A new era for Type 2 diabetes genetics (Q36237867)

13 August 2017

4 references

13 March 2019

14 March 2019

24 March 2019

4 February 2021

A new era for Type 2 diabetes genetics (English)

1 reference

13 August 2017

2 references

4 February 2021

1

1 reference

13 August 2017

26 September 2007

1 reference

PMCID

2121132

13 August 2017

1 November 2007

4 references

13 March 2019

14 March 2019

24 March 2019

4 February 2021

5 references

13 August 2017

13 March 2019

14 March 2019

24 March 2019

4 February 2021

24

1 reference

13 August 2017

1181-1186

1 reference

13 August 2017

11

1 reference

Common variants of the novel type 2 diabetes genes CDKAL1 and HHEX/IDE are associated with decreased pancreatic beta-cell function

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Variation in FTO contributes to childhood obesity and severe adult obesity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A common allele on chromosome 9 associated with coronary heart disease

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A common variant on chromosome 9p21 affects the risk of myocardial infarction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Replication of genome-wide association signals in UK samples reveals risk loci for type 2 diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A variant in CDKAL1 influences insulin response and risk of type 2 diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A genome-wide association study identifies novel risk loci for type 2 diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

TCF7L2: the biggest story in diabetes genetics since HLA?

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Functional variation and evolution of non-coding DNA.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Combining information from common type 2 diabetes risk polymorphisms improves disease prediction

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

p16INK4a induces an age-dependent decline in islet regenerative potential

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Inhibition of cyclin-dependent kinase 5 activity protects pancreatic beta cells from glucotoxicity

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A haplotype map of the human genome

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Cdk5-dependent regulation of glucose-stimulated insulin secretion.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Polymorphisms in the insulin-degrading enzyme gene are associated with type 2 diabetes in men from the NHLBI Framingham Heart Study

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

The common PPARgamma Pro12Ala polymorphism is associated with decreased risk of type 2 diabetes

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Loss of Cdk4 expression causes insulin-deficient diabetes and Cdk4 activation results in beta-islet cell hyperplasia

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

Large-scale association studies of variants in genes encoding the pancreatic beta-cell KATP channel subunits Kir6.2 (KCNJ11) and SUR1 (ABCC8) confirm that the KCNJ11 E23K variant is associated with type 2 diabetes

1 October 2017

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

MicroRNAs: 'ribo-regulators' of glucose homeostasis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Evaluating coverage of genome-wide association studies

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Evaluating and improving power in whole-genome association studies using fixed marker sets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Association and haplotype analysis of the insulin-degrading enzyme (IDE) gene, a strong positional and biological candidate for type 2 diabetes susceptibility

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Characterization of the abnormal pancreatic development, reduced growth and infertility in Cdk4 mutant mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Pancreatic islets from cyclin-dependent kinase 4/R24C (Cdk4) knockin mice have significantly increased beta cell mass and are physiologically functional, indicating that Cdk4 is a potential target for pancreatic beta cell mass regeneration in Type 1

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

Hypoplasia of endocrine and exocrine pancreas in homozygous transgenic TGF-beta1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1464-5491.2007.02274.X

High-density haplotype structure and association testing of the insulin-degrading enzyme (IDE) gene with type 2 diabetes in 4,206 people

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2121132

10.1111/J.1464-5491.2007.02274.X

22 September 2018

Identifiers

DOI

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

2121132