Mitochondrial mutations in cancer (Q36557971)

14 August 2017

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title

Mitochondrial mutations in cancer (English)

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14 August 2017

Brandon M

1

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14 August 2017

Baldi P

series ordinal

2

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14 August 2017

Wallace DC

series ordinal

3

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14 August 2017

language of work or name

English

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publication date

1 August 2006

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14 August 2017

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14 August 2017

25

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14 August 2017

4647-4662

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14 August 2017

34

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https://scigraph.springernature.com/pub.10.1038/sj.onc.1209607

14 August 2017

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cites work

Detection of somatic mutations in the mitochondrial DNA control region of colorectal and gastric tumors by heteroduplex and single-strand conformation analysis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

The akt kinase: molecular determinants of oncogenicity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA mutations in normal and tumor tissues from breast cancer patients

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

On the InterAktion between hexokinase and the mitochondrion.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mutation of a nuclear succinate dehydrogenase gene results in mitochondrial respiratory chain deficiency

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

MITOMAP: a human mitochondrial genome database--2004 update

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A tandem duplication in the D-loop of human mitochondrial DNA is associated with deletions in mitochondrial myopathies

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

mtDNA haplogroup X: An ancient link between Europe/Western Asia and North America?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Expression of genes from the human active and inactive X chromosomes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Novel mtDNA mutations and oxidative phosphorylation dysfunction in Russian LHON families

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA sequences of primates: Tempo and mode of evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

High aerobic glycolysis of rat hepatoma cells in culture: Role of mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA and human evolution

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA G10398A polymorphism and invasive breast cancer in African-American women

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Simultaneous generation of multiple mitochondrial DNA mutations in human prostate tumors suggests mitochondrial hyper-mutagenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Homology and structural relationships between the dimeric and monomeric circular forms of mitochondrial DNA from human leukemic leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA alterations in cancer.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Going APE over ref-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Discovery of a major D-loop replication origin reveals two modes of human mtDNA synthesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Facile detection of mitochondrial DNA mutations in tumors and bodily fluids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Why do cancers have high aerobic glycolysis?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Inhibition of early apoptotic events by Akt/PKB is dependent on the first committed step of glycolysis and mitochondrial hexokinase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial gene mutation, but not large-scale deletion, is a feature of colorectal carcinomas with mitochondrial microsatellite instability

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial proteome: altered cytochrome c oxidase subunit levels in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Novel mitochondrial DNA deletion found in a renal cell carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial genome variation and the origin of modern humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A mutation in succinate dehydrogenase cytochrome b causes oxidative stress and ageing in nematodes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial mutations in early stage prostate cancer and bodily fluids

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Radiation of human mitochondria DNA types analyzed by restriction endonuclease cleavage patterns

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Redox regulation of the DNA repair function of the human AP endonuclease Ape1/ref-1.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A common mitochondrial DNA variant associated with susceptibility to dilated cardiomyopathy in two different populations

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

High frequency of mitochondrial DNA mutations in glioblastoma multiforme identified by direct sequence comparison to blood samples

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial proteome: cancer-altered metabolism associated with cytochrome c oxidase subunit level variation

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Gene expression and tumor cell escape from host effector mechanisms in murine large cell lymphoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Somatic mutations in the D-loop and decrease in the copy number of mitochondrial DNA in human hepatocellular carcinoma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Biallelic inactivation of fumarate hydratase (FH) occurs in nonsyndromic uterine leiomyomas but is rare in other tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA variant 16189T>C is associated with susceptibility to endometrial cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Hexokinase-mitochondria interaction mediated by Akt is required to inhibit apoptosis in the presence or absence of Bax and Bak

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Akt inhibits apoptosis downstream of BID cleavage via a glucose-dependent mechanism involving mitochondrial hexokinases

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

The mtDNA T8993G (NARP) mutation results in an impairment of oxidative phosphorylation that can be improved by antioxidants

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA somatic mutations (point mutations and large deletions) and mitochondrial DNA variants in human thyroid pathology: a study with emphasis on Hürthle cell tumors

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

The evolution of free radicals and oxidative stress

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

The structure of human mitochondrial DNA variation.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Natural selection shaped regional mtDNA variation in humans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mutations in SDHC cause autosomal dominant paraganglioma, type 3.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial bound type II hexokinase: a key player in the growth and survival of many cancers and an ideal prospect for therapeutic intervention

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

mtDNA mutations increase tumorigenicity in prostate cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Somatic mutations of the mitochondrial genome in human colorectal tumours

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Does a common mitochondrial DNA polymorphism underlie susceptibility to diabetes and the thrifty genotype?

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A common mitochondrial DNA variant is associated with insulin resistance in adult life.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Effects of purifying and adaptive selection on regional variation in human mtDNA.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Extension of murine life span by overexpression of catalase targeted to mitochondria

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A defect in the cytochrome b large subunit in complex II causes both superoxide anion overproduction and abnormal energy metabolism in Caenorhabditis elegans

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Tumor-associated mutations of rat mitochondrial transfer RNA genes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

AKT plays a central role in tumorigenesis

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA alterations in thyroid cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Premature ageing in mice expressing defective mitochondrial DNA polymerase

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Cytoplasmic transfer of the mtDNA nt 8993 T-->G (ATP6) point mutation associated with Leigh syndrome into mtDNA-less cells demonstrates cosegregation with a decrease in state III respiration and ADP/O ratio

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Assessment of mitochondrial oxidative phosphorylation in patient muscle biopsies, lymphoblasts, and transmitochondrial cell lines

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Early-onset renal cell carcinoma as a novel extraparaganglial component of SDHB-associated heritable paraganglioma

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA variation in human evolution and disease

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

mtDNA variation, climatic adaptation, degenerative diseases, and longevity

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA control region sequence variation in migraine headache and cyclic vomiting syndrome.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Muscle-specific mutations accumulate with aging in critical human mtDNA control sites for replication

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

On the Origin of Cancer Cells

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Mitochondrial DNA mutations and mitochondrial DNA depletion in gastric cancer

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Ribozymes targeting serine/threonine kinase Akt1 sensitize cells to anticancer drugs

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Somatic mitochondrial DNA (mtDNA) mutations in papillary thyroid carcinomas and differential mtDNA sequence variants in cases with thyroid tumours.

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Strikingly higher frequency in centenarians and twins of mtDNA mutation causing remodeling of replication origin in leukocytes

1 reference

https://api.crossref.org/works/10.1038%2FSJ.ONC.1209607

7 January 2021

Identifiers

DOI

10.1038/SJ.ONC.1209607

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Dimensions Publication ID

14 August 2017

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1 reference