Further evidence that ribavirin interacts with eIF4E (Q36298008)

13 August 2017

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title

Further evidence that ribavirin interacts with eIF4E (English)

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13 August 2017

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Alex Kentsis

1

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13 August 2017

Laurent Volpon

2

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13 August 2017

Ivan Topisirovic

3

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13 August 2017

Clifford E Soll

4

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13 August 2017

Biljana Culjkovic

5

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13 August 2017

Ling Shao

6

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13 August 2017

Katherine L B Borden

7

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13 August 2017

language of work or name

English

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publication date

26 October 2005

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13 August 2017

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13 August 2017

11

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13 August 2017

12

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13 August 2017

1762-1766

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The antiviral drug ribavirin does not mimic the 7-methylguanosine moiety of the mRNA cap structure in vitro

13 August 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Ribavirin suppresses eIF4E-mediated oncogenic transformation by physical mimicry of the 7-methyl guanosine mRNA cap

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

eIF-4E expression and its role in malignancies and metastases.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Pleiotropic mechanisms of ribavirin antiviral activities

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Control of biochemical reactions through supramolecular RING domain self-assembly

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Biophysical studies of eIF4E cap-binding protein: recognition of mRNA 5' cap structure and synthetic fragments of eIF4G and 4E-BP1 proteins

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Poly(A)-binding protein interaction with elF4G stimulates picornavirus IRES-dependent translation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

PML RING suppresses oncogenic transformation by reducing the affinity of eIF4E for mRNA.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Cap-Poly(A) synergy in mammalian cell-free extracts. Investigation of the requirements for poly(A)-mediated stimulation of translation initiation

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Structure of translation factor eIF4E bound to m7GDP and interaction with 4E-binding protein

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Ribavirin is not a functional mimic of the 7-methyl guanosine mRNA cap.

30 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Tethered-function analysis reveals that elF4E can recruit ribosomes independent of its binding to the cap structure.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

Picornavirus IRESes and the poly(A) tail jointly promote cap-independent translation in a mammalian cell-free system

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

The interaction of eIF4E with 4E-BP1 is an induced fit to a completely disordered protein

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

The RING domains of the promyelocytic leukemia protein PML and the arenaviral protein Z repress translation by directly inhibiting translation initiation factor eIF4E.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

A solubility-enhancement tag (SET) for NMR studies of poorly behaving proteins.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1370864

An efficient system for cap- and poly(A)-dependent translation in vitro

22 September 2018

1 reference

12 December 2020

A spectroscopic study of the binding of m7GTP and m7GpppG to human protein synthesis initiation factor 4E

1 reference

12 December 2020

A reevaluation of the cap-binding protein, eIF4E, as a rate-limiting factor for initiation of translation in reticulocyte lysate

1 reference

12 December 2020

Internal and overall motions of the translation factor eIF4E: cap binding and insertion in a CHAPS detergent micelle

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12 December 2020

Identifiers

DOI

10.1261/RNA.2238705

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13 August 2017

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13 August 2017

PubMed publication ID

16251386

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