Intrinsic host restrictions to HIV-1 and mechanisms of viral escape. (Q30954229)

27 June 2017

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title

Intrinsic host restrictions to HIV-1 and mechanisms of viral escape (English)

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

author name string

Nicolin Bloch

series ordinal

2

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

Nathaniel R Landau

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

language of work or name

English

0 references

publication date

1 June 2015

1 reference

27 June 2017

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

volume

16

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

page(s)

546-553

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

issue

6

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

Vpx complementation of 'non-macrophage tropic' R5 viruses reveals robust entry of infectious HIV-1 cores into macrophages.

13 May 2020

cites work

1 reference

12 December 2020

Characterization of human disease phenotypes associated with mutations in TREX1, RNASEH2A, RNASEH2B, RNASEH2C, SAMHD1, ADAR, and IFIH1.

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12 December 2020

An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22

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12 December 2020

Inhibition of CUL4A Neddylation causes a reversible block to SAMHD1-mediated restriction of HIV-1

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12 December 2020

Trex1 prevents cell-intrinsic initiation of autoimmunity

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12 December 2020

Cytidine deamination induced HIV-1 drug resistance

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12 December 2020

Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G

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12 December 2020

Vif proteins of human and simian immunodeficiency viruses require cellular CBFβ to degrade APOBEC3 restriction factors

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12 December 2020

Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.

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12 December 2020

The human immunodeficiency virus (HIV) type 2 envelope protein is a functional complement to HIV type 1 Vpu that enhances particle release of heterologous retroviruses.

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12 December 2020

Quantitative profiling of the full APOBEC3 mRNA repertoire in lymphocytes and tissues: implications for HIV-1 restriction

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12 December 2020

Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu

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12 December 2020

Vpx-containing dendritic cell vaccine induces CTLs and reactivates latent HIV-1 in vitro

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12 December 2020

HIV-1 Vif adaptation to human APOBEC3H haplotypes

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12 December 2020

The retroviral restriction ability of SAMHD1, but not its deoxynucleotide triphosphohydrolase activity, is regulated by phosphorylation

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12 December 2020

SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.

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12 December 2020

Induction of APOBEC3G Ubiquitination and Degradation by an HIV-1 Vif-Cul5-SCF Complex

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12 December 2020

An interferon-alpha-induced tethering mechanism inhibits HIV-1 and Ebola virus particle release but is counteracted by the HIV-1 Vpu protein

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12 December 2020

SIV vpx is essential for macrophage infection but not for development of AIDS.

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12 December 2020

APOBEC3G inhibits elongation of HIV-1 reverse transcripts

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12 December 2020

Tetherin inhibits HIV-1 release by directly tethering virions to cells

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12 December 2020

Compensatory changes in the cytoplasmic tail of gp41 confer resistance to tetherin/BST-2 in a pathogenic nef-deleted SIV

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12 December 2020

Kinetic variations between reverse transcriptases of viral protein X coding and noncoding lentiviruses

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12 December 2020

HIV-1 restriction factor SAMHD1 is a deoxynucleoside triphosphate triphosphohydrolase

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12 December 2020

Promiscuous RNA binding ensures effective encapsidation of APOBEC3 proteins by HIV-1.

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12 December 2020

Cyclin L2 is a critical HIV dependency factor in macrophages that controls SAMHD1 abundance

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12 December 2020

APOBEC3G incorporation into human immunodeficiency virus type 1 particles

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12 December 2020

Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes

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12 December 2020

The Vpx lentiviral accessory protein targets SAMHD1 for degradation in the nucleus

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12 December 2020

Ancient adaptive evolution of tetherin shaped the functions of Vpu and Nef in human immunodeficiency virus and primate lentiviruses.

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12 December 2020

Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain

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12 December 2020

Species-specific exclusion of APOBEC3G from HIV-1 virions by Vif

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12 December 2020

Vpx relieves inhibition of HIV-1 infection of macrophages mediated by the SAMHD1 protein

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12 December 2020

SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates

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12 December 2020

Identification of two distinct human immunodeficiency virus type 1 Vif determinants critical for interactions with human APOBEC3G and APOBEC3F.

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12 December 2020

Differential anti-APOBEC3G activity of HIV-1 Vif proteins derived from different subtypes

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12 December 2020

APOBEC3D and APOBEC3F potently promote HIV-1 diversification and evolution in humanized mouse model

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12 December 2020

HIV1 Vpr arrests the cell cycle by recruiting DCAF1/VprBP, a receptor of the Cul4-DDB1 ubiquitin ligase

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12 December 2020

Single-strand specificity of APOBEC3G accounts for minus-strand deamination of the HIV genome

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12 December 2020

Natural variation in Vif: differential impact on APOBEC3G/3F and a potential role in HIV-1 diversification

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12 December 2020

A single amino acid of APOBEC3G controls its species-specific interaction with virion infectivity factor (Vif).

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12 December 2020

CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.

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12 December 2020

Sole copy of Z2-type human cytidine deaminase APOBEC3H has inhibitory activity against retrotransposons and HIV-1

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12 December 2020

The cytosolic exonuclease TREX1 inhibits the innate immune response to human immunodeficiency virus type 1.

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12 December 2020

Functional role of human immunodeficiency virus type 1 vpu.

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12 December 2020

The ribonuclease activity of SAMHD1 is required for HIV-1 restriction

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12 December 2020

APOBEC3G polymorphism as a selective barrier to cross-species transmission and emergence of pathogenic SIV and AIDS in a primate host

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12 December 2020

Cyclic GMP-AMP synthase is an innate immune sensor of HIV and other retroviruses

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12 December 2020

Antiretroelement activity of APOBEC3H was lost twice in recent human evolution

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12 December 2020

Phosphorylation of SAMHD1 by cyclin A2/CDK1 regulates its restriction activity toward HIV-1.

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12 December 2020

Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection

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12 December 2020

Species-specific activity of SIV Nef and HIV-1 Vpu in overcoming restriction by tetherin/BST2

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12 December 2020

The APOBEC3 family of retroelement restriction factors

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12 December 2020

Preservation of tetherin and CD4 counter-activities in circulating Vpu alleles despite extensive sequence variation within HIV-1 infected individuals

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12 December 2020

Stimulation of NF-κB activity by the HIV restriction factor BST2.

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12 December 2020

Nuclease activity of the human SAMHD1 protein implicated in the Aicardi-Goutieres syndrome and HIV-1 restriction.

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12 December 2020

Lentiviral Vif degrades the APOBEC3Z3/APOBEC3H protein of its mammalian host and is capable of cross-species activity

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12 December 2020

Catalytic activity of APOBEC3F is required for efficient restriction of Vif-deficient human immunodeficiency virus

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12 December 2020

Mouse SAMHD1 has antiretroviral activity and suppresses a spontaneous cell-intrinsic antiviral response

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12 December 2020

Differential regulation of NF-κB-mediated proviral and antiviral host gene expression by primate lentiviral Nef and Vpu proteins

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12 December 2020

Evolution of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases.

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12 December 2020

Broad antiretroviral defence by human APOBEC3G through lethal editing of nascent reverse transcripts

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12 December 2020

T-cell differentiation factor CBF-β regulates HIV-1 Vif-mediated evasion of host restriction

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12 December 2020

Vif hijacks CBF-β to degrade APOBEC3G and promote HIV-1 infection

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12 December 2020

Evolution of the primate lentiviruses: evidence from vpx and vpr

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12 December 2020

With a little help from a friend: increasing HIV transduction of monocyte-derived dendritic cells with virion-like particles of SIV(MAC).

1 reference

12 December 2020

Efficient transduction of myeloid cells by an HIV-1-derived lentiviral vector that packages the Vpx accessory protein

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12 December 2020

Direct internalization of cell-surface BST-2/tetherin by the HIV-1 accessory protein Vpu

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12 December 2020

The human immunodeficiency virus type 1-specific protein vpu is required for efficient virus maturation and release

2 references

12 December 2020

Crossref

https://api.crossref.org/works/10.1038%2FNI.3156

7 January 2021

inferred from DOI database lookup

Restriction of diverse retroviruses by SAMHD1.

1 reference

12 December 2020

Human APOBEC3G-mediated editing can promote HIV-1 sequence diversification and accelerate adaptation to selective pressure

1 reference

12 December 2020

Mechanism of HIV-1 virion entrapment by tetherin

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12 December 2020

VPX mutants of HIV-2 are infectious in established cell lines but display a severe defect in peripheral blood lymphocytes

1 reference

12 December 2020

Cytidine deamination of retroviral DNA by diverse APOBEC proteins

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12 December 2020

The vpx gene of simian immunodeficiency virus facilitates efficient viral replication in fresh lymphocytes and macrophage

1 reference

12 December 2020

Human APOBEC3 induced mutation of human immunodeficiency virus type-1 contributes to adaptation and evolution in natural infection

1 reference

12 December 2020

Human immunodeficiency virus type 1 modified to package Simian immunodeficiency virus Vpx efficiently infects macrophages and dendritic cells

1 reference

12 December 2020

Identification of cellular proteins interacting with the retroviral restriction factor SAMHD1

1 reference

12 December 2020

Multiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them all

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12 December 2020

Origin of vpx in lentiviruses

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12 December 2020

Function of human immunodeficiency virus type 1 Vpu protein in various cell types.

1 reference

12 December 2020

Innate sensing of HIV-1 assembly by Tetherin induces NFκB-dependent proinflammatory responses.

1 reference

12 December 2020

Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production

1 reference

12 December 2020

Restriction of HIV-1 by APOBEC3G is cytidine deaminase-dependent

1 reference

12 December 2020

Degradation of SAMHD1 by Vpx Is Independent of Uncoating

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12 December 2020

A zinc-binding region in Vif binds Cul5 and determines cullin selection

1 reference

12 December 2020

Molecular and biochemical analyses of human immunodeficiency virus type 1 vpu protein

1 reference

12 December 2020

APOBEC-mediated viral restriction: not simply editing?

1 reference

12 December 2020

HIV-1 Vif: counteracting innate antiretroviral defenses

1 reference

12 December 2020

Modulation of LINE-1 and Alu/SVA retrotransposition by Aicardi-Goutières syndrome-related SAMHD1.

1 reference

12 December 2020

Gene loss and adaptation to hominids underlie the ancient origin of HIV-1.

1 reference

12 December 2020

Role of SAMHD1 nuclear localization in restriction of HIV-1 and SIVmac

1 reference

12 December 2020

A single amino acid difference in the host APOBEC3G protein controls the primate species specificity of HIV type 1 virion infectivity factor

1 reference

12 December 2020

HIV-1 Vpu promotes release and prevents endocytosis of nascent retrovirus particles from the plasma membrane

1 reference

12 December 2020

The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein

1 reference

12 December 2020

HIV restriction by APOBEC3 in humanized mice

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12 December 2020

SAMHD1 is the dendritic- and myeloid-cell-specific HIV-1 restriction factor counteracted by Vpx

1 reference

12 December 2020

Polymorphisms and splice variants influence the antiretroviral activity of human APOBEC3H

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12 December 2020

Twin gradients in APOBEC3 edited HIV-1 DNA reflect the dynamics of lentiviral replication

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12 December 2020

Natural polymorphisms in human APOBEC3H and HIV-1 Vif combine in primary T lymphocytes to affect viral G-to-A mutation levels and infectivity

1 reference

12 December 2020

Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.

1 reference

12 December 2020

Cell cycle control and HIV-1 susceptibility are linked by CDK6-dependent CDK2 phosphorylation of SAMHD1 in myeloid and lymphoid cells

1 reference

12 December 2020

The HIV 'A' (sor) gene product is essential for virus infectivity

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12 December 2020

Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities

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12 December 2020

SAMHD1 restricts HIV-1 reverse transcription in quiescent CD4(+) T-cells

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12 December 2020

The envelope glycoprotein of human immunodeficiency virus type 2 enhances viral particle release: a Vpu-like factor?

1 reference

12 December 2020

Nef proteins from simian immunodeficiency viruses are tetherin antagonists.

1 reference

12 December 2020

Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein

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12 December 2020

The antiviral factor APOBEC3G improves CTL recognition of cultured HIV-infected T cells

1 reference

12 December 2020

Tailored HIV-1 vectors for genetic modification of primary human dendritic cells and monocytes

1 reference

12 December 2020

A single amino acid determinant governs the species-specific sensitivity of APOBEC3G to Vif action

1 reference

12 December 2020

The antiretroviral enzyme APOBEC3G is degraded by the proteasome in response to HIV-1 Vif

1 reference

12 December 2020

Tight interplay among SAMHD1 protein level, cellular dNTP levels, and HIV-1 proviral DNA synthesis kinetics in human primary monocyte-derived macrophages

1 reference

12 December 2020

The transmembrane domain of HIV-1 Vpu is sufficient to confer anti-tetherin activity to SIVcpz and SIVgor Vpu proteins: cytoplasmic determinants of Vpu function

1 reference

12 December 2020

RNA editing enzyme APOBEC1 and some of its homologs can act as DNA mutators

1 reference

12 December 2020

SAMHD1-dependent retroviral control and escape in mice.

1 reference

12 December 2020

Partially active HIV-1 Vif alleles facilitate viral escape from specific antiretrovirals

1 reference

12 December 2020

Evidence for a newly discovered cellular anti-HIV-1 phenotype

1 reference

12 December 2020

Aicardi-Goutieres syndrome gene and HIV-1 restriction factor SAMHD1 is a dGTP-regulated deoxynucleotide triphosphohydrolase

1 reference

12 December 2020

The activity spectrum of Vif from multiple HIV-1 subtypes against APOBEC3G, APOBEC3F, and APOBEC3H

1 reference

12 December 2020

Vpr.A3A chimera inhibits HIV replication

1 reference

12 December 2020

Human immunodeficiency virus type 1 Vpu protein regulates the formation of intracellular gp160-CD4 complexes

1 reference

12 December 2020

The ability of primate lentiviruses to degrade the monocyte restriction factor SAMHD1 preceded the birth of the viral accessory protein Vpx.

1 reference

12 December 2020

Identifiers

DOI

10.1038/NI.3156

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

Dimensions Publication ID

13 May 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=PMCID:PMC6908429&resulttype=core&format=json

13 May 2020

1 reference