NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila. (Q36228869)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940169%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

title

NF-kappaB translocation prevents host cell death after low-dose challenge by Legionella pneumophila (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940169%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

main subject

NF-κB

0 references

Legionella pneumophila

1 reference

1 reference

1

1 reference

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29 December 2019

2

Ralph R Isberg

1 reference

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29 December 2019

language of work or name

English

0 references

publication date

28 August 2006

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940169%20AND%20SRC:MED&resulttype=core&format=json

Journal of Experimental Medicine

29 December 2019

published in

1 reference

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29 December 2019

volume

203

1 reference

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29 December 2019

page(s)

2177-2189

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29 December 2019

issue

9

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Cytosolic recognition of flagellin by mouse macrophages restricts Legionella pneumophila infection

29 December 2019

cites work

1 reference

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Flagellin-deficient Legionella mutants evade caspase-1- and Naip5-mediated macrophage immunity

1 October 2017

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Recognition of cytosolic DNA activates an IRF3-dependent innate immune response

1 October 2017

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1 October 2017

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Signaling pathways and genes that inhibit pathogen-induced macrophage apoptosis--CREB and NF-kappaB as key regulators

1 October 2017

1 reference

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Inhibition of MAPK and NF-kappa B pathways is necessary for rapid apoptosis in macrophages infected with Yersinia

1 October 2017

1 reference

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A yeast genetic system for the identification and characterization of substrate proteins transferred into host cells by the Legionella pneumophila Dot/Icm system

1 October 2017

1 reference

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Insights into host responses against pathogens from transcriptional profiling.

1 October 2017

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Pathogen effector protein screening in yeast identifies Legionella factors that interfere with membrane trafficking

1 October 2017

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Reactive oxygen species promote TNFalpha-induced death and sustained JNK activation by inhibiting MAP kinase phosphatases

1 October 2017

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A20 inhibits NF-kappaB activation by dual ubiquitin-editing functions

1 October 2017

1 reference

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Syntaxin 6 and Vti1b form a novel SNARE complex, which is up-regulated in activated macrophages to facilitate exocytosis of tumor necrosis Factor-alpha.

1 October 2017

1 reference

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Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island

1 October 2017

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The role of Toll-like receptors and Nod proteins in bacterial infection

1 October 2017

1 reference

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A specific gene expression program triggered by Gram-positive bacteria in the cytosol

1 October 2017

1 reference

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"The stress of dying": the role of heat shock proteins in the regulation of apoptosis

1 October 2017

1 reference

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Multiple substrates of the Legionella pneumophila Dot/Icm system identified by interbacterial protein transfer.

1 October 2017

1 reference

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A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Role of Toll-like receptor signaling in the apoptotic response of macrophages to Yersinia infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Cag pathogenicity island-specific responses of gastric epithelial cells to Helicobacter pylori infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

A bacterial guanine nucleotide exchange factor activates ARF on Legionella phagosomes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Legionella pneumophila suppresses interleukin-12 production by macrophages

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Nuclear factor-kappa B activation and innate immune response in microbial pathogen infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Salmonella typhimurium infection and lipopolysaccharide stimulation induce similar changes in macrophage gene expression.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Intracellular growth of Legionella pneumophila in Dictyostelium discoideum, a system for genetic analysis of host-pathogen interactions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

The prosurvival Bcl-2 homolog Bfl-1/A1 is a direct transcriptional target of NF-kappaB that blocks TNFalpha-induced apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

IAP family proteins--suppressors of apoptosis

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Apoptosis in macrophages and alveolar epithelial cells during early stages of infection by Legionella pneumophila and its role in cytopathogenicity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Expression of Legionella pneumophila virulence traits in response to growth conditions

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Legionella pneumophila DotA protein is required for early phagosome trafficking decisions that occur within minutes of bacterial uptake

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Host cell killing and bacterial conjugation require overlapping sets of genes within a 22-kb region of the Legionella pneumophila genome.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

IRAK (Pelle) family member IRAK-2 and MyD88 as proximal mediators of IL-1 signaling

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Topology of Legionella pneumophila DotA: an inner membrane protein required for replication in macrophages

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

The molecular ecology of legionellae

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Association of Legionella pneumophila with the macrophage endoplasmic reticulum

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

The Legionnaires' disease bacterium (Legionella pneumophila) inhibits phagosome-lysosome fusion in human monocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Formation of a novel phagosome by the Legionnaires' disease bacterium (Legionella pneumophila) in human monocytes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Purification of Legionella pneumophila major outer membrane protein and demonstration that it is a porin

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Charcoal-yeast extract agar: primary isolation medium for Legionella pneumophila

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Legionnaires' disease: description of an epidemic of pneumonia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Incomplete activation of macrophage apoptosis during intracellular replication of Legionella pneumophila.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Activation of NF-kappaB by Toxoplasma gondii correlates with increased expression of antiapoptotic genes and localization of phosphorylated IkappaB to the parasitophorous vacuole membrane

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

The role of nuclear factor-kappa B in cytokine gene regulation

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

LidA, a translocated substrate of the Legionella pneumophila type IV secretion system, interferes with the early secretory pathway

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Intracellular multiplication of Legionella pneumophila depends on host cell amino acid transporter SLC1A5.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

The Legionella IcmS-IcmW protein complex is important for Dot/Icm-mediated protein translocation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Legionella reveal dendritic cell functions that facilitate selection of antigens for MHC class II presentation.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

How the parasitic bacterium Legionella pneumophila modifies its phagosome and transforms it into rough ER: implications for conversion of plasma membrane to the ER membrane

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Evidence for pore-forming ability by Legionella pneumophila

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Conjugative transfer by the virulence system of Legionella pneumophila.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2118400

Two distinct defects in intracellular growth complemented by a single genetic locus in Legionella pneumophila

22 September 2018

1 reference

12 December 2020

Murine macrophages differentially produce proinflammatory cytokines after infection with virulent vs. avirulent Legionella pneumophila

1 reference

12 December 2020

Identification of Icm protein complexes that play distinct roles in the biogenesis of an organelle permissive for Legionella pneumophila intracellular growth

1 reference

12 December 2020

Bcl-2 family member Bfl-1/A1 sequesters truncated bid to inhibit is collaboration with pro-apoptotic Bak or Bax

1 reference

12 December 2020

Lipopolysaccharides from Legionella and Rhizobium stimulate mouse bone marrow granulocytes via Toll-like receptor 2

1 reference

12 December 2020

The Legionella pneumophila LidA protein: a translocated substrate of the Dot/Icm system associated with maintenance of bacterial integrity

1 reference

12 December 2020

Dictyostelium transcriptional host cell response upon infection with Legionella

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20060766

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940169%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16940169%20AND%20SRC:MED&resulttype=core&format=json

29 December 2019

1 reference