Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations (Q36220721)

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6 February 2020

title

Stem and progenitor cells in myelodysplastic syndromes show aberrant stage-specific expansion and harbor genetic and epigenetic alterations (English)

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6 February 2020

10

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Andrea Pellagatti

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Jacqueline Boultwood

16

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Alan F List

22

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Jaroslaw P. Maciejewski

19

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Jaroslaw Maciejewski

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Tushar D Bhagat

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Ulrich Steidl

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Christine McMahon

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John M Greally

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Carolina Schinke

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Sanchari Bhattacharyya

9

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Sanchari Bhattacharyya

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Cristina Montagna

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13

Samir Parekh

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23

Christian Steidl

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6

Roni Tamari

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11

Christoph Heuck

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author name string

Britta Will

1

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Li Zhou

2

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Thomas O Vogler

3

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Susanna Ben-Neriah

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Yiting Yu

7

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Yonkai Mo

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Lewis Silverman

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B Hilda Ye

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Amit Verma

25

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6 February 2020

language of work or name

English

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publication date

2 July 2012

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6 February 2020

number of pages

11

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inferred from page(s)

published in

Blood

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6 February 2020

volume

120

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6 February 2020

issue

10

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6 February 2020

page(s)

2076-2086

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STAT3 inhibition is a therapeutic strategy for ABC-like diffuse large B-cell lymphoma

6 February 2020

cites work

1 reference

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Coalesced multicentric analysis of 2,351 patients with myelodysplastic syndromes indicates an underestimation of poor-risk cytogenetics of myelodysplastic syndromes in the international prognostic scoring system

1 October 2017

1 reference

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Stat3 signaling in acute myeloid leukemia: ligand-dependent and -independent activation and induction of apoptosis by a novel small-molecule Stat3 inhibitor

1 October 2017

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Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells

1 October 2017

1 reference

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DNA methyltransferase 1 is essential for and uniquely regulates hematopoietic stem and progenitor cells

1 October 2017

1 reference

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Effect of the nonpeptide thrombopoietin receptor agonist Eltrombopag on bone marrow cells from patients with acute myeloid leukemia and myelodysplastic syndrome

1 October 2017

1 reference

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MDS and secondary AML display unique patterns and abundance of aberrant DNA methylation

1 October 2017

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High-resolution genome-wide cytosine methylation profiling with simultaneous copy number analysis and optimization for limited cell numbers.

1 October 2017

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Efficacy of azacitidine compared with that of conventional care regimens in the treatment of higher-risk myelodysplastic syndromes: a randomised, open-label, phase III study

1 October 2017

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Aberrant DNA methylation is a dominant mechanism in MDS progression to AML.

1 October 2017

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Inhibition of the TGF-beta receptor I kinase promotes hematopoiesis in MDS.

1 October 2017

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1 October 2017

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A distal single nucleotide polymorphism alters long-range regulation of the PU.1 gene in acute myeloid leukemia.

1 October 2017

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Selective chemical probe inhibitor of Stat3, identified through structure-based virtual screening, induces antitumor activity

1 October 2017

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Stattic: a small-molecule inhibitor of STAT3 activation and dimerization

1 October 2017

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Inhibition of overactivated p38 MAPK can restore hematopoiesis in myelodysplastic syndrome progenitors.

1 October 2017

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Transformation from committed progenitor to leukaemia stem cell initiated by MLL-AF9.

1 October 2017

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Comparative isoschizomer profiling of cytosine methylation: the HELP assay

1 October 2017

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The JAK2 V617F mutation occurs in hematopoietic stem cells in polycythemia vera and predisposes toward erythroid differentiation

1 October 2017

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Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML

1 October 2017

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STAT3 deletion during hematopoiesis causes Crohn's disease-like pathogenesis and lethality: a critical role of STAT3 in innate immunity

1 October 2017

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1 October 2017

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Identifiers

DOI

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