CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection (Q36281282)

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English	CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection	scientific article

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scholarly article

1 reference

Europe PubMed Central

13 August 2017

CD8+ T cell exhaustion, suppressed gamma interferon production, and delayed memory response induced by chronic Brucella melitensis infection (English)

1 reference

Europe PubMed Central

13 August 2017

T cell exhaustion

1 reference

based on heuristic

inferred from title

Brucella melitensis

object named as

Brucella melitensis

1 reference

based on heuristic

inferred from title

author name string

Marina Durward-Diioia

1

1 reference

Europe PubMed Central

13 August 2017

Jerome Harms

2

1 reference

Europe PubMed Central

13 August 2017

Mike Khan

3

1 reference

Europe PubMed Central

13 August 2017

Cherisse Hall

4

1 reference

Europe PubMed Central

13 August 2017

Judith A Smith

5

1 reference

Europe PubMed Central

13 August 2017

Gary A Splitter

6

1 reference

Europe PubMed Central

13 August 2017

language of work or name

0 references

publication date

28 September 2015

1 reference

Europe PubMed Central

13 August 2017

Infection and Immunity

1 reference

Europe PubMed Central

13 August 2017

83

1 reference

Europe PubMed Central

13 August 2017

4759-4771

1 reference

Europe PubMed Central

13 August 2017

12

1 reference

Europe PubMed Central

13 August 2017

CD8+ regulatory T cells, and not CD4+ T cells, dominate suppressive phenotype and function after in vitro live Mycobacterium bovis-BCG activation of human cells

1 reference

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30 September 2017

The influence of intrinsic and extrinsic factors on immune system aging

1 reference

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Enhancing virus-specific immunity in vivo by combining therapeutic vaccination and PD-L1 blockade in chronic hepadnaviral infection

1 reference

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30 September 2017

Brucella induces an unfolded protein response via TcpB that supports intracellular replication in macrophages

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Two separate defects affecting true naive or virtual memory T cell precursors combine to reduce naive T cell responses with aging

1 reference

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30 September 2017

The who's who of T-cell differentiation: human memory T-cell subsets

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Tolerance and exhaustion: defining mechanisms of T cell dysfunction

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Programmed death 1-mediated T cell exhaustion during visceral leishmaniasis impairs phagocyte function

1 reference

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30 September 2017

Lack of endogenous IL-10 enhances production of proinflammatory cytokines and leads to Brucella abortus clearance in mice

1 reference

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30 September 2017

PD-L1 blockade synergizes with IL-2 therapy in reinvigorating exhausted T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

PD-1 coinhibitory signals: the link between pathogenesis and protection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Brucella evasion of adaptive immunity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

T-cell memory differentiation: insights from transcriptional signatures and epigenetics.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Transcriptional control of effector and memory CD8+ T cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Crucial role of gamma interferon-producing CD4+ Th1 cells but dispensable function of CD8+ T cell, B cell, Th2, and Th17 responses in the control of Brucella melitensis infection in mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

B Lymphocytes provide an infection niche for intracellular bacterium Brucella abortus

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Active evasion of CTL mediated killing and low quality responding CD8+ T cells contribute to persistence of brucellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Signal integration by Akt regulates CD8 T cell effector and memory differentiation.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Mechanisms controlling granule-mediated cytolytic activity of cytotoxic T lymphocytes

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

The PD-1/PD-L1 (B7-H1) pathway in chronic infection-induced cytotoxic T lymphocyte exhaustion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Confronting the barriers to develop novel vaccines against brucellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

CD8(+) T cells: foot soldiers of the immune system

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Tight regulation of memory CD8(+) T cells limits their effectiveness during sustained high viral load

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

T cell exhaustion

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Cytokines and the inception of CD8 T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

The CD4-like molecule LAG-3, biology and therapeutic applications

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Differential localization of effector and memory CD8 T cell subsets in lymphoid organs during acute viral infection.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Making memories that last a lifetime: heritable functions of self-renewing memory CD8 T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Generation of effector CD8+ T cells and their conversion to memory T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Early events governing memory CD8+ T-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Viral Vaccines and CTL Response

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Shaping successful and unsuccessful CD8 T cell responses following infection

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Discordant Brucella melitensis antigens yield cognate CD8+ T cells in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Regulatory T cells: how do they suppress immune responses?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Induction of peripheral CD4+ T-cell tolerance and CD8+ T-cell cross-tolerance by dendritic cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Neglected and endemic zoonoses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

mTOR regulates memory CD8 T-cell differentiation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Surviving the crash: transitioning from effector to memory CD8+ T cell

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Brucella TIR Domain-containing Protein Mimics Properties of the Toll-like Receptor Adaptor Protein TIRAP.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Functional and genomic profiling of effector CD8 T cell subsets with distinct memory fates

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Human brucellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Activation-induced non-responsiveness (anergy) limits CD8 T cell responses to tumors

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Persistence and relapse in brucellosis and need for improved treatment

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Molecular mechanisms for adaptive tolerance and other T cell anergy models

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Molecular basis for checkpoints in the CD8 T cell response: tolerance versus activation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Host immune responses to the intracellular bacteria Brucella: does the bacteria instruct the host to facilitate chronic infection?

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

A reappraisal of humoral immunity based on mechanisms of antibody-mediated protection against intracellular pathogens

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Stable T cell-dendritic cell interactions precede the development of both tolerance and immunity in vivo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Molecular host-pathogen interaction in brucellosis: current understanding and future approaches to vaccine development for mice and humans

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

30 September 2017

Brucella abortus induces intracellular retention of MHC-I molecules in human macrophages down-modulating cytotoxic CD8(+) T cell responses

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

29 June 2018

CD8+ type 1 CD44hi CD45 RBlo T lymphocytes control intracellular Brucella abortus infection as demonstrated in major histocompatibility complex class I- and class II-deficient mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

29 June 2018

Studying host-pathogen interaction events in living mice visualized in real time using biophotonic imaging.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

22 September 2018

Humoral immunity and CD4+ Th1 cells are both necessary for a fully protective immune response upon secondary infection with Brucella melitensis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

22 September 2018

Recombinant bovine interleukin 2 enhances immunity and protection induced by Brucella abortus vaccines in cattle.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

22 September 2018

Susceptibility of IFN regulatory factor-1 and IFN consensus sequence binding protein-deficient mice to brucellosis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

22 September 2018

CD4+CD25+ T regulatory cells limit effector T cells and favor the progression of brucellosis in BALB/c mice

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4645381

21 October 2018

Temporal analysis of pathogenic events in virulent and avirulent Brucella melitensis infections

1 reference

https://pubmed.ncbi.nlm.nih.gov/26416901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

B cell-deficient mice display markedly enhanced resistance to the intracellular bacterium Brucella abortus

1 reference

https://pubmed.ncbi.nlm.nih.gov/26416901

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/IAI.01184-15

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

1 reference

Europe PubMed Central

13 August 2017

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