Functional MT1 and MT2 melatonin receptors in mammals (Q36282807)

13 August 2017

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title

Functional MT1 and MT2 melatonin receptors in mammals (English)

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13 August 2017

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Margarita L Dubocovich

series ordinal

1

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PubMed ID

16217123

13 August 2017

Magdalena Markowska

series ordinal

2

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13 August 2017

1 July 2005

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13 August 2017

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13 August 2017

27

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13 August 2017

101-110

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13 August 2017

2

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https://scigraph.springernature.com/pub.10.1385/endo:27:2:101

13 August 2017

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cites work

Key MT2 melatonin receptor citation still buried - dig deeper!

1 reference

12 December 2020

Melatonin and serotonin directly regulate oxytocin, insulin-like growth factor-I and progesterone secretion by cultured human granulosa cells

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12 December 2020

Involvement of the mt1 melatonin receptor in human breast cancer

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12 December 2020

Receptor (MT(1)) mediated influence of melatonin on cAMP concentration and insulin secretion of rat insulinoma cells INS-1.

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12 December 2020

Melatonin: a coordinating signal for mammalian reproduction?

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12 December 2020

Effects of melatonin on spontaneous electrical activity of neurons in rat suprachiasmatic nuclei: an in vitro iontophoretic study

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12 December 2020

Melatonin mediates two distinct responses in vascular smooth muscle

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12 December 2020

Twenty-four hour pattern of the episodic secretion of cortisol in normal subjects

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12 December 2020

Neural control of the pineal gland

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12 December 2020

17Beta-estradiol modulates hMT1 melatonin receptor function

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12 December 2020

Effects of melatonin on neuronal activity in the rat suprachiasmatic nucleus in vitro

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12 December 2020

MT(1) melatonin receptor overexpression enhances the growth suppressive effect of melatonin in human breast cancer cells

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12 December 2020

Differential expression of high-affinity melatonin receptors (MT1) in normal and malignant human breast tissue

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12 December 2020

Melatonin-mediated regulation of human MT(1) melatonin receptors expressed in mammalian cells

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12 December 2020

Melatonin synthesis pathway: circadian regulation of the genes encoding the key enzymes in the chicken pineal gland and retina

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12 December 2020

Evidence for a melatonin receptor within pancreatic islets of neonate rats: functional, autoradiographic, and molecular investigations

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12 December 2020

Melatonin receptors mediate potentiation of contractile responses to adrenergic nerve stimulation in rat caudal artery

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12 December 2020

The melatonin receptor subtype MT1 is expressed in human gallbladder epithelia

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12 December 2020

Nobel Lecture. G proteins and regulation of adenylyl cyclase

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12 December 2020

Expression of membrane and nuclear melatonin receptor mRNA and protein in the mouse immune system

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12 December 2020

No evidence for a phase delay in human circadian rhythms after a single morning melatonin administration

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12 December 2020

Down-regulation of mt1 melatonin receptors in rat ovary following estrogen exposure.

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12 December 2020

Identification and functional characterization of melatonin Mel 1a receptors in pancreatic beta cells: potential role in incretin-mediated cell function by sensitization of cAMP signaling

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12 December 2020

Melatonin synthesis in the rat harderian gland: age- and time-related effects

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12 December 2020

Adrenal hormones mediate melatonin-induced increases in aggression in male Siberian hamsters (Phodopus sungorus).

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12 December 2020

Molecular pharmacology, regulation and function of mammalian melatonin receptors

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12 December 2020

Circadian and seasonal variation in human preovulatory follicular fluid melatonin concentration

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12 December 2020

mt1 Melatonin receptor in the primate adrenal gland: inhibition of adrenocorticotropin-stimulated cortisol production by melatonin.

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12 December 2020

Transcription factor dynamics and neuroendocrine signalling in the mouse pineal gland: a comparative analysis of melatonin-deficient C57BL mice and melatonin-proficient C3H mice

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12 December 2020

MT1 melatonin receptor mRNA expression exhibits a circadian variation in the rat suprachiasmatic nuclei

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12 December 2020

Maternal melatonin selectively inhibits cortisol production in the primate fetal adrenal gland.

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12 December 2020

Biology of mammalian photoperiodism and the critical role of the pineal gland and melatonin

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12 December 2020

Melatonin inhibition of GnRH-induced LH release from neonatal rat gonadotroph: involvement of Ca2+ not cAMP

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12 December 2020

Melatonin limits transcriptional impact of phosphoCREB in the mouse SCN via the Mel1a receptor

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12 December 2020

The melatonin rhythm: both a clock and a calendar

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12 December 2020

Human lymphocyte-synthesized melatonin is involved in the regulation of the interleukin-2/interleukin-2 receptor system.

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12 December 2020

Melatonin receptor-mediated stimulation of phosphoinositide breakdown in chick brain slices

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12 December 2020

Molecular analysis of mammalian circadian rhythms

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12 December 2020

Melatonin receptors step into the light: cloning and classification of subtypes

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12 December 2020

Melatonin action in the pituitary: neuroendocrine synchronizer and developmental modulator?

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12 December 2020

Gastrointestinal melatonin: localization, function, and clinical relevance

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12 December 2020

The electrophysiological effects of melatonin and a putative melatonin antagonist (N-acetyltryptamine) on rat suprachiasmatic neurones in vitro

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12 December 2020

Regulation of melatonin 1a receptor signaling and trafficking by asparagine-124.

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12 December 2020

Photoperiodic responses in Djungarian hamsters (Phodopus sungorus): importance of light history for pineal and serum melatonin profiles

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12 December 2020

Overexpression of the MT1 melatonin receptor in MCF-7 human breast cancer cells inhibits mammary tumor formation in nude mice

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12 December 2020

Selective MT2 melatonin receptor antagonists block melatonin-mediated phase advances of circadian rhythms

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12 December 2020

Dopaminergic and GABAergic amacrine cells are direct targets of melatonin: immunocytochemical study of mt1 melatonin receptor in guinea pig retina.

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12 December 2020

Evidence of melatonin synthesis by human lymphocytes and its physiological significance: possible role as intracrine, autocrine, and/or paracrine substance.

1 reference

12 December 2020

Melatonin as a chronobiotic/anticancer agent: cellular, biochemical, and molecular mechanisms of action and their implications for circadian-based cancer therapy

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12 December 2020

Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors

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12 December 2020

Targeted disruption of the mouse Mel(1b) melatonin receptor

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12 December 2020

Melatonin and mammary cancer: a short review

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12 December 2020

Organization of the mammalian circadian system.

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12 December 2020

Melatonin action in neonatal gonadotrophs.

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12 December 2020

Biochemical reactivity of melatonin with reactive oxygen and nitrogen species: a review of the evidence

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12 December 2020

Melatonin receptors in human hypothalamus and pituitary: implications for circadian and reproductive responses to melatonin.

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12 December 2020

Functional melatonin receptors in rat ovaries at various stages of the estrous cycle

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12 December 2020

Rhythmic gene expression in pituitary depends on heterologous sensitization by the neurohormone melatonin

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12 December 2020

Melatonin modulates vascular smooth muscle tone

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12 December 2020

Molecular dissection of two distinct actions of melatonin on the suprachiasmatic circadian clock.

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12 December 2020

Oncostatic action of melatonin: facts and question marks

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12 December 2020

Putative melatonin receptors in a human biological clock.

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12 December 2020

Melatonin receptors activate heteromeric G-protein coupled Kir3 channels.

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12 December 2020

Melatonin mediates seasonal changes in immune function

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12 December 2020

Melatonin enhancement of splenocyte proliferation is attenuated by luzindole, a melatonin receptor antagonist

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12 December 2020

Expression of mt1 melatonin receptor in rat retina: evidence for multiple cell targets for melatonin

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12 December 2020

G protein-linked effector and second messenger systems involved in melatonin signal transduction

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12 December 2020

Morphological changes of thymus and the thyroid gland after postnatal extirpation of pineal body

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12 December 2020

Melatonin action and signal transduction in the rat suprachiasmatic circadian clock: activation of protein kinase C at dusk and dawn

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12 December 2020

Melatonin as a chronobiotic.

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12 December 2020

Effect of MT1 melatonin receptor deletion on melatonin-mediated phase shift of circadian rhythms in the C57BL/6 mouse

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12 December 2020

Immortalized suprachiasmatic nucleus cells express components of multiple circadian regulatory pathways

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12 December 2020

Physiological exposure to melatonin supersensitizes the cyclic adenosine 3',5'-monophosphate-dependent signal transduction cascade in Chinese hamster ovary cells expressing the human mt1 melatonin receptor

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12 December 2020

Melatonin and N-acetylserotonin inhibit leukocyte rolling and adhesion to rat microcirculation.

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12 December 2020

Melatonin activates an outward current and inhibits Ih in rat suprachiasmatic nucleus neurons

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12 December 2020

Distribution of melatonin MT1 receptor immunoreactivity in human retina

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12 December 2020

Melatonin counteracts the inhibitory effect of PGE2 on IL-2 production in human lymphocytes via its mt1 membrane receptor

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12 December 2020

Melatonin: the chemical expression of darkness

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12 December 2020

Studies of the renal action of melatonin: evidence that the effects are mediated by 37 kDa receptors of the Mel1a subtype localized primarily to the basolateral membrane of the proximal tubule

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12 December 2020

Melatonin receptor mRNA expression in human granulosa cells

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12 December 2020

Physiological roles and properties of potassium channels in arterial smooth muscle

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12 December 2020

Physiological and metabolic functions of melatonin

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12 December 2020

Inhibition of malignant trophoblastic cell proliferation in vitro and in vivo by melatonin.

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12 December 2020

Identification of cysteines involved in ligand binding to the human melatonin MT(2) receptor

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12 December 2020

Melatonin as a hypnotic: pro.

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12 December 2020

Melatonin improves cerebral circulation security margin in rats.

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12 December 2020

Inhibition of isoproterenol-induced lipolysis in rat inguinal adipocytes in vitro by physiological melatonin via a receptor-mediated mechanism

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12 December 2020

Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3.

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12 December 2020

Melatonin receptor antagonists that differentiate between the human Mel1a and Mel1b recombinant subtypes are used to assess the pharmacological profile of the rabbit retina ML1 presynaptic heteroreceptor

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12 December 2020

MT(2) melatonin receptors are present and functional in rat caudal artery

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12 December 2020

Mapping of the gene for the Mel1a-melatonin receptor to human chromosome 4 (MTNR1A) and mouse chromosome 8 (Mtnr1a)

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12 December 2020

Bidirectional communication between the pineal gland and the immune system.

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12 December 2020

Activation of MT(2) melatonin receptors in rat suprachiasmatic nucleus phase advances the circadian clock

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12 December 2020

Melatonin desensitizes endogenous MT2 melatonin receptors in the rat suprachiasmatic nucleus: relevance for defining the periods of sensitivity of the mammalian circadian clock to melatonin

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12 December 2020

Cerebrovascular melatonin MT1-receptor alterations in patients with Alzheimer's disease

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12 December 2020

2-[125I]iodo-5-methoxycarbonylamino-N-acetyltryptamine: a selective radioligand for the characterization of melatonin ML2 binding sites

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12 December 2020

Regulation of melatonin biosynthesis in vertebrate retina: involvement of dopamine in the suppressive effects of light

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12 December 2020

Ocular hypotensive effects of melatonin receptor agonists in the rabbit: further evidence for an MT3 receptor

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12 December 2020

Melatonin is a potent modulator of dopamine release in the retina.

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12 December 2020

Melatonin receptors: are there multiple subtypes?

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12 December 2020

Short-term exposure to melatonin differentially affects the functional sensitivity and trafficking of the hMT1 and hMT2 melatonin receptors

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12 December 2020

Melatonin-induced inhibition of proliferation and G1/S cell cycle transition delay of human choriocarcinoma JAr cells: possible involvement of MT2 (MEL1B) receptor

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12 December 2020

Effect of melatonin in the rat tail artery: role of K+ channels and endothelial factors

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12 December 2020

Magic shotguns versus magic bullets: selectively non-selective drugs for mood disorders and schizophrenia

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12 December 2020

MLT and the immune-hematopoietic system

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12 December 2020

Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2 .

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12 December 2020

Signaling in the suprachiasmatic nucleus: selectively responsive and integrative

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12 December 2020

Developmental changes and daily rhythm in melatonin-induced inhibition of 3',5'-cyclic AMP accumulation in the rat pituitary.

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12 December 2020

Cyclical regulation of GnRH gene expression in GT1-7 GnRH-secreting neurons by melatonin

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12 December 2020

MT-1 melatonin receptor expression increases the antiproliferative effect of melatonin on S-91 murine melanoma cells

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12 December 2020

Differential growth inhibitory effect of melatonin on two endometrial cancer cell lines

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12 December 2020

MT(1) melatonin receptor in the human retina: expression and localization

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12 December 2020

Photic and neural control of indoleamine metabolism in the rat pineal gland.

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12 December 2020

Inhibition of androgen-sensitive LNCaP prostate cancer growth in vivo by melatonin: association of antiproliferative action of the pineal hormone with mt1 receptor protein expression

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12 December 2020

Gonadotrophin-releasing hormone drives melatonin receptor down-regulation in the developing pituitary gland.

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12 December 2020

Design of subtype selective melatonin receptor agonists and antagonists

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12 December 2020

Direct effect of melatonin on Syrian hamster testes: melatonin subtype 1a receptors, inhibition of androgen production, and interaction with the local corticotropin-releasing hormone system

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12 December 2020

Evolving concepts in G protein-coupled receptor endocytosis: the role in receptor desensitization and signaling

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12 December 2020

Melatonin receptor subtype MT2 (Mel 1b) and not mt1 (Mel 1a) is associated with melatonin-induced enhancement of cell-mediated and humoral immunity

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12 December 2020

Melatonin and light induce phase shifts of circadian activity rhythms in the C3H/HeN mouse

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12 December 2020

Direct action of melatonin in human granulosa-luteal cells

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12 December 2020

Melatonin in the rat testis: evidence for local synthesis.

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12 December 2020

Identification of the melatonin-binding site MT3 as the quinone reductase 2.

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12 December 2020

Melatonin inhibition of the in vivo pituitary response to luteinizing hormone-releasing hormone in the neonatal rat

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12 December 2020

Melatonin in human preovulatory follicular fluid

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12 December 2020

Melatonin and the seasonal control of reproduction

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12 December 2020

N1E-115 mouse neuroblastoma cells express MT1 melatonin receptors and produce neurites in response to melatonin

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12 December 2020

Pharmacological characterization of human recombinant melatonin mt(1) and MT(2) receptors

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12 December 2020

Cellular mechanisms of melatonin action.

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12 December 2020

Melatonin enhances leptin expression by rat adipocytes in the presence of insulin.

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12 December 2020

Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands

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12 December 2020

Photoperiodic regulation of prolactin secretion: changes in intra-pituitary signalling and lactotroph heterogeneity

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12 December 2020

Mutagenesis studies of the human MT2 melatonin receptor

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12 December 2020

Melatonin receptor subtype expression in human cerebellum

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12 December 2020

Melatonin receptor signaling: finding the path through the dark

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12 December 2020

Luzindole (N-0774): a novel melatonin receptor antagonist.

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12 December 2020

Clock genes and the long-term regulation of prolactin secretion: evidence for a photoperiod/circannual timer in the pars tuberalis

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12 December 2020

Expression of melatonin receptors in arteries involved in thermoregulation

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12 December 2020

Autoradiographic localization of 2-[125I]iodomelatonin binding sites in the brains of C3H/HeN and C57BL/6J strains of mice.

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12 December 2020

Melatonin MT-1-receptor immunoreactivity in the human eye.

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12 December 2020

Expression of melatonin MT(1) and MT(2) receptors, and ROR alpha(1) receptor in transplantable murine Colon 38 cancer.

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12 December 2020

Melatonin-immune system relationships

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12 December 2020

Digging deep – structure–function relationships in the melatonin receptor family

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12 December 2020

Functional link between distal vasodilation and sleep-onset latency?

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12 December 2020

The melatonin rhythm-generating enzyme: molecular regulation of serotonin N-acetyltransferase in the pineal gland

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12 December 2020

The Pineal and Its Hormones in the Control of Reproduction in Mammals*

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12 December 2020

Circadian rhythm in experimental granulomatous inflammation is modulated by melatonin.

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12 December 2020

Identifiers

DOI

10.1385/ENDO:27:2:101

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PubMed ID

16217123

Dimensions Publication ID

13 August 2017

0 references

1 reference

PubMed ID

16217123