2020

Cholesterol metabolism in the brain

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12 December 2020

Sorting of GPI-anchored proteins to glycolipid-enriched membrane subdomains during transport to the apical cell surface

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12 December 2020

Solubilization of serotonin1A receptors heterologously expressed in Chinese hamster ovary cells

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12 December 2020

Attenuated 5-HT1A receptor signaling in brains of suicide victims: involvement of adenylyl cyclase, phosphatidylinositol 3-kinase, Akt and mitogen-activated protein kinase

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12 December 2020

Modulation of antagonist binding to serotonin1A receptors from bovine hippocampus by metal ions

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12 December 2020

Interaction of serotonin1A receptors from bovine hippocampus with tertiary amine local anesthetics

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12 December 2020

Receptors coupling to G proteins: is there a signal behind the sequence?

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12 December 2020

Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin1A receptors from bovine hippocampus

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12 December 2020

The GTP-insensitive component of high-affinity [3H]8-hydroxy-2-(di-n-propylamino)tetralin binding in the rat hippocampus corresponds to an oxidized state of the 5-hydroxytryptamine1A receptor.

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12 December 2020

The recombinant 5-HT1A receptor: G protein coupling and signalling pathways.

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12 December 2020

8-Hydroxy-2-(di-n-propylamino)tetralin, a new centrally acting 5-hydroxytryptamine receptor agonist

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12 December 2020

Blockade of 5-HT1A receptors compensates loss of hippocampal cholinergic neurotransmission involved in working memory of rats.

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12 December 2020

Detection of the 5-HT1A receptor and 5-HT1A receptor mRNA in the rat bowel and pancreas: comparison with 5-HT1P receptors

1 reference

12 December 2020

Elevated anxiety and antidepressant-like responses in serotonin 5-HT1A receptor mutant mice

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12 December 2020

[3H]8-hydroxy-2-(di-n-propylamino)tetralin binding to pre- and postsynaptic 5-hydroxytryptamine sites in various regions of the rat brain.

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12 December 2020

Immunocytochemical localization of serotonin1A receptors in the rat central nervous system

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12 December 2020

A review of central 5-HT receptors and their function

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12 December 2020

Seven-transmembrane receptors

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12 December 2020

Functional expression of the human serotonin 5-HT1A receptor in Escherichia coli. Ligand binding properties and interaction with recombinant G protein alpha-subunits

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12 December 2020

How cells handle cholesterol.

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12 December 2020

The state of lipid rafts: from model membranes to cells

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12 December 2020

Measuring serotonin distribution in live cells with three-photon excitation

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12 December 2020

Inhibition of tryptophan hydroxylase activity and decreased 5-HT1A receptor binding in a mouse model of Huntington's disease

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12 December 2020

Reconstitution of receptors and GTP-binding regulatory proteins (G proteins) in Sf9 cells. A direct evaluation of selectivity in receptor.G protein coupling

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12 December 2020

The role of conserved aspartate and serine residues in ligand binding and in function of the 5-HT1A receptor: a site-directed mutation study

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12 December 2020

Temperature-dependent interaction of the bovine hippocampal serotonin(1A) receptor with G-proteins

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12 December 2020

Mg2+ enhances high affinity [3H]8-hydroxy-2-(di-n-propylamino) tetralin binding and guanine nucleotide modulation of serotonin-1a receptors.

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12 December 2020

Differential addressing of 5-HT1A and 5-HT1B receptors in epithelial cells and neurons

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12 December 2020

Modulation of agonist and antagonist interactions in serotonin 1A receptors by alcohols

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12 December 2020

Metal ion and guanine nucleotide modulations of agonist interaction in G-protein-coupled serotonin1A receptors from bovine hippocampus

1 reference

12 December 2020

Impaired Repression at a 5-Hydroxytryptamine 1A Receptor Gene Polymorphism Associated with Major Depression and Suicide

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12 December 2020

Functional rafts in cell membranes

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12 December 2020

Differential discrimination of G-protein coupling of serotonin(1A) receptors from bovine hippocampus by an agonist and an antagonist

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12 December 2020

Cloning, functional expression, and mRNA tissue distribution of the rat 5-hydroxytryptamine1A receptor gene

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12 December 2020

Spectrophotofluorometric assay in the visible and ultraviolet

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12 December 2020

Raft membrane domains: from a liquid-ordered membrane phase to a site of pathogen attack

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12 December 2020

Regulation of receptor function by cholesterol.

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12 December 2020

Membrane organization at low cholesterol concentrations: a study using 7-nitrobenz-2-oxa-1,3-diazol-4-yl-labeled cholesterol.

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12 December 2020

The distribution of 5-HT1A and 5-HT2A receptor mRNA in human brain.

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12 December 2020

Heterologous expression of the serotonin 5-HT1A receptor in neural and non-neural cell lines

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12 December 2020

The organizing potential of sphingolipids in intracellular membrane transport

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12 December 2020

Somatodendritic localization of 5-HT1A and preterminal axonal localization of 5-HT1B serotonin receptors in adult rat brain

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12 December 2020

Human 5-HT1A receptor expressed in insect cells activates endogenous G(o)-like G protein(s).

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12 December 2020

5-Hydroxytryptamine1A receptor synthetic peptides. Mechanisms of adenylyl cyclase inhibition.

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12 December 2020

Identification of residues important for ligand binding to the human 5-hydroxytryptamine1A serotonin receptor.

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12 December 2020

Comparative anatomical distribution of 5-HT1A receptor mRNA and 5-HT1A binding in rat brain — a combined in situ hybridisation/in vitro receptor autoradiographic study

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12 December 2020

A quantitative analysis of beta-adrenergic receptor interactions: resolution of high and low affinity states of the receptor by computer modeling of ligand binding data

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12 December 2020

Reduction of in vivo striatal 5-hydroxytryptamine release by 8-OH-DPAT after inactivation of Gi/G(o) proteins in dorsal raphe nucleus

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12 December 2020

Dual couplings of the cloned 5-HT1A receptor to both adenylyl cyclase and phospholipase C is mediated via the same Gi protein

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12 December 2020

Genomic organization of adrenergic and serotonin receptors in the mouse: Linkage mapping of sequence-related genes provides a method for examining mammalian chromosome evolution

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12 December 2020

An aspartate conserved among G-protein receptors confers allosteric regulation of alpha 2-adrenergic receptors by sodium

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12 December 2020

Serotonin1A receptors are increased in postmortem prefrontal cortex in schizophrenia.

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12 December 2020

Decreased prevalence of Alzheimer disease associated with 3-hydroxy-3-methyglutaryl coenzyme A reductase inhibitors.

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12 December 2020

S 14506: novel receptor coupling at 5-HT(1A) receptors.

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12 December 2020

Characterization of the 5-hydroxytryptamine1a receptor-mediated inhibition of forskolin-stimulated adenylate cyclase activity in guinea pig and rat hippocampal membranes

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12 December 2020

Serotonin decreases population spike amplitude in hippocampal cells through a pertussis toxin substrate

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12 December 2020

CCK receptor dysfunction in muscle membranes from human gallbladders with cholesterol stones

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12 December 2020

Ligand binding characteristics of the human serotonin1A receptor heterologously expressed in CHO cells.

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12 December 2020

Uncovering molecular mechanisms involved in activation of G protein-coupled receptors

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12 December 2020

Pharmacology of 5-hydroxytryptamine-1A receptors which inhibit cAMP production in hippocampal and cortical neurons in primary culture.

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12 December 2020

Early localization of mRNA coding for 5-HT1A receptors in human brain during development

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12 December 2020

Regulation of mu-opioid receptor in neural cells by extracellular sodium

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12 December 2020

A Putative alpha-helical Gbetagamma-coupling Domain in the Second Intracellular Loop of the 5-HT1A Receptora

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12 December 2020

Expression of the human 5-hydroxytryptamine1A receptor in Sf9 cells. Reconstitution of a coupled phenotype by co-expression of mammalian G protein subunits

1 reference

12 December 2020

Lipid rafts and signal transduction

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12 December 2020

A potential 5-HT1A receptor antagonist: p-MPPI.

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12 December 2020

Lipid sorting in epithelial cells

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12 December 2020

The genomic clone G-21 which resembles a beta-adrenergic receptor sequence encodes the 5-HT1A receptor

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12 December 2020

5-Hydroxytryptamine receptors

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12 December 2020

Cholesterol modulates ligand binding and G-protein coupling to serotonin(1A) receptors from bovine hippocampus.

1 reference

12 December 2020

Use of detergents to study membrane rafts: the good, the bad, and the ugly

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12 December 2020

Structure and function of the brain serotonin system

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12 December 2020

Exploring detergent insolubility in bovine hippocampal membranes: a critical assessment of the requirement for cholesterol

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12 December 2020

Dissecting the role of the serotonin system in neuropsychiatric disorders using knockout mice

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12 December 2020

Selective activation of inhibitory G-protein alpha-subunits by partial agonists of the human 5-HT1A receptor

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12 December 2020

Impaired hippocampal-dependent learning and functional abnormalities in the hippocampus in mice lacking serotonin(1A) receptors.

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12 December 2020

Recent advances in brain cholesterol dynamics: transport, domains, and Alzheimer's disease

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12 December 2020

Effects of novel 5-HT1A receptor antagonists on measures of post-synaptic 5-HT1A receptor activation in vivo

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12 December 2020

The C-terminus of Gi family G-proteins as a determinant of 5-HT(1A) receptor coupling

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12 December 2020

The G-protein nanomachine

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12 December 2020

Statin effects on cholesterol micro-domains in brain plasma membranes

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12 December 2020

Differential addressing of 5-HT1A and 5-HT1B receptors in transfected LLC-PK1 epithelial cells: a model of receptor targeting in neurons

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12 December 2020

Cholesterol in mood and anxiety disorders: review of the literature and new hypotheses

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12 December 2020

A hypothesis linking intracellular sodium, membrane receptors, and hypertension

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12 December 2020

5-HT1A receptor activates Na+/H+ exchange in CHO-K1 cells through Gialpha2 and Gialpha3.

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12 December 2020

Arrangement of rhodopsin transmembrane α-helices

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12 December 2020

Identification of a single amino acid residue responsible for the binding of a class of beta-adrenergic receptor antagonists to 5-hydroxytryptamine1A receptors

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12 December 2020

A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor

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12 December 2020

The cloning and sequence analysis of the rat serotonin-1A receptor gene

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12 December 2020

5-Hydroxytryptamine-interacting drugs in animal models of anxiety disorders: more than 30 years of research.

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12 December 2020

Elevated alcohol consumption in null mutant mice lacking 5-HT1B serotonin receptors.

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12 December 2020

How receptors talk to trimeric G proteins

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12 December 2020

G protein-coupled receptor allosterism and complexing

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12 December 2020

Protein and lipid sorting from thetrans–Golgi network to the plasma membrane in polarized cells

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12 December 2020

Dependence of critical micelle concentration of a zwitterionic detergent on ionic strength: implications in receptor solubilization.

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12 December 2020

Cloning and differentiation-induced expression of a murine serotonin1A receptor in a septal cell line

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12 December 2020

Cell-specific physical and functional coupling of human 5-HT1A receptors to inhibitory G protein alpha-subunits and lack of coupling to Gs alpha

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12 December 2020

Distribution of serotonin receptors.

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12 December 2020

Intracellular cholesterol transport and compartmentation

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12 December 2020

(S)-N-tert-butyl-3-(4-(2-methoxyphenyl)-piperazin-1-yl)-2-phenylpropanamide [(S)-WAY-100135]: a selective antagonist at presynaptic and postsynaptic 5-HT1A receptors

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12 December 2020

Endocytic sorting of lipid analogues differing solely in the chemistry of their hydrophobic tails.

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12 December 2020

An intronless gene encoding a potential member of the family of receptors coupled to guanine nucleotide regulatory proteins

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12 December 2020

Lipid rafts: elusive or illusive?

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12 December 2020

Evidence that G(z)-proteins couple to hypothalamic 5-HT(1A) receptors in vivo.

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12 December 2020

Role of 5-HT in stress, anxiety, and depression.

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12 December 2020

Site-directed mutagenesis of beta-adrenergic receptors. Identification of conserved cysteine residues that independently affect ligand binding and receptor activation.

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12 December 2020

Immunohistochemical mapping of cellular and subcellular distribution of 5-HT1A receptors in rat and human kidneys

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12 December 2020

Instability of the G-protein beta5 subunit in detergent

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12 December 2020

Neurotransmitter imaging in living cells based on native fluorescence detection

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12 December 2020

G protein-coupled receptors as direct targets of inhaled anesthetics

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12 December 2020

Protein-induced formation of cholesterol-rich domains

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12 December 2020

A mutation-induced activated state of the beta 2-adrenergic receptor. Extending the ternary complex model

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12 December 2020

A critical review of brain cholesterol metabolism

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12 December 2020

Multiplicity of mechanisms of serotonin receptor signal transduction

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12 December 2020

A novel role for serotonin in heart

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12 December 2020

Preferential utilization of newly synthesized cholesterol for brain growth in neonatal lambs.

1 reference

12 December 2020

10.1007/S10571-005-3969-3

Identifiers

DOI

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12 August 2017

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