Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants (Q36243575)

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English	Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants	scientific article

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scholarly article

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Vitamin E protects against lipid peroxidation and rescues tumorigenic phenotypes in cowden/cowden-like patient-derived lymphoblast cells with germline SDHx variants (English)

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

1 reference

based on heuristic

inferred from title

2

object named as

Charis Eng

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

author name string

Ying Ni

1

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

language of work or name

0 references

publication date

24 July 2012

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Clinical Cancer Research

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

18

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

4954-4961

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

Lifetime cancer risks in individuals with germline PTEN mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Germline SDHx variants modify breast and thyroid cancer risks in Cowden and Cowden-like syndrome via FAD/NAD-dependant destabilization of p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

A clinical scoring system for selection of patients for PTEN mutation testing is proposed on the basis of a prospective study of 3042 probands

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Germline epigenetic regulation of KILLIN in Cowden and Cowden-like syndrome

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Naturally occurring germline and tumor-associated mutations within the ATP-binding motifs of PTEN lead to oxidative damage of DNA associated with decreased nuclear p53.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Tocopherol transfer protein sensitizes prostate cancer cells to vitamin E.

1 reference

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1 October 2017

Effect of selenium and vitamin E on risk of prostate cancer and other cancers: the Selenium and Vitamin E Cancer Prevention Trial (SELECT)

1 reference

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The p53-p66shc-Manganese Superoxide Dismutase (MnSOD) network: a mitochondrial intrigue to generate reactive oxygen species.

1 reference

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1 October 2017

Germline mutations and variants in the succinate dehydrogenase genes in Cowden and Cowden-like syndromes

1 reference

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Alpha-tocopheryl succinate induces apoptosis by targeting ubiquinone-binding sites in mitochondrial respiratory complex II.

1 reference

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Txnip balances metabolic and growth signaling via PTEN disulfide reduction

1 reference

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Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism

1 reference

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1 October 2017

Mitochondrial mutations in cancer

1 reference

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1 October 2017

Distinct clinical features of paraganglioma syndromes associated with SDHB and SDHD gene mutations

1 reference

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1 October 2017

On respiratory impairment in cancer cells

1 reference

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A role for mitochondrial enzymes in inherited neoplasia and beyond

1 reference

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Mitochondrial defects in cancer

1 reference

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1 October 2017

The major lipid peroxidation product, trans-4-hydroxy-2-nonenal, preferentially forms DNA adducts at codon 249 of human p53 gene, a unique mutational hotspot in hepatocellular carcinoma

1 reference

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1 October 2017

Lipid peroxidation: a novel and unifying concept of the etiology of renal cell carcinoma (United States).

1 reference

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1 October 2017

Germ-line mutations in nonsyndromic pheochromocytoma

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Will the real Cowden syndrome please stand up: revised diagnostic criteria

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

1 reference

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1 October 2017

Duplex DNA catalyzes the chemical rearrangement of a malondialdehyde deoxyguanosine adduct

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Lipid peroxidation-DNA damage by malondialdehyde

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Germline PTEN mutations in Cowden syndrome-like families.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Persistent oxidative stress in cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Production of large amounts of hydrogen peroxide by human tumor cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

1 October 2017

Oxidative stress in malignant melanoma and non-melanoma skin cancer

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

29 June 2018

Mitochondrial superoxide radical formation is controlled by electron bifurcation to the high and low potential pathways

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22 September 2018

Effect of mitochondrial electron transport chain inhibitors on superoxide radical generation in rat hippocampal and striatal slices

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3445717

22 September 2018

PTEN blocks insulin-mediated ETS-2 phosphorylation through MAP kinase, independently of the phosphoinositide 3-kinase pathway

1 reference

https://pubmed.ncbi.nlm.nih.gov/22829200

12 December 2020

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4-Hydroxynonenal formation during ischemia and reperfusion of rat small intestine

1 reference

https://pubmed.ncbi.nlm.nih.gov/22829200

12 December 2020

based on heuristic

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Vitamin E Analogues Inhibit Angiogenesis by Selective Induction of Apoptosis in Proliferating Endothelial Cells: The Role of Oxidative Stress

1 reference

https://pubmed.ncbi.nlm.nih.gov/22829200

12 December 2020

based on heuristic

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Identifiers

10.1158/1078-0432.CCR-12-1055

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PMC publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

PubMed publication ID

1 reference

Europe PubMed Central

PMC publication ID

13 August 2017

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