Platelets in atherothrombosis: lessons from mouse models (Q36230859)

12 August 2017

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title

Platelets in atherothrombosis: lessons from mouse models (English)

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12 August 2017

Nieswandt B

1

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12 August 2017

Aktas B

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2

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12 August 2017

Moers A

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3

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12 August 2017

Sachs UJ

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4

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12 August 2017

1 August 2005

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Journal of Thrombosis and Haemostasis

12 August 2017

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12 August 2017

3

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12 August 2017

8

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12 August 2017

1725-1736

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Platelets in atherothrombosis

12 August 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Rat model of arterial thrombosis induced by ferric chloride

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Photochemically induced endothelial injury in the mouse as a screening model for inhibitors of vascular intimal thickening.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A crucial role of glycoprotein VI for platelet recruitment to the injured arterial wall in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A critical role of platelet adhesion in the initiation of atherosclerotic lesion formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Anti-glycoprotein VI treatment severely compromises hemostasis in mice with reduced alpha2beta1 levels or concomitant aspirin therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Generation and rescue of a murine model of platelet dysfunction: the Bernard-Soulier syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Genetic deletion of mouse platelet glycoprotein Ibbeta produces a Bernard-Soulier phenotype with increased alpha-granule size

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Amelioration of the macrothrombocytopenia associated with the murine Bernard-Soulier syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Absence of GPIbalpha is responsible for aberrant membrane development during megakaryocyte maturation: ultrastructural study using a transgenic model

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Increased thrombin responsiveness in platelets from mice lacking glycoprotein V

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Increased thrombogenesis and embolus formation in mice lacking glycoprotein V

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Von Willebrand's disease.

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A mouse model of severe von Willebrand disease: defects in hemostasis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Plasma fibronectin promotes thrombus growth and stability in injured arterioles

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Platelet-collagen interaction: is GPVI the central receptor?

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Anti-GPVI-associated ITP: an acquired platelet disorder caused by autoantibody-mediated clearance of the GPVI/FcRgamma-chain complex from the human platelet surface.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Long-term antithrombotic protection by in vivo depletion of platelet glycoprotein VI in mice

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Glycoprotein VI but not alpha2beta1 integrin is essential for platelet interaction with collagen

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

The contribution of glycoprotein VI to stable platelet adhesion and thrombus formation illustrated by targeted gene deletion

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Involvement of glycoprotein VI in platelet thrombus formation on both collagen and von Willebrand factor surfaces under flow conditions

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Integrin alpha2beta1 mediates outside-in regulation of platelet spreading on collagen through activation of Src kinases and PLCgamma2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Integrin α2-Deficient Mice Develop Normally, Are Fertile, but Display Partially Defective Platelet Interaction with Collagen

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

The alpha(2) integrin subunit-deficient mouse: a multifaceted phenotype including defects of branching morphogenesis and hemostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Multiple integrin-ligand interactions synergize in shear-resistant platelet adhesion at sites of arterial injury in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

The contributions of the alpha 2 beta 1 integrin to vascular thrombosis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Syk tyrosine kinase required for mouse viability and B-cell development

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A PLC gamma 2-independent platelet collagen aggregation requiring functional association of GPVI and integrin alpha2beta1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

The role of heterotrimeric G proteins in platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Decreased platelet aggregation, increased bleeding time and resistance to thromboembolism in P2Y1-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Lineage-specific overexpression of the P2Y1 receptor induces platelet hyper-reactivity in transgenic mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Identification of the platelet ADP receptor targeted by antithrombotic drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Role of the thrombin receptor in development and evidence for a second receptor.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Protease-activated receptor 3 is a second thrombin receptor in humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Cloning and characterization of human protease-activated receptor 4

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A dual thrombin receptor system for platelet activation

21 January 2018

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https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

PAR3 is a cofactor for PAR4 activation by thrombin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Protection against thrombosis in mice lacking PAR3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Role of thrombin signalling in platelets in haemostasis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Loss of signaling through the G protein, Gz, results in abnormal platelet activation and altered responses to psychoactive drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Defective platelet activation in G alpha(q)-deficient mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Activation of G12/G13 results in shape change and Rho/Rho-kinase-mediated myosin light chain phosphorylation in mouse platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

G13 is an essential mediator of platelet activation in hemostasis and thrombosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Unresponsiveness of platelets lacking both Galpha(q) and Galpha(13). Implications for collagen-induced platelet activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Coordinated signaling through both G12/13 and G(i) pathways is sufficient to activate GPIIb/IIIa in human platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Coactivation of two different G protein-coupled receptors is essential for ADP-induced platelet aggregation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Signaling through Gi family members in platelets. Redundancy and specificity in the regulation of adenylyl cyclase and other effectors

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

CalDAG-GEFI integrates signaling for platelet aggregation and thrombus formation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Relationships between Rap1b, affinity modulation of integrin alpha IIbbeta 3, and the actin cytoskeleton

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Integrins: dynamic scaffolds for adhesion and signaling in platelets

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Integrin cytoplasmic tyrosine motif is required for outside-in alphaIIbbeta3 signalling and platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Plasma fibronectin supports neuronal survival and reduces brain injury following transient focal cerebral ischemia but is not essential for skin-wound healing and hemostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Soluble CD40 ligand induces β 3 integrin tyrosine phosphorylation and triggers platelet activation by outside-in signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Signaling by ephrinB1 and Eph kinases in platelets promotes Rap1 activation, platelet adhesion, and aggregation via effector pathways that do not require phosphorylation of ephrinB1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Deficiency or inhibition of Gas6 causes platelet dysfunction and protects mice against thrombosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Mer receptor tyrosine kinase signaling participates in platelet function

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Role of Gas6 receptors in platelet signaling during thrombus stabilization and implications for antithrombotic therapy

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Accumulation of tissue factor into developing thrombi in vivo is dependent upon microparticle P-selectin glycoprotein ligand 1 and platelet P-selectin

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Localized reduction of atherosclerosis in von Willebrand factor-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Circulating activated platelets exacerbate atherosclerosis in mice deficient in apolipoprotein E.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Roles of thromboxane A(2) and prostacyclin in the development of atherosclerosis in apoE-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Beta3 integrin deficiency promotes atherosclerosis and pulmonary inflammation in high-fat-fed, hyperlipidemic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

Requirement for CD154 in the progression of atherosclerosis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1538-7836.2005.01488.X

10.1111/J.1538-7836.2005.01488.X

21 January 2018

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DOI

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12 August 2017

1 reference