Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs (Q36279894)

13 August 2017

Synthesis, cellular evaluation, and mechanism of action of piperlongumine analogs (English)

1 reference

13 August 2017

7

Stuart L Schreiber

1 reference

13 August 2017

Drew J Adams

1

1 reference

13 August 2017

Mingji Dai

2

1 reference

13 August 2017

Giovanni Pellegrino

3

1 reference

13 August 2017

Bridget K Wagner

4

1 reference

13 August 2017

Andrew M Stern

5

1 reference

13 August 2017

Alykhan F Shamji

6

1 reference

13 August 2017

language of work or name

English

0 references

publication date

4 September 2012

1 reference

Proceedings of the National Academy of Sciences of the United States of America

13 August 2017

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13 August 2017

109

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13 August 2017

38

1 reference

13 August 2017

15115-15120

1 reference

Enhanced toxicity of the protein cross-linkers divinyl sulfone and diethyl acetylenedicarboxylate in comparison to related monofunctional electrophiles

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

RETRACTED: Selective killing of cancer cells by a small molecule targeting the stress response to ROS

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Reversible and irreversible protein glutathionylation: biological and clinical aspects

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Selective killing of K-ras mutant cancer cells by small molecule inducers of oxidative stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

S-nitrosoproteome in endothelial cells revealed by a modified biotin switch approach coupled with Western blot-based two-dimensional gel electrophoresis

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Redox-directed cancer therapeutics: molecular mechanisms and opportunities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Covalent cross-linking of glutathione and carnosine to proteins by 4-oxo-2-nonenal

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Principles of cancer therapy: oncogene and non-oncogene addiction

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Design and Applications of Bifunctional Small Molecules: Why Two Heads Are Better Than One.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

GSH loss per se does not affect neuroblastoma survival and is not genotoxic.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Molecular mechanisms and potential clinical significance of S-glutathionylation.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Protein damage by reactive electrophiles: targets and consequences

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Intracellular water-specific MR of microbead-adherent cells: the HeLa cell intracellular water exchange lifetime

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Reactive oxygen species: a breath of life or death?

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Selective killing of oncogenically transformed cells through a ROS-mediated mechanism by beta-phenylethyl isothiocyanate.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

The role of glutathione in disulphide bond formation and endoplasmic-reticulum-generated oxidative stress.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Extremely potent triterpenoid inducers of the phase 2 response: correlations of protection against oxidant and inflammatory stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Protein S-thiolation targets glycolysis and protein synthesis in response to oxidative stress in the yeast Saccharomyces cerevisiae

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Proteomics analysis of cellular response to oxidative stress. Evidence for in vivo overoxidation of peroxiredoxins at their active site

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Regulation of protein function by S-glutathiolation in response to oxidative and nitrosative stress

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Creation of human tumour cells with defined genetic elements

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Production of large amounts of hydrogen peroxide by human tumor cells

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3458345

Synthesis and structure-activity relationships of 6,7-disubstituted 4-anilinoquinoline-3-carbonitriles. The design of an orally active, irreversible inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR) and the hum

30 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1212802109

Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1212802109

Synthesis and evaluation of a fluorogenic reagent for proteomic studies: 7-fluoro-N-[2-(dimethylamino)ethyl]-2,1,3-benzoxadiazole-4-sulfonamide (DAABD-F).

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1212802109

Superoxide dismutase as a target for the selective killing of cancer cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1212802109

Ras proteins induce senescence by altering the intracellular levels of reactive oxygen species

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22949699

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Lack of mitochondrial depolarization by oxidative stress is associated with resistance to buthionine sulfoximine in acute lymphoblastic leukemia cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22949699

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1212802109

1 reference

13 August 2017

0 references

1 reference

13 August 2017

1 reference