PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice (Q36218704)

12 August 2017

PTEN deletion enhances survival, neurite outgrowth and function of dopamine neuron grafts to MitoPark mice (English)

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12 August 2017

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YaJun Zhang

1

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12 August 2017

Ann-Charlotte Granholm

2

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12 August 2017

Kyounghee Huh

3

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12 August 2017

Lufei Shan

4

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12 August 2017

Oscar Diaz-Ruiz

5

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12 August 2017

Nasir Malik

6

1 reference

12 August 2017

Lars Olson

7

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12 August 2017

Barry J Hoffer

8

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12 August 2017

Carl R Lupica

9

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12 August 2017

Alexander F Hoffman

10

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12 August 2017

Cristina M Bäckman

11

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12 August 2017

language of work or name

English

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publication date

1 September 2012

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12 August 2017

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12 August 2017

135

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12 August 2017

Pt 9

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12 August 2017

2736-2749

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describes a project that uses

12 August 2017

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3437026/fullTextXML

inferred from PubMed Central ID database lookup

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The MitoPark Mouse - an animal model of Parkinson's disease with impaired respiratory chain function in dopamine neurons.

1 October 2017

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PTEN/mTOR and axon regeneration.

1 October 2017

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MitoPark mice mirror the slow progression of key symptoms and L-DOPA response in Parkinson's disease

1 October 2017

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Selective deletion of PTEN in dopamine neurons leads to trophic effects and adaptation of striatal medium spiny projecting neurons

1 October 2017

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Involvement of Akt in neurite outgrowth

1 October 2017

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Promoting axon regeneration in the adult CNS by modulation of the PTEN/mTOR pathway

1 October 2017

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Nerve injury signaling

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Transgenic rodent models of Parkinson’s disease

1 October 2017

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Recovery of functional deficits following early donor age ventral mesencephalic grafts in a rat model of Parkinson's disease.

1 October 2017

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Phosphatase PTEN in neuronal injury and brain disorders

1 October 2017

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Improved survival of young donor age dopamine grafts in a rat model of Parkinson's disease.

1 October 2017

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Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons

1 October 2017

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Increased fiber outgrowth from xeno-transplanted human embryonic dopaminergic neurons with co-implants of polymer-encapsulated genetically modified cells releasing glial cell line-derived neurotrophic factor

1 October 2017

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1 October 2017

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Transcription-dependent and -independent control of neuronal survival by the PI3K-Akt signaling pathway

1 October 2017

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Transplantation of embryonic dopamine neurons for severe Parkinson's disease

1 October 2017

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Real-time dynamics of dopamine released from neuronal transplants in experimental Parkinson's disease

1 October 2017

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Implantation of bioactive growth factor-secreting rods enhances fetal dopaminergic graft survival, outgrowth density, and functional recovery in a rat model of Parkinson's disease.

1 October 2017

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Enhancement of survival of stored dopaminergic cells and promotion of graft survival by exposure of human fetal nigral tissue to glial cell line--derived neurotrophic factor in patients with Parkinson's disease. Report of two cases and technical con

1 October 2017

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Cellular survival: a play in three Akts

1 October 2017

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Akt promotes cell survival by phosphorylating and inhibiting a Forkhead transcription factor

1 October 2017

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Problems with long-term levodopa therapy for Parkinson's disease

1 October 2017

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Grafts of fetal dopamine neurons survive and improve motor function in Parkinson's disease

1 October 2017

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Dopaminergic pathway reconstruction by Akt/Rheb-induced axon regeneration

1 October 2017

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Akt suppresses retrograde degeneration of dopaminergic axons by inhibition of macroautophagy

29 June 2018

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Lazaroid-enhanced survival of grafted dopamine neurons does not increase target innervation.

29 June 2018

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A complex program of striatal gene expression induced by dopaminergic stimulation.

29 June 2018

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Human fetal dopamine neurons grafted into the striatum in two patients with severe Parkinson's disease. A detailed account of methodology and a 6-month follow-up

29 June 2018

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An assessment of the validity of densitometric measures of striatal tyrosine hydroxylase-positive fibers: relationship to apomorphine-induced rotations in 6-hydroxydopamine lesioned rats.

29 June 2018

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Survival of implanted fetal dopamine cells and neurologic improvement 12 to 46 months after transplantation for Parkinson's disease

29 June 2018

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Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models.

29 June 2018

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22 September 2018

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Effects of GDNF pretreatment on function and survival of transplanted fetal ventral mesencephalic cells in the 6-OHDA rat model of Parkinson's disease.

22 September 2018

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Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus.

22 September 2018

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D1 dopamine receptor supersensitivity in the dopamine-depleted striatum results from a switch in the regulation of ERK1/2/MAP kinase.

22 September 2018

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22 September 2018

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Long-term changes of striatal dopamine D2 receptors in patients with Parkinson's disease: a study with positron emission tomography and [11C]raclopride.

22 September 2018

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Evidence for long-term survival and function of dopaminergic grafts in progressive Parkinson's disease.

22 September 2018

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Tiny steps towards an HIV vaccine

22 September 2018

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Chapter 83 Neural transplantation in Parkinson's disease: the Swedish experience

21 January 2018

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FETAL DOPAMINE-RICH MESENCEPHALIC GRAFTS IN PARKINSON'S DISEASE

21 January 2018

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Fetal dopamine-rich mesencephalic grafts in Parkinson's disease

21 January 2018

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Positron emission tomography demonstrates dopamine D2 receptor supersensitivity in the striatum of patients with early Parkinson's disease

21 October 2018

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12 December 2020

Neural transplantation in Parkinson's disease: the Swedish experience

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12 December 2020

Akt/protein kinase B prevents injury-induced motoneuron death and accelerates axonal regeneration

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12 December 2020

Delayed recovery of movement-related cortical function in Parkinson's disease after striatal dopaminergic grafts

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12 December 2020

Pharmacodynamic interactions between phenytoin and valproate: individual and combined antiepileptic and neurotoxic actions in mice.

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5 June 2022

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Identifiers

DOI

10.1093/BRAIN/AWS196

1 reference

12 August 2017

1 reference

12 August 2017

1 reference