Cytochromes P-450 in rats: structures, functions, properties and relevant human forms (Q36255451)

13 August 2017

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title

Cytochromes P-450 in rats: structures, functions, properties and relevant human forms (English)

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13 August 2017

Soucek P

1

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13 August 2017

Gut I

series ordinal

2

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13 August 2017

language of work or name

English

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publication date

1 January 1992

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13 August 2017

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13 August 2017

volume

22

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13 August 2017

issue

1

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13 August 2017

page(s)

83-103

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Mutagen activation by cDNA-expressed P(1)450, P(3)450, and P450a

13 August 2017

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Isolation and characterization of cDNA clones for cytochromes P-450 immunochemically related to rat hepatic P-450 form PB-1.

21 January 2018

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Primary structure of a cytochrome P-450: coding nucleotide sequence of phenobarbital-inducible cytochrome P-450 cDNA from rat liver

21 January 2018

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Characterization of cDNAs, mRNAs, and proteins related to human liver microsomal cytochrome P-450 (S)-mephenytoin 4'-hydroxylase

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Molecular genetics of the P-450 superfamily

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Evolution of the P450 gene superfamily: animal-plant 'warfare', molecular drive and human genetic differences in drug oxidation

21 January 2018

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Pregnenolone 16 alpha-carbonitrile-inducible P-450 gene family: gene conversion and differential regulation

21 January 2018

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Debrisoquine 4-hydroxylase: characterization of a new P450 gene subfamily, regulation, chromosomal mapping, and molecular analysis of the DA rat polymorphism

21 January 2018

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Human P450PCN1: sequence, chromosome localization, and direct evidence through cDNA expression that P450PCN1 is nifedipine oxidase

21 January 2018

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Characterization of the common genetic defect in humans deficient in debrisoquine metabolism

21 January 2018

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DNA-expressed human cytochrome P450s: a new age of molecular toxicology and human risk assessment

21 January 2018

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Characterization of human microsomal cytochrome P-450 enzymes

21 January 2018

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Hydrodynamic characterization of highly purified and functionally active liver microsomal cytochrome P-450

21 January 2018

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Purification and characterization of microsomal cytochrome P-450s

21 January 2018

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Aflatoxin B1 hydroxylation by the pregnenolone-16 alpha-carbonitrile-inducible form of rat liver microsomal cytochrome P-450.

21 January 2018

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Aromatase cytochrome P450 in rat ovarian granulosa cells before and after luteinization: adenosine 3',5'-monophosphate-dependent and independent regulation. Cloning and sequencing of rat aromatase cDNA and 5' genomic DNA.

21 January 2018

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Complete nucleotide sequence of two steroid 21-hydroxylase genes tandemly arranged in human chromosome: a pseudogene and a genuine gene

21 January 2018

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Four species of cDNAs for cytochrome P450 isozymes immunorelated to P450C-M/F encode for members of P450IID subfamily, increasing the number of members within the subfamily

21 January 2018

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Human P1-450 gene sequence and correlation of mRNA with genetic differences in benzo[a]pyrene metabolism

21 January 2018

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Human P3(450): cDNA and complete amino acid sequence

21 January 2018

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Sexual dimorphism in the control of growth hormone secretion

21 January 2018

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Metabolic activation of mutagenic heterocyclic aromatic amines from protein pyrolysates

21 January 2018

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Coding nucleotide sequence of 3-methylcholanthrene-inducible cytochrome P-450d cDNA from rat liver

21 January 2018

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Structure and drug inducibility of the human cytochrome P-450c gene

21 January 2018

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Identification of genetically high risk individuals to lung cancer by DNA polymorphisms of the cytochrome P45 0IA1 gene

21 January 2018

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Activation and inactivation of a variety of mutagenic compounds by the reconstituted system containing highly purified preparations of cytochrome P-450 from rat liver.

21 January 2018

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cDNA and amino acid sequences of two members of the human P450IIC gene subfamily

21 January 2018

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The rat clofibrate-inducible CYP4A gene subfamily. I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization, and identification of a conserved 19-bp upstream element

21 January 2018

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The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes

21 January 2018

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Identification of a novel P450 expressed in rat lung: cDNA cloning and sequence, chromosome mapping, and induction by 3-methylcholanthrene

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498259209053106

Isolation of a new human fetal liver cytochrome P450 cDNA clone: evidence for expression of a limited number of forms of cytochrome P450 in human fetal livers

21 January 2018

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https://api.crossref.org/works/10.3109%2F00498259209053106

Molecular cloning and sequence analysis of cDNA containing the entire coding region for human fetal liver cytochrome P-450

21 January 2018

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A Constitutive Member of the Rat Cytochrome P450IIB Subfamily: Full-Length Coding Sequence of the P450IIB3 cDNA

21 January 2018

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The structure of cDNA clones encoding the aromatase P-450 isolated from a rat Leydig cell tumor line demonstrates differential processing of aromatase mRNA in rat ovary and a neoplastic cell line

21 January 2018

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The role of highly purified cytochrome P-450 isozymes in the activation of 4-aminobiphenyl to mutagenic products in the Ames test.

21 January 2018

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Molecular cloning and expression of cDNAS encoding rat aldosterone synthase: variants of cytochrome P-450(11 beta)

21 January 2018

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The CYP2D gene subfamily: analysis of the molecular basis of the debrisoquine 4-hydroxylase deficiency in DA rats

21 January 2018

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Characterization of a cDNA for rat P-450g, a highly polymorphic, male-specific cytochrome in the P-450IIC subfamily

21 January 2018

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A novel human cytochrome P450 gene (P450IIB): chromosomal localization and evidence for alternative splicing

21 January 2018

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Complete cDNA sequence of a cytochrome P-450 inducible by glucocorticoids in human liver

21 January 2018

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Rat testis P-450(17)alpha cDNA: the deduced amino acid sequence, expression and secondary structural configuration

21 January 2018

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The P450 gene superfamily: recommended nomenclature.

21 January 2018

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The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Identification of a new P450 expressed in human lung: complete cDNA sequence, cDNA-directed expression, and chromosome mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

The human CYP2F gene subfamily: identification of a cDNA encoding a new cytochrome P450, cDNA-directed expression, and chromosome mapping

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Molecular cloning of cDNA for cholesterol 7 alpha-hydroxylase from rat liver microsomes. Nucleotide sequence and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Molecular cloning and sequence analysis of cDNA encoding human cholesterol 7 alpha-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Activation mechanisms to chemical toxicity

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Metabolic activation of carcinogens and toxic chemicals.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Human cytochrome P-450 4 mRNA and gene: part of a multigene family that contains Alu sequences in its mRNA

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Specificity of rat liver cytochrome P-450 isozymes in the mutagenic activation of benzo[a]pyrene, aromatic amines and aflatoxin B1

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Purification and characterization of hepatic microsomal cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Physiological and pathophysiological alterations in rat hepatic cytochrome P-450.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Characterization of a cDNA encoding a new member of the glucocorticoid-responsive cytochromes P450 in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Cytochrome P-450-mediated activation of procarcinogens and promutagens to DNA-damaging products by measuring expression of umu gene in Salmonella typhimurium TA1535/pSK1002.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Metabolic activation of environmental carcinogens and mutagens by human liver microsomes. Role of cytochrome P-450 homologous to a 3-methylcholanthrene-inducible isozyme in rat liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Genotoxic and mutagenic activation of aflatoxin B1 by constitutive forms of cytochrome P-450 in rat liver microsomes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Sequencing of cDNA inserts encoding aromatase cytochrome P-450 (P-450AROM).

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Selective mutagenic activation by cytochrome P3-450 of carcinogenic arylamines found in foods.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Distinct organization of methylcholanthrene- and phenobarbital-inducible cytochrome P-450 genes in the rat

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Cloning and characterization of a novel member of the cytochrome P450 subfamily IVA in rat prostate

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

A cDNA encoding a rat mitochondrial cytochrome P450 catalyzing both the 26-hydroxylation of cholesterol and 25-hydroxylation of vitamin D3: gonadotropic regulation of the cognate mRNA in ovaries

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Regulation of cytochrome P-450j, a high-affinity N-nitrosodimethylamine demethylase, in rat hepatic microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Cloning and sequence determination of a complementary DNA related to human liver microsomal cytochrome P-450 S-mephenytoin 4-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Molecular cloning of cDNA for vitamin D3 25-hydroxylase from rat liver mitochondria

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Differential rates of metabolic activation and detoxication of the food mutagen 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine by different cytochrome P450 enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Interactions of hepatic cytochromes P-450 with steroid hormones. Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Structure of human steroid 21-hydroxylase genes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Nucleotide sequence of a full-length cDNA coding for 3-methylcholanthrene-induced rat liver cytochrome P-450MC

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

cDNA cloning and sequence and cDNA-directed expression of human P450 IIB1: identification of a normal and two variant cDNAs derived from the CYP2B locus on chromosome 19 and differential expression of the IIB mRNAs in human liver

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Specificity of four forms of cytochrome P-450 in the metabolic activation of several aromatic amines and benzo[a]pyrene.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Nucleotide sequence of a human liver cytochrome P-450 related to the rat male specific form

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Characterization of a cDNA for the unexpressed form of cytochrome P-450g from the (-g) rat and differentiation of its mRNA from that of the (+g) phenotype using specific oligoprobes

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

cDNA cloning of cytochrome P-450 related to P-450p-2 from the cDNA library of human placenta. Gene structure and expression

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Identification and localization of amino acid substitutions between two phenobarbital-inducible rat hepatic microsomal cytochromes P-450 by micro sequence analyses

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

cDNA cloning, sequence, and regulation of a major female-specific and growth hormone-inducible rat liver cytochrome P-450 active in 15 beta-hydroxylation of steroid sulfates.

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Cytochrome P-450 isozyme 1 from phenobarbital-induced rat liver: purification, characterization, and interactions with metyrapone and cytochrome b5

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

Alteration of mouse cytochrome P450coh substrate specificity by mutation of a single amino-acid residue

21 January 2018

1 reference

https://api.crossref.org/works/10.3109%2F00498259209053106

10.3109/00498259209053106

21 January 2018

Identifiers

DOI

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13 August 2017

1 reference