HIV-1 induces telomerase activity in monocyte-derived macrophages, possibly safeguarding one of its reservoirs. (Q36276462)

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7 February 2020

title

HIV-1 induces telomerase activity in monocyte-derived macrophages, possibly safeguarding one of its reservoirs (English)

1 reference

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7 February 2020

author

Diego Sebastian Ojeda

3

1 reference

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7 February 2020

Harald Kühnel

5

1 reference

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7 February 2020

Regina Grillari-Voglauer

8

1 reference

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7 February 2020

Johannes Grillari

9

1 reference

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7 February 2020

2

Matthias Wieser

1 reference

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7 February 2020

1

Rita Reynoso

1 reference

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7 February 2020

Regina Grillari-Voglauer

10

object named as

Regina Grillari-Voglauer

1 reference

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7 February 2020

11

Jorge Quarleri

1 reference

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7 February 2020

author name string

Maximilian Bönisch

4

1 reference

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7 February 2020

Federico Bolcic

6

1 reference

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7 February 2020

Heribert Quendler

7

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7 February 2020

language of work or name

English

0 references

publication date

11 July 2012

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7 February 2020

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7 February 2020

volume

86

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7 February 2020

issue

19

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7 February 2020

page(s)

10327-10337

1 reference

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Human telomerase acts as a hTR-independent reverse transcriptase in mitochondria

7 February 2020

cites work

1 reference

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Inhibition of telomerase activity alters tight junction protein expression and induces transendothelial migration of HIV-1-infected cells

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Telomerase, mitochondria and oxidative stress.

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Telomere length measurement by a novel monochrome multiplex quantitative PCR method

30 September 2017

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Tat-induced FOXO3a is a key mediator of apoptosis in HIV-1-infected human CD4+ T lymphocytes

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Cellular reservoirs of HIV-1 and their role in viral persistence

30 September 2017

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Constitutive activation of phosphatidylinositol 3-kinase signaling pathway down-regulates TLR4-mediated tumor necrosis factor-alpha release in alveolar macrophages from asymptomatic HIV-positive persons in vitro

30 September 2017

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30 September 2017

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Telomerase activity of HIV-1-specific CD8+ T cells: constitutive up-regulation in controllers and selective increase by blockade of PD ligand 1 in progressors

30 September 2017

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hTERT alone immortalizes epithelial cells of renal proximal tubules without changing their functional characteristics.

30 September 2017

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Nef and TNFalpha are coplayers that favor HIV-1 replication in monocytic cells and primary macrophages

30 September 2017

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Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway

30 September 2017

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Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy

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Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages

30 September 2017

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STAT3 and PKC differentially regulate telomerase activity during megakaryocytic differentiation of K562 cells

30 September 2017

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HIV Tat protein increases Bcl-2 expression in monocytes which inhibits monocyte apoptosis induced by tumor necrosis factor-alpha-related apoptosis-induced ligand

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Techniques in gerontology: cell lines as standards for telomere length and telomerase activity assessment

30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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30 September 2017

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Comparison of early passage, senescent and hTERT immortalized endothelial cells.

30 September 2017

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HIV-1 viral proteins gp120 and Tat induce oxidative stress in brain endothelial cells

30 September 2017

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30 September 2017

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Identification of granulocyte-macrophage colony-stimulating factor and lipopolysaccharide-induced signal transduction pathways that synergize to stimulate HIV type 1 production by monocytes from HIV type 1 transgenic mice

30 September 2017

1 reference

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Identification of two distinct elements mediating activation of telomerase (hTERT) gene expression in association with cell growth in human T cells.

30 September 2017

1 reference

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Telomerase as a Growth-Promoting Factor

30 September 2017

1 reference

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Macrophage HIV-1 infection and the gastrointestinal tract reservoir

30 September 2017

1 reference

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Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.

30 September 2017

1 reference

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Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages

30 September 2017

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HIV-1 persistence, viral reservoir, and the central nervous system in the HAART era.

30 September 2017

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Comparing the ex vivo fitness of CCR5-tropic human immunodeficiency virus type 1 isolates of subtypes B and C.

30 September 2017

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The macrophage response to HIV-1: Intracellular control of X4 virus replication accompanied by activation of chemokine and cytokine synthesis

30 September 2017

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The role of monocytes and macrophages in the pathogenesis of HIV-1 infection

30 September 2017

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Telomere measurement by quantitative PCR

30 September 2017

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Induction of rapid and extensive beta-chemokine synthesis in macrophages by human immunodeficiency virus type 1 and gp120, independently of their coreceptor phenotype

30 September 2017

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Telomerase expression and activity are coupled with myocyte proliferation and preservation of telomeric length in the failing heart

30 September 2017

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Substance P antagonist (CP-96,345) inhibits HIV-1 replication in human mononuclear phagocytes

30 September 2017

1 reference

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Regulation of scavenger receptor CD163 expression in human monocytes and macrophages by pro- and antiinflammatory stimuli

30 September 2017

1 reference

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Regulated expression of telomerase activity in human T lymphocyte development and activation

30 September 2017

1 reference

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Telomerase activation in atherosclerosis and induction of telomerase reverse transcriptase expression by inflammatory stimuli in macrophages

30 September 2017

1 reference

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Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage

29 June 2018

1 reference

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Oxidative stress activates protein tyrosine kinase and matrix metalloproteinases leading to blood-brain barrier dysfunction

29 June 2018

1 reference

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Tissue-resident macrophages are productively infected ex vivo by primary X4 isolates of human immunodeficiency virus type 1.

29 June 2018

1 reference

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Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus

29 June 2018

1 reference

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Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.

29 June 2018

1 reference

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Telomerase activity in peripheral blood mononuclear cells from HIV and HIV-HCV coinfected patients

29 June 2018

1 reference

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The loss of telomerase activity in highly differentiated CD8+CD28-CD27- T cells is associated with decreased Akt (Ser473) phosphorylation.

22 September 2018

1 reference

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Telomerase activity, hTERT expression, and phosphorylation are downregulated in CD4(+) T lymphocytes infected with human immunodeficiency virus type 1 (HIV-1).

22 September 2018

1 reference

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Macrophage activation and human immunodeficiency virus infection: HIV replication directs macrophages towards a pro-inflammatory phenotype while previous activation modulates macrophage susceptibility to infection and viral production

22 September 2018

1 reference

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HIV-Tat down-regulates telomerase activity in the nucleus of human CD4+ T cells

22 September 2018

1 reference

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Human telomerase reverse transcriptase mRNA is highly expressed in normal breast tissues and down-regulated in ductal carcinoma in situ.

22 September 2018

1 reference

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Telomerase maintains telomere structure in normal human cells.

22 September 2018

1 reference

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Telomerase can extend the proliferative capacity of human myoblasts, but does not lead to their immortalization.

22 September 2018

1 reference

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HIV-Tat protein induces oxidative and inflammatory pathways in brain endothelium

22 September 2018

1 reference

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The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophages

22 September 2018

1 reference

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Analysis of cellular factors influencing the replication of human immunodeficiency virus type I in human macrophages derived from blood of different healthy donors

22 September 2018

1 reference

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The susceptibility of macrophages to human immunodeficiency virus type 1 X4 isolates depends on their activation state

22 September 2018

1 reference

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Human immunodeficiency virus type 1 modulates telomerase activity in peripheral blood lymphocytes

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3457250

Telomerase is active in normal gastrointestinal mucosa and not up-regulated in precancerous lesions

22 September 2018

1 reference

12 December 2020

Donor variation in in vitro HIV-1 susceptibility of monocyte-derived macrophages

1 reference

12 December 2020

HIV-1 Nef protects human-monocyte-derived macrophages from HIV-1-induced apoptosis

1 reference

12 December 2020

Real-time quantitative telomeric repeat amplification protocol assay for the detection of telomerase activity

1 reference

12 December 2020

TERT regulates cell survival independent of telomerase enzymatic activity

1 reference

12 December 2020

Expression and characterization of the catalytic subunit of telomerase in normal and cataractous canine lens epithelial cells

1 reference

12 December 2020

Dramatic increase of telomerase activity during dendritic cell differentiation and maturation

1 reference

12 December 2020

Telomerase modulates expression of growth-controlling genes and enhances cell proliferation

1 reference

12 December 2020

Telomerase activity in normal human epithelial cells

1 reference

12 December 2020

Telomerase does not counteract telomere shortening but protects mitochondrial function under oxidative stress

1 reference

12 December 2020

Nonradioactive detection of telomerase activity using the telomeric repeat amplification protocol

1 reference

12 December 2020

HIV-1 infection downregulates nuclear telomerase activity on lymphoblastoic cells without affecting the enzymatic components at the transcriptional level

1 reference

12 December 2020

Akt protein kinase enhances human telomerase activity through phosphorylation of telomerase reverse transcriptase subunit

1 reference

12 December 2020

Identifiers

DOI

10.1128/JVI.01495-12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787205%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22787205%20AND%20SRC:MED&resulttype=core&format=json

7 February 2020

PubMed publication ID

22787205

1 reference