They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection? (Q36267667)

13 August 2017

1 reference

25 October 2022

They Might Be Giants: Does Syncytium Formation Sink or Spread HIV Infection? (English)

1 reference

human immunodeficiency virus infectious disease

13 August 2017

1 reference

1 July 2020

1 reference

3 November 2019

1 reference

12 October 2019

Alex A Compton

1

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Olivier Schwartz

object named as

Olivier Schwartz

series ordinal

2

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publication date

2 February 2017

1 reference

PMCID

5289631

13 August 2017

1 February 2017

6 references

23 March 2019

12 October 2019

19 October 2019

3 November 2019

1 July 2020

25 October 2022

2 references

13 August 2017

25 October 2022

13

1 reference

13 August 2017

e1006099

1 reference

13 August 2017

2

1 reference

Creative Commons Attribution 4.0 International

13 August 2017

1 reference

on focus list of Wikimedia project

25 October 2022

copyright status

copyrighted

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ScienceSource

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cites work

In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Guanylate Binding Protein (GBP) 5 Is an Interferon-Inducible Inhibitor of HIV-1 Infectivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV-1 Envelope Under Attack

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV-1-Induced Small T Cell Syncytia Can Transfer Virus Particles to Target Cells through Transient Contacts

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Cellular Antiviral Factors that Target Particle Infectivity of HIV-1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV-1 Nef promotes infection by excluding SERINC5 from virion incorporation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

SERINC3 and SERINC5 restrict HIV-1 infectivity and are counteracted by Nef

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Large Syncytia in Lymph Nodes Induced by CCR5-Tropic HIV-1.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Unique features of HIV-1 spread through T cell virological synapses

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

IFITM proteins incorporated into HIV-1 virions impair viral fusion and spread.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

IFITM proteins are incorporated onto HIV-1 virion particles and negatively imprint their infectivity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Ezrin is a component of the HIV-1 virological presynapse and contributes to the inhibition of cell-cell fusion.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Evidence showing that tetraspanins inhibit HIV-1-induced cell-cell fusion at a post-hemifusion stage

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV-infected T cells are migratory vehicles for viral dissemination

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Formation of syncytia is repressed by tetraspanins in human immunodeficiency virus type 1-producing cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Cell-cell fusion induced by measles virus amplifies the type I interferon response

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Coupling of human immunodeficiency virus type 1 fusion to virion maturation: a novel role of the gp41 cytoplasmic tail

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Regulation of human immunodeficiency virus type 1 Env-mediated membrane fusion by viral protease activity

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Spread of HTLV-I between lymphocytes by virus-induced polarization of the cytoskeleton

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

The invasive and destructive behavior of HIV-induced T cell syncytia on collagen and endothelium

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Human immunodeficiency virus-infected multinucleated histiocytes in oropharyngeal lymphoid tissues from two asymptomatic patients

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Clustering and mobility of HIV-1 Env at viral assembly sites predict its propensity to induce cell-cell fusion.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

RAGE inhibits human respiratory syncytial virus syncytium formation by interfering with F-protein function

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Maturation-dependent HIV-1 surface protein redistribution revealed by fluorescence nanoscopy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Virus-cell fusion as a trigger of innate immunity dependent on the adaptor STING.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV antigen in the brains of patients with the AIDS dementia complex

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

Detection of AIDS virus in macrophages in brain tissue from AIDS patients with encephalopathy

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

AIDS retrovirus induced cytopathology: giant cell formation and involvement of CD4 antigen

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

In vivo cytolysis and fusion of human immunodeficiency virus type 1-infected lymphocytes in lymphoid tissue

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5289631

HIV-induced T cell syncytia are self-perpetuating and the primary cause of T cell death in culture

22 September 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28152024

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/28152024

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1371/JOURNAL.PPAT.1006099

1 reference

13 August 2017

1 reference

13 August 2017

1 reference

PMCID

5289631